Header Logo

Connection

Jimmy Ballard to Animals

This is a "connection" page, showing publications Jimmy Ballard has written about Animals.
Connection Strength

1.511
  1. A sequence invariable region in TcdB2 is required for toxin escape from Clostridioides difficile. J Bacteriol. 2024 07 25; 206(7):e0009624.
    View in: PubMed
    Score: 0.089
  2. Discovery of Hippo signaling as a regulator of CSPG4 expression and as a therapeutic target for Clostridioides difficile disease. PLoS Pathog. 2023 03; 19(3):e1011272.
    View in: PubMed
    Score: 0.081
  3. Deletion of a 19-Amino-Acid Region in Clostridioides difficile TcdB2 Results in Spontaneous Autoprocessing and Reduced Cell Binding and Provides a Nontoxic Immunogen for Vaccination. Infect Immun. 2019 08; 87(8).
    View in: PubMed
    Score: 0.063
  4. Unique, Intersecting, and Overlapping Roles of C/EBP ß and CREB in Cells of the Innate Immune System. Sci Rep. 2018 11 16; 8(1):16931.
    View in: PubMed
    Score: 0.060
  5. Cell-penetrating peptides derived from Clostridium difficile TcdB2 and a related large clostridial toxin. J Biol Chem. 2018 02 02; 293(5):1810-1819.
    View in: PubMed
    Score: 0.056
  6. Intrinsic Toxin-Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB. mBio. 2017 05 16; 8(3).
    View in: PubMed
    Score: 0.054
  7. Exposure of neutralizing epitopes in the carboxyl-terminal domain of TcdB is altered by a proximal hypervariable region. J Biol Chem. 2015 Mar 13; 290(11):6975-85.
    View in: PubMed
    Score: 0.046
  8. Variations in virulence and molecular biology among emerging strains of Clostridium difficile. Microbiol Mol Biol Rev. 2013 Dec; 77(4):567-81.
    View in: PubMed
    Score: 0.043
  9. Clostridium difficile 027/BI/NAP1 encodes a hypertoxic and antigenically variable form of TcdB. PLoS Pathog. 2013; 9(8):e1003523.
    View in: PubMed
    Score: 0.042
  10. Increased cAMP in monocytes augments Notch signaling mechanisms by elevating RBP-J and transducin-like enhancer of Split (TLE). J Biol Chem. 2013 Jul 26; 288(30):21526-36.
    View in: PubMed
    Score: 0.041
  11. Differential inflammatory responses triggered by toxic small molecules. Environ Sci Pollut Res Int. 2012 Mar; 19(3):619-27.
    View in: PubMed
    Score: 0.037
  12. Glycogen synthase kinase 3 activation is important for anthrax edema toxin-induced dendritic cell maturation and anthrax toxin receptor 2 expression in macrophages. Infect Immun. 2011 Aug; 79(8):3302-8.
    View in: PubMed
    Score: 0.036
  13. Adenomatous polyposis coli protein associates with C/EBP beta and increases Bacillus anthracis edema toxin-stimulated gene expression in macrophages. J Biol Chem. 2011 Jun 03; 286(22):19364-72.
    View in: PubMed
    Score: 0.036
  14. Medical microbiology: A toxin contest. Nature. 2010 Oct 07; 467(7316):665-6.
    View in: PubMed
    Score: 0.034
  15. Variations in TcdB activity and the hypervirulence of emerging strains of Clostridium difficile. PLoS Pathog. 2010 Aug 19; 6(8):e1001061.
    View in: PubMed
    Score: 0.034
  16. Regulatory interactions of a virulence-associated serine/threonine phosphatase-kinase pair in Bacillus anthracis. J Bacteriol. 2010 Jan; 192(2):400-9.
    View in: PubMed
    Score: 0.032
  17. The mechanism of Bacillus anthracis intracellular germination requires multiple and highly diverse genetic loci. Infect Immun. 2009 Jan; 77(1):23-31.
    View in: PubMed
    Score: 0.030
  18. Bacillus anthracis edema toxin activates nuclear glycogen synthase kinase 3beta. Infect Immun. 2008 Nov; 76(11):4895-904.
    View in: PubMed
    Score: 0.030
  19. Effects of endogenous D-alanine synthesis and autoinhibition of Bacillus anthracis germination on in vitro and in vivo infections. Infect Immun. 2007 Dec; 75(12):5726-34.
    View in: PubMed
    Score: 0.028
  20. Critical intermediate steps in Clostridium sordellii lethal toxin-induced apoptosis. Biochem Biophys Res Commun. 2007 Nov 30; 363(4):959-64.
