Leucinostatins from Ophiocordyceps spp. and Purpureocillium spp. Demonstrate Selective Antiproliferative Effects in Cells Representing the Luminal Androgen Receptor Subtype of Triple Negative Breast Cancer.
Leucinostatins from Ophiocordyceps spp. and Purpureocillium spp. Demonstrate Selective Antiproliferative Effects in Cells Representing the Luminal Androgen Receptor Subtype of Triple Negative Breast Cancer. J Nat Prod. 2020 06 26; 83(6):2010-2024.
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Antibiotics, Antineoplastic
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Antibiotics, Antineoplastic
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Antimicrobial Cationic Peptides
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Antimicrobial Cationic Peptides
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Ascomycota
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Ascomycota
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Cell Line, Tumor
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Cell Line, Tumor
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Chromatography, High Pressure Liquid
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Chromatography, High Pressure Liquid
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Cordyceps
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Cordyceps
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Drug Screening Assays, Antitumor
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Drug Screening Assays, Antitumor
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Female
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Female
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Humans
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Humans
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Hydrolysis
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Hydrolysis
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Magnetic Resonance Spectroscopy
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Magnetic Resonance Spectroscopy
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Mitochondria
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Mitochondria
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Oxygen Consumption
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Oxygen Consumption
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Receptors, Androgen
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Receptors, Androgen
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Spectrometry, Mass, Electrospray Ionization
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Spectrometry, Mass, Electrospray Ionization
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Triple Negative Breast Neoplasms
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Triple Negative Breast Neoplasms