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Bile acids regulate cysteine catabolism and glutathione regeneration to modulate hepatic sensitivity to oxidative injury.
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Bile acids regulate cysteine catabolism and glutathione regeneration to modulate hepatic sensitivity to oxidative injury.
Bile acids regulate cysteine catabolism and glutathione regeneration to modulate hepatic sensitivity to oxidative injury. JCI Insight. 2018 04 19; 3(8).
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subject areas
Acetaminophen
Acetaminophen
Acetylcysteine
Acetylcysteine
Analgesics, Non-Narcotic
Analgesics, Non-Narcotic
Animals
Animals
Anticholesteremic Agents
Anticholesteremic Agents
Bile Acids and Salts
Bile Acids and Salts
Cholestyramine Resin
Cholestyramine Resin
Cysteine
Cysteine
Free Radical Scavengers
Free Radical Scavengers
Glutathione
Glutathione
Hepatocytes
Hepatocytes
Homeostasis
Homeostasis
Liver
Liver
Male
Male
Mice
Mice
Mice, Inbred C57BL
Mice, Inbred C57BL
Oxidative Stress
Oxidative Stress