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Human monoclonal antibodies generated following vaccination with AVA provide neutralization by blocking furin cleavage but not by preventing oligomerization.
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Human monoclonal antibodies generated following vaccination with AVA provide neutralization by blocking furin cleavage but not by preventing oligomerization.
Human monoclonal antibodies generated following vaccination with AVA provide neutralization by blocking furin cleavage but not by preventing oligomerization. Vaccine. 2012 Jun 13; 30(28):4276-83.
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PubMed
subject areas
Animals
Animals
Anthrax
Anthrax
Anthrax Vaccines
Anthrax Vaccines
Antibodies, Bacterial
Antibodies, Bacterial
Antibodies, Monoclonal
Antibodies, Monoclonal
Antibodies, Neutralizing
Antibodies, Neutralizing
Antigens, Bacterial
Antigens, Bacterial
Antitoxins
Antitoxins
Bacterial Toxins
Bacterial Toxins
Female
Female
Furin
Furin
Humans
Humans
Immunization, Passive
Immunization, Passive
Inhibitory Concentration 50
Inhibitory Concentration 50
Male
Male
Mice
Mice
Mice, Inbred A
Mice, Inbred A
Middle Aged
Middle Aged
Neutralization Tests
Neutralization Tests
Protein Multimerization
Protein Multimerization
Proteolysis
Proteolysis
authors with profiles
A. Darise Farris
Judith A James