    View in: PubMed
    Score: 0.028
  21. Elucidating the in vivo targets of bacterial toxins. Future Microbiol. 2007 Feb; 2(1):85-92.
    View in: PubMed
    Score: 0.027
  22. Identification of Clostridium difficile toxin B cardiotoxicity using a zebrafish embryo model of intoxication. Proc Natl Acad Sci U S A. 2006 Sep 19; 103(38):14176-81.
    View in: PubMed
    Score: 0.026
  23. Cytotoxic activity of Bacillus anthracis protective antigen observed in a macrophage cell line overexpressing ANTXR1. Cell Microbiol. 2006 Aug; 8(8):1272-81.
    View in: PubMed
    Score: 0.026
  24. Variations in lethal toxin and cholesterol-dependent cytolysin production correspond to differences in cytotoxicity among strains of Clostridium sordellii. FEMS Microbiol Lett. 2006 Jun; 259(2):295-302.
    View in: PubMed
    Score: 0.025
  25. Bacillus anthracis oedema toxin as a cause of tissue necrosis and cell type-specific cytotoxicity. Cell Microbiol. 2005 Aug; 7(8):1139-49.
    View in: PubMed
    Score: 0.024
  26. Clostridium difficile toxins: mechanism of action and role in disease. Clin Microbiol Rev. 2005 Apr; 18(2):247-63.
    View in: PubMed
    Score: 0.023
  27. Clostridioides difficile toxin B subverts germinal center and antibody recall responses by stimulating a drug-treatable CXCR4-dependent mechanism. Cell Rep. 2024 May 28; 43(5):114245.
    View in: PubMed
    Score: 0.022
  28. Toxin-induced resistance in Bacillus anthracis lethal toxin-treated macrophages. Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21):12426-31.
    View in: PubMed
    Score: 0.021
  29. Decreased glycogen synthase kinase 3-beta levels and related physiological changes in Bacillus anthracis lethal toxin-treated macrophages. Cell Microbiol. 2003 Aug; 5(8):523-32.
    View in: PubMed
    Score: 0.021
  30. Mutational analysis of the enzymatic domain of Clostridium difficile toxin B reveals novel inhibitors of the wild-type toxin. Infect Immun. 2003 Jun; 71(6):3294-301.
    View in: PubMed
    Score: 0.021
  31. Clostridium difficile toxin B activates dual caspase-dependent and caspase-independent apoptosis in intoxicated cells. Cell Microbiol. 2002 Jul; 4(7):425-34.
    View in: PubMed
    Score: 0.019
  32. Use of a Clostridioides difficile Murine Immunization and Challenge Model to Evaluate Single and Combination Vaccine Adjuvants Consisting of Alum and NKT Cell-Activating Ligands. Front Immunol. 2021; 12:818734.
    View in: PubMed
    Score: 0.019
  33. pH-enhanced cytopathic effects of Clostridium sordellii lethal toxin. Infect Immun. 2001 Sep; 69(9):5487-93.
    View in: PubMed
    Score: 0.018
  34. a-Galactosylceramide-Reactive NKT Cells Increase IgG1 Class Switch against a Clostridioides difficile Polysaccharide Antigen and Enhance Immunity against a Live Pathogen Challenge. Infect Immun. 2021 10 15; 89(11):e0043821.
    View in: PubMed
    Score: 0.018
  35. The Murine Neonatal Fc Receptor Is Required for Transport of Immunization-Induced C. difficile-Specific IgG to the Gut and Protection against Disease but Does Not Affect Disease Susceptibility. Infect Immun. 2021 09 16; 89(10):e0027421.
    View in: PubMed
    Score: 0.018
  36. Cytosolic delivery and characterization of the TcdB glucosylating domain by using a heterologous protein fusion. Infect Immun. 2001 Jan; 69(1):599-601.
    View in: PubMed
    Score: 0.017
  37. Human C. difficile toxin-specific memory B cell repertoires encode poorly neutralizing antibodies. JCI Insight. 2020 08 20; 5(16).
    View in: PubMed
    Score: 0.017
  38. pH-induced conformational changes in Clostridium difficile toxin B. Infect Immun. 2000 May; 68(5):2470-4.
    View in: PubMed
    Score: 0.017
  39. Clostridioides difficile Infection Induces an Inferior IgG Response to That Induced by Immunization and Is Associated with a Lack of T Follicular Helper Cell and Memory B Cell Expansion. Infect Immun. 2020 02 20; 88(3).
    View in: PubMed
    Score: 0.016
  40. Anthrax toxin as a molecular tool for stimulation of cytotoxic T lymphocytes: disulfide-linked epitopes, multiple injections, and role of CD4(+) cells. Infect Immun. 1998 Oct; 66(10):4696-9.
    View in: PubMed
    Score: 0.015
  41. Anthrax toxin-mediated delivery in vivo and in vitro of a cytotoxic T-lymphocyte epitope from ovalbumin. Infect Immun. 1998 Feb; 66(2):615-9.
