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Jimmy Ballard to Bacterial Toxins

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This is a "connection" page, showing publications Jimmy Ballard has written about Bacterial Toxins.
Jimmy Ballard
Connection Strength
10.747
Bacterial Toxins
  1. A sequence invariable region in TcdB2 is required for toxin escape from Clostridioides difficile. J Bacteriol. 2024 07 25; 206(7):e0009624.
    View in: PubMed
    Score: 0.721
  2. Discovery of Hippo signaling as a regulator of CSPG4 expression and as a therapeutic target for Clostridioides difficile disease. PLoS Pathog. 2023 03; 19(3):e1011272.
    View in: PubMed
    Score: 0.662
  3. Combined and Distinct Roles of Agr Proteins in Clostridioides difficile 630 Sporulation, Motility, and Toxin Production. mBio. 2020 12 22; 11(6).
    View in: PubMed
    Score: 0.566
  4. Cell-penetrating peptides derived from Clostridium difficile TcdB2 and a related large clostridial toxin. J Biol Chem. 2018 02 02; 293(5):1810-1819.
    View in: PubMed
    Score: 0.459
  5. Intrinsic Toxin-Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB. mBio. 2017 05 16; 8(3).
    View in: PubMed
    Score: 0.441
  6. Exposure of neutralizing epitopes in the carboxyl-terminal domain of TcdB is altered by a proximal hypervariable region. J Biol Chem. 2015 Mar 13; 290(11):6975-85.
    View in: PubMed
    Score: 0.375
  7. Clostridium difficile 027/BI/NAP1 encodes a hypertoxic and antigenically variable form of TcdB. PLoS Pathog. 2013; 9(8):e1003523.
    View in: PubMed
    Score: 0.339
  8. Toxin inhibition of antimicrobial factors induced by Bacillus anthracis peptidoglycan in human blood. Infect Immun. 2013 Oct; 81(10):3693-702.
    View in: PubMed
    Score: 0.338
  9. TcdB from hypervirulent Clostridium difficile exhibits increased efficiency of autoprocessing. Mol Microbiol. 2012 Apr; 84(1):66-76.
    View in: PubMed
    Score: 0.307
  10. Glycogen synthase kinase 3 activation is important for anthrax edema toxin-induced dendritic cell maturation and anthrax toxin receptor 2 expression in macrophages. Infect Immun. 2011 Aug; 79(8):3302-8.
    View in: PubMed
    Score: 0.291
  11. Adenomatous polyposis coli protein associates with C/EBP beta and increases Bacillus anthracis edema toxin-stimulated gene expression in macrophages. J Biol Chem. 2011 Jun 03; 286(22):19364-72.
    View in: PubMed
    Score: 0.289
  12. Medical microbiology: A toxin contest. Nature. 2010 Oct 07; 467(7316):665-6.
    View in: PubMed
    Score: 0.279
  13. Variations in TcdB activity and the hypervirulence of emerging strains of Clostridium difficile. PLoS Pathog. 2010 Aug 19; 6(8):e1001061.
    View in: PubMed
    Score: 0.276
  14. Bacillus anthracis edema toxin activates nuclear glycogen synthase kinase 3beta. Infect Immun. 2008 Nov; 76(11):4895-904.
    View in: PubMed
    Score: 0.241
  15. Critical intermediate steps in Clostridium sordellii lethal toxin-induced apoptosis. Biochem Biophys Res Commun. 2007 Nov 30; 363(4):959-64.
    View in: PubMed
    Score: 0.226
  16. Elucidating the in vivo targets of bacterial toxins. Future Microbiol. 2007 Feb; 2(1):85-92.
    View in: PubMed
    Score: 0.216
  17. Identification of Clostridium difficile toxin B cardiotoxicity using a zebrafish embryo model of intoxication. Proc Natl Acad Sci U S A. 2006 Sep 19; 103(38):14176-81.
    View in: PubMed
    Score: 0.210
  18. Cytotoxic activity of Bacillus anthracis protective antigen observed in a macrophage cell line overexpressing ANTXR1. Cell Microbiol. 2006 Aug; 8(8):1272-81.
    View in: PubMed
    Score: 0.209
  19. Variations in lethal toxin and cholesterol-dependent cytolysin production correspond to differences in cytotoxicity among strains of Clostridium sordellii. FEMS Microbiol Lett. 2006 Jun; 259(2):295-302.
