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N4-(3-Bromophenyl)-7-(substituted benzyl) pyrrolo[2,3-d]pyrimidines as potent multiple receptor tyrosine kinase inhibitors: design, synthesis, and in vivo evaluation.
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N4-(3-Bromophenyl)-7-(substituted benzyl) pyrrolo[2,3-d]pyrimidines as potent multiple receptor tyrosine kinase inhibitors: design, synthesis, and in vivo evaluation.
N4-(3-Bromophenyl)-7-(substituted benzyl) pyrrolo[2,3-d]pyrimidines as potent multiple receptor tyrosine kinase inhibitors: design, synthesis, and in vivo evaluation. Bioorg Med Chem. 2012 Apr 01; 20(7):2444-54.
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subject areas
Animals
Animals
Binding Sites
Binding Sites
Cell Line, Tumor
Cell Line, Tumor
Cell Movement
Cell Movement
Cell Proliferation
Cell Proliferation
Disease Models, Animal
Disease Models, Animal
Drug Design
Drug Design
Humans
Humans
Indoles
Indoles
Mice
Mice
Mice, Nude
Mice, Nude
Molecular Dynamics Simulation
Molecular Dynamics Simulation
Neoplasms
Neoplasms
Propionates
Propionates
Protein Kinase Inhibitors
Protein Kinase Inhibitors
Protein Structure, Tertiary
Protein Structure, Tertiary
Pyrimidines
Pyrimidines
Pyrroles
Pyrroles
Receptor, Platelet-Derived Growth Factor beta
Receptor, Platelet-Derived Growth Factor beta
Transplantation, Heterologous
Transplantation, Heterologous
Vascular Endothelial Growth Factor Receptor-2
Vascular Endothelial Growth Factor Receptor-2
authors with profiles
Michael Ihnat