Christina Bourne to Trimethoprim
                            
                            
                                This is a "connection" page, showing publications Christina Bourne has written about Trimethoprim.
                            
                            
                            
                                
                                    
                                            
    
        
        
        
            Connection Strength
            
                
            
            0.487
         
        
        
     
 
    
        
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            Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity. Antimicrob Agents Chemother. 2009 Jul; 53(7):3065-73.
            
            
                Score: 0.316
             
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            Inhibitor design to target a unique feature in the folate pocket of Staphylococcus aureus dihydrofolate reductase. Eur J Med Chem. 2020 Aug 15; 200:112412.
            
            
                Score: 0.171