Christina Bourne to Bacillus anthracis
This is a "connection" page, showing publications Christina Bourne has written about Bacillus anthracis.
Connection Strength
1.201
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Structure-activity relationship for enantiomers of potent inhibitors of B. anthracis dihydrofolate reductase. Biochim Biophys Acta. 2013 Jan; 1834(1):46-52.
Score: 0.374
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Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity. Antimicrob Agents Chemother. 2009 Jul; 53(7):3065-73.
Score: 0.295
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Evaluation of New Dihydrophthalazine-Appended 2,4-Diaminopyrimidines against Bacillus anthracis: Improved Syntheses Using a New Pincer Complex. Molecules. 2015 Apr 21; 20(4):7222-44.
Score: 0.112
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Modified 2,4-diaminopyrimidine-based dihydrofolate reductase inhibitors as potential drug scaffolds against Bacillus anthracis. Bioorg Med Chem. 2015 Jan 01; 23(1):203-11.
Score: 0.109
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Synthesis and biological evaluation of 2,4-diaminopyrimidine-based antifolate drugs against Bacillus anthracis. Molecules. 2014 Mar 17; 19(3):3231-46.
Score: 0.104
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Inhibition of bacterial dihydrofolate reductase by 6-alkyl-2,4-diaminopyrimidines. ChemMedChem. 2012 Nov; 7(11):1974-82.
Score: 0.093
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Synthesis and biological activity of substituted 2,4-diaminopyrimidines that inhibit Bacillus anthracis. Eur J Med Chem. 2012 Aug; 54:387-96.
Score: 0.091
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High-throughput screening of a diversity collection using biodefense category A and B priority pathogens. J Biomol Screen. 2012 Aug; 17(7):946-56.
Score: 0.023