    View in: PubMed
    Score: 0.014
  42. Anthrax Vaccine Precipitated Induces Edema Toxin-Neutralizing, Edema Factor-Specific Antibodies in Human Recipients. Clin Vaccine Immunol. 2017 Nov; 24(11).
    View in: PubMed
    Score: 0.014
  43. Anthrax toxin-mediated delivery of a cytotoxic T-cell epitope in vivo. Proc Natl Acad Sci U S A. 1996 Oct 29; 93(22):12531-4.
    View in: PubMed
    Score: 0.013
  44. Coordination between T helper cells, iNKT cells, and their follicular helper subsets in the humoral immune response against Clostridium difficile toxin B. J Leukoc Biol. 2017 02; 101(2):567-576.
    View in: PubMed
    Score: 0.013
  45. Memory B Cells Encode Neutralizing Antibody Specific for Toxin B from the Clostridium difficile Strains VPI 10463 and NAP1/BI/027 but with Superior Neutralization of VPI 10463 Toxin B. Infect Immun. 2016 01; 84(1):194-204.
    View in: PubMed
    Score: 0.012
  46. Immunization of Mice with Anthrax Protective Antigen Limits Cardiotoxicity but Not Hepatotoxicity Following Lethal Toxin Challenge. Toxins (Basel). 2015 Jun 25; 7(7):2371-84.
    View in: PubMed
    Score: 0.012
  47. Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function. Infect Immun. 2012 Dec; 80(12):4374-87.
    View in: PubMed
    Score: 0.010
  48. Purification and characterization of the lethal toxin (alpha-toxin) of Clostridium septicum. Infect Immun. 1992 Mar; 60(3):784-90.
    View in: PubMed
    Score: 0.009
  49. Serum amyloid A protects murine macrophages from lethal toxin-mediated death. Cell Immunol. 2012; 272(2):175-81.
    View in: PubMed
    Score: 0.009
  50. Regulation of anthrax toxin-specific antibody titers by natural killer T cell-derived IL-4 and IFN?. PLoS One. 2011; 6(8):e23817.
    View in: PubMed
    Score: 0.009
  51. Anthrax vaccination induced anti-lethal factor IgG: fine specificity and neutralizing capacity. Vaccine. 2011 May 09; 29(20):3670-8.
    View in: PubMed
    Score: 0.009
  52. Select human anthrax protective antigen epitope-specific antibodies provide protection from lethal toxin challenge. J Infect Dis. 2010 Jul 15; 202(2):251-60.
    View in: PubMed
    Score: 0.008
  53. Inflammatory cytokine response to Bacillus anthracis peptidoglycan requires phagocytosis and lysosomal trafficking. Infect Immun. 2010 Jun; 78(6):2418-28.
    View in: PubMed
    Score: 0.008
  54. CD1d-dependent B-cell help by NK-like T cells leads to enhanced and sustained production of Bacillus anthracis lethal toxin-neutralizing antibodies. Infect Immun. 2010 Apr; 78(4):1610-7.
    View in: PubMed
    Score: 0.008
  55. Resistance of human alveolar macrophages to Bacillus anthracis lethal toxin. J Immunol. 2009 Nov 01; 183(9):5799-806.
    View in: PubMed
    Score: 0.008
  56. Bacillus anthracis lethal toxin disrupts TCR signaling in CD1d-restricted NKT cells leading to functional anergy. PLoS Pathog. 2009 Sep; 5(9):e1000588.
    View in: PubMed
    Score: 0.008
  57. The major neutralizing antibody responses to recombinant anthrax lethal and edema factors are directed to non-cross-reactive epitopes. Infect Immun. 2009 Nov; 77(11):4714-23.
    View in: PubMed
    Score: 0.008
  58. Sequential B-cell epitopes of Bacillus anthracis lethal factor bind lethal toxin-neutralizing antibodies. Infect Immun. 2009 Jan; 77(1):162-9.
    View in: PubMed
    Score: 0.008
  59. High-throughput, single-cell analysis of macrophage interactions with fluorescently labeled Bacillus anthracis spores. Appl Environ Microbiol. 2008 Aug; 74(16):5201-10.
    View in: PubMed
    Score: 0.007
  60. Mapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):13803-8.
    View in: PubMed
    Score: 0.005
  61. Cytotoxic T-lymphocyte epitopes fused to anthrax toxin induce protective antiviral immunity. Infect Immun. 1999 Jul; 67(7):3290-6.
    View in: PubMed
    Score: 0.004
  62. Ltx1, a mouse locus that influences the susceptibility of macrophages to cytolysis caused by intoxication with Bacillus anthracis lethal factor, maps to chromosome 11. Mol Microbiol. 1998 Jul; 29(2):581-91.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.