    View in: PubMed
    Score: 0.206
  20. Clostridium difficile toxins: mechanism of action and role in disease. Clin Microbiol Rev. 2005 Apr; 18(2):247-63.
    View in: PubMed
    Score: 0.190
  21. Clostridium sordellii lethal toxin is maintained in a multimeric protein complex. Infect Immun. 2004 Jun; 72(6):3366-72.
    View in: PubMed
    Score: 0.180
  22. Clostridioides difficile toxin B subverts germinal center and antibody recall responses by stimulating a drug-treatable CXCR4-dependent mechanism. Cell Rep. 2024 May 28; 43(5):114245.
    View in: PubMed
    Score: 0.179
  23. Toxin-induced resistance in Bacillus anthracis lethal toxin-treated macrophages. Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21):12426-31.
    View in: PubMed
    Score: 0.171
  24. Decreased glycogen synthase kinase 3-beta levels and related physiological changes in Bacillus anthracis lethal toxin-treated macrophages. Cell Microbiol. 2003 Aug; 5(8):523-32.
    View in: PubMed
    Score: 0.169
  25. Mutational analysis of the enzymatic domain of Clostridium difficile toxin B reveals novel inhibitors of the wild-type toxin. Infect Immun. 2003 Jun; 71(6):3294-301.
    View in: PubMed
    Score: 0.168
  26. Clostridium difficile toxin B activates dual caspase-dependent and caspase-independent apoptosis in intoxicated cells. Cell Microbiol. 2002 Jul; 4(7):425-34.
    View in: PubMed
    Score: 0.157
  27. Clostridioides difficile Toxin B Activates Group 3 Innate Lymphocytes. Infect Immun. 2022 04 21; 90(4):e0007322.
    View in: PubMed
    Score: 0.155
  28. pH-enhanced cytopathic effects of Clostridium sordellii lethal toxin. Infect Immun. 2001 Sep; 69(9):5487-93.
    View in: PubMed
    Score: 0.148
  29. Cytosolic delivery and characterization of the TcdB glucosylating domain by using a heterologous protein fusion. Infect Immun. 2001 Jan; 69(1):599-601.
    View in: PubMed
    Score: 0.142
  30. Human C. difficile toxin-specific memory B cell repertoires encode poorly neutralizing antibodies. JCI Insight. 2020 08 20; 5(16).
    View in: PubMed
    Score: 0.138
  31. pH-induced conformational changes in Clostridium difficile toxin B. Infect Immun. 2000 May; 68(5):2470-4.
    View in: PubMed
    Score: 0.135
  32. Toxin-neutralizing antibodies elicited by naturally acquired cutaneous anthrax are elevated following severe disease and appear to target conformational epitopes. PLoS One. 2020; 15(4):e0230782.
    View in: PubMed
    Score: 0.135
  33. Anthrax toxin as a molecular tool for stimulation of cytotoxic T lymphocytes: disulfide-linked epitopes, multiple injections, and role of CD4(+) cells. Infect Immun. 1998 Oct; 66(10):4696-9.
    View in: PubMed
    Score: 0.121
  34. Anthrax toxin-mediated delivery in vivo and in vitro of a cytotoxic T-lymphocyte epitope from ovalbumin. Infect Immun. 1998 Feb; 66(2):615-9.
    View in: PubMed
    Score: 0.116
  35. Anthrax Vaccine Precipitated Induces Edema Toxin-Neutralizing, Edema Factor-Specific Antibodies in Human Recipients. Clin Vaccine Immunol. 2017 Nov; 24(11).
    View in: PubMed
    Score: 0.114
  36. Anthrax toxin-mediated delivery of a cytotoxic T-cell epitope in vivo. Proc Natl Acad Sci U S A. 1996 Oct 29; 93(22):12531-4.
    View in: PubMed
    Score: 0.106
  37. Coordination between T helper cells, iNKT cells, and their follicular helper subsets in the humoral immune response against Clostridium difficile toxin B. J Leukoc Biol. 2017 02; 101(2):567-576.
    View in: PubMed
    Score: 0.105
  38. Memory B Cells Encode Neutralizing Antibody Specific for Toxin B from the Clostridium difficile Strains VPI 10463 and NAP1/BI/027 but with Superior Neutralization of VPI 10463 Toxin B. Infect Immun. 2016 01; 84(1):194-204.
    View in: PubMed
    Score: 0.099
  39. Immunization of Mice with Anthrax Protective Antigen Limits Cardiotoxicity but Not Hepatotoxicity Following Lethal Toxin Challenge. Toxins (Basel). 2015 Jun 25; 7(7):2371-84.
