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The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells.
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The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells.
The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells. Mol Cancer Ther. 2002 Nov; 1(13):1201-9.
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PubMed
subject areas
Administration, Oral
Administration, Oral
Animals
Animals
Antinematodal Agents
Antinematodal Agents
Antineoplastic Agents, Phytogenic
Antineoplastic Agents, Phytogenic
Apoptosis
Apoptosis
Biomarkers, Tumor
Biomarkers, Tumor
Blotting, Western
Blotting, Western
Carcinoma, Non-Small-Cell Lung
Carcinoma, Non-Small-Cell Lung
Caspases
Caspases
Cell Cycle
Cell Cycle
Cytochrome c Group
Cytochrome c Group
Flow Cytometry
Flow Cytometry
Humans
Humans
In Situ Nick-End Labeling
In Situ Nick-End Labeling
Lung Neoplasms
Lung Neoplasms
Mebendazole
Mebendazole
Mice
Mice
Mice, Nude
Mice, Nude
Microscopy, Fluorescence
Microscopy, Fluorescence
Mitochondria
Mitochondria
Paclitaxel
Paclitaxel
Spindle Apparatus
Spindle Apparatus
Tubulin
Tubulin
Tumor Cells, Cultured
Tumor Cells, Cultured
authors with profiles
Rajagopal Ramesh