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Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients.
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Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients.
Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients. Genes Immun. 2008 Jun; 9(4):368-78.
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subject areas
Animals
Animals
CD11a Antigen
CD11a Antigen
CD27 Ligand
CD27 Ligand
Cell Separation
Cell Separation
Cells, Cultured
Cells, Cultured
Disease Models, Animal
Disease Models, Animal
Doxycycline
Doxycycline
Extracellular Signal-Regulated MAP Kinases
Extracellular Signal-Regulated MAP Kinases
Gene Expression Regulation
Gene Expression Regulation
Humans
Humans
Interferons
Interferons
Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
Methylation
Methylation
Methyltransferases
Methyltransferases
Mice
Mice
Mice, Inbred C57BL
Mice, Inbred C57BL
Mice, Transgenic
Mice, Transgenic
Models, Genetic
Models, Genetic
Oligonucleotide Array Sequence Analysis
Oligonucleotide Array Sequence Analysis
Repressor Proteins
Repressor Proteins
RNA, Messenger
RNA, Messenger
T-Lymphocytes
T-Lymphocytes
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Matlock Arizona Jeffries