    View in: PubMed
    Score: 0.097
  40. The primary structure of Clostridium septicum alpha-toxin exhibits similarity with that of Aeromonas hydrophila aerolysin. Infect Immun. 1995 Jan; 63(1):340-4.
    View in: PubMed
    Score: 0.094
  41. Activation and mechanism of Clostridium septicum alpha toxin. Mol Microbiol. 1993 Nov; 10(3):627-34.
    View in: PubMed
    Score: 0.086
  42. Increased cAMP in monocytes augments Notch signaling mechanisms by elevating RBP-J and transducin-like enhancer of Split (TLE). J Biol Chem. 2013 Jul 26; 288(30):21526-36.
    View in: PubMed
    Score: 0.084
  43. Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function. Infect Immun. 2012 Dec; 80(12):4374-87.
    View in: PubMed
    Score: 0.080
  44. Purification and characterization of the lethal toxin (alpha-toxin) of Clostridium septicum. Infect Immun. 1992 Mar; 60(3):784-90.
    View in: PubMed
    Score: 0.077
  45. Serum amyloid A protects murine macrophages from lethal toxin-mediated death. Cell Immunol. 2012; 272(2):175-81.
    View in: PubMed
    Score: 0.075
  46. Regulation of anthrax toxin-specific antibody titers by natural killer T cell-derived IL-4 and IFN?. PLoS One. 2011; 6(8):e23817.
    View in: PubMed
    Score: 0.074
  47. Anthrax vaccination induced anti-lethal factor IgG: fine specificity and neutralizing capacity. Vaccine. 2011 May 09; 29(20):3670-8.
    View in: PubMed
    Score: 0.072
  48. CD1d-dependent B-cell help by NK-like T cells leads to enhanced and sustained production of Bacillus anthracis lethal toxin-neutralizing antibodies. Infect Immun. 2010 Apr; 78(4):1610-7.
    View in: PubMed
    Score: 0.067
  49. Clostridium sordellii toxic shock syndrome. Lancet Infect Dis. 2009 Dec; 9(12):725-6.
    View in: PubMed
    Score: 0.066
  50. Resistance of human alveolar macrophages to Bacillus anthracis lethal toxin. J Immunol. 2009 Nov 01; 183(9):5799-806.
    View in: PubMed
    Score: 0.065
  51. Bacillus anthracis lethal toxin disrupts TCR signaling in CD1d-restricted NKT cells leading to functional anergy. PLoS Pathog. 2009 Sep; 5(9):e1000588.
    View in: PubMed
    Score: 0.065
  52. The major neutralizing antibody responses to recombinant anthrax lethal and edema factors are directed to non-cross-reactive epitopes. Infect Immun. 2009 Nov; 77(11):4714-23.
    View in: PubMed
    Score: 0.065
  53. Sequential B-cell epitopes of Bacillus anthracis lethal factor bind lethal toxin-neutralizing antibodies. Infect Immun. 2009 Jan; 77(1):162-9.
    View in: PubMed
    Score: 0.061
  54. Bacillus anthracis oedema toxin as a cause of tissue necrosis and cell type-specific cytotoxicity. Cell Microbiol. 2005 Aug; 7(8):1139-49.
    View in: PubMed
    Score: 0.049
  55. Mapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):13803-8.
    View in: PubMed
    Score: 0.043
  56. The Murine Neonatal Fc Receptor Is Required for Transport of Immunization-Induced C. difficile-Specific IgG to the Gut and Protection against Disease but Does Not Affect Disease Susceptibility. Infect Immun. 2021 09 16; 89(10):e0027421.
    View in: PubMed
    Score: 0.037
  57. Clostridioides difficile Infection Induces an Inferior IgG Response to That Induced by Immunization and Is Associated with a Lack of T Follicular Helper Cell and Memory B Cell Expansion. Infect Immun. 2020 02 20; 88(3).
    View in: PubMed
    Score: 0.033
  58. Cytotoxic T-lymphocyte epitopes fused to anthrax toxin induce protective antiviral immunity. Infect Immun. 1999 Jul; 67(7):3290-6.
    View in: PubMed
    Score: 0.032
  59. Ltx1, a mouse locus that influences the susceptibility of macrophages to cytolysis caused by intoxication with Bacillus anthracis lethal factor, maps to chromosome 11. Mol Microbiol. 1998 Jul; 29(2):581-91.
    View in: PubMed
    Score: 0.030
  60. Select human anthrax protective antigen epitope-specific antibodies provide protection from lethal toxin challenge. J Infect Dis. 2010 Jul 15; 202(2):251-60.
    View in: PubMed
    Score: 0.017
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.