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Autophagy augmentation alleviates cigarette smoke-induced CFTR-dysfunction, ceramide-accumulation and COPD-emphysema pathogenesis.
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Autophagy augmentation alleviates cigarette smoke-induced CFTR-dysfunction, ceramide-accumulation and COPD-emphysema pathogenesis.
Autophagy augmentation alleviates cigarette smoke-induced CFTR-dysfunction, ceramide-accumulation and COPD-emphysema pathogenesis. Free Radic Biol Med. 2019 02 01; 131:81-97.
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subject areas
Acid Ceramidase
Acid Ceramidase
Animals
Animals
Antioxidants
Antioxidants
Autophagy
Autophagy
Bronchi
Bronchi
Case-Control Studies
Case-Control Studies
Cell Line
Cell Line
Ceramides
Ceramides
Complex Mixtures
Complex Mixtures
Cysteamine
Cysteamine
Cystic Fibrosis Transmembrane Conductance Regulator
Cystic Fibrosis Transmembrane Conductance Regulator
Emphysema
Emphysema
Epithelial Cells
Epithelial Cells
Gemfibrozil
Gemfibrozil
Gene Expression
Gene Expression
Humans
Humans
Hypolipidemic Agents
Hypolipidemic Agents
Male
Male
Mice
Mice
Mice, Inbred C57BL
Mice, Inbred C57BL
Pulmonary Disease, Chronic Obstructive
Pulmonary Disease, Chronic Obstructive
Smoking
Smoking
Tobacco
Tobacco