Judith James to Lupus Erythematosus, Systemic
This is a "connection" page, showing publications Judith James has written about Lupus Erythematosus, Systemic.
Connection Strength
21.759
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Neutrophils isolated from systemic lupus erythematosus patients exhibit a distinct functional phenotype. Front Immunol. 2024; 15:1339250.
Score: 0.537
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Mycophenolate mofetil withdrawal in patients with systemic lupus erythematosus: a multicentre, open-label, randomised controlled trial. Lancet Rheumatol. 2024 Mar; 6(3):e168-e177.
Score: 0.533
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Pre-Clinical Autoimmunity in Lupus Relatives: Self-Reported Questionnaires and Immune Dysregulation Distinguish Relatives Who Develop Incomplete or Classified Lupus From Clinically Unaffected Relatives and Unaffected, Unrelated Individuals. Front Immunol. 2022; 13:866181.
Score: 0.475
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Epstein-Barr Functional Mimicry: Pathogenicity of Oncogenic Latent Membrane Protein-1 in Systemic Lupus Erythematosus and Autoimmunity. Front Immunol. 2020; 11:606936.
Score: 0.433
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Epstein Barr Virus and Autoimmune Responses in Systemic Lupus Erythematosus. Front Immunol. 2020; 11:623944.
Score: 0.433
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Autoantibody-positive healthy individuals with lower lupus risk display a unique immune endotype. J Allergy Clin Immunol. 2020 12; 146(6):1419-1433.
Score: 0.413
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Association of Epstein-Barr virus serological reactivation with transitioning to systemic lupus erythematosus in at-risk individuals. Ann Rheum Dis. 2019 09; 78(9):1235-1241.
Score: 0.387
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Immunologic findings precede rapid lupus flare after transient steroid therapy. Sci Rep. 2019 06 13; 9(1):8590.
Score: 0.387
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Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients. EBioMedicine. 2019 Apr; 42:76-85.
Score: 0.381
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Biomarkers in connective tissue diseases. J Allergy Clin Immunol. 2017 Dec; 140(6):1473-1483.
Score: 0.348
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Clinical and Serologic Features in Patients With Incomplete Lupus Classification Versus Systemic Lupus Erythematosus Patients and Controls. Arthritis Care Res (Hoboken). 2017 12; 69(12):1780-1788.
Score: 0.347
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Discerning Risk of Disease Transition in Relatives of Systemic Lupus Erythematosus Patients Utilizing Soluble Mediators and Clinical Features. Arthritis Rheumatol. 2017 03; 69(3):630-642.
Score: 0.330
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Pathways of impending disease flare in African-American systemic lupus erythematosus patients. J Autoimmun. 2017 03; 78:70-78.
Score: 0.328
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Autoantibody-Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity. Arthritis Rheumatol. 2016 10; 68(10):2492-502.
Score: 0.321
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Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies. J Autoimmun. 2016 11; 74:182-193.
Score: 0.314
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Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification. Ann Rheum Dis. 2016 Nov; 75(11):2014-2021.
Score: 0.306
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Barriers And Motivators for Smoking Cessation in Patients With Systemic Lupus Erythematosus (SLE). J Okla State Med Assoc. 2015 Nov; 108(11):492-9.
Score: 0.301
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Preclinical lupus. Curr Opin Rheumatol. 2015 Sep; 27(5):433-9.
Score: 0.297
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Influenza A (H1N1) virus infection triggers severe pulmonary inflammation in lupus-prone mice following viral clearance. J Autoimmun. 2015 Feb; 57:66-76.
Score: 0.284
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Preclinical systemic lupus erythematosus. Rheum Dis Clin North Am. 2014 Nov; 40(4):621-35.
Score: 0.278
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Proinflammatory adaptive cytokine and shed tumor necrosis factor receptor levels are elevated preceding systemic lupus erythematosus disease flare. Arthritis Rheumatol. 2014 Jul; 66(7):1888-99.
Score: 0.274
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Clinical perspectives on lupus genetics: advances and opportunities. Rheum Dis Clin North Am. 2014 Aug; 40(3):413-32, vii.
Score: 0.273
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New perspectives and insights to Asian systemic lupus erythematosus: renal disease, genetic predisposition and disease activity. Int J Rheum Dis. 2013 Dec; 16(6):611-4.
Score: 0.263
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Comparison of autoantibody specificities between traditional and bead-based assays in a large, diverse collection of patients with systemic lupus erythematosus and family members. Arthritis Rheum. 2012 Nov; 64(11):3677-86.
Score: 0.244
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Lupus and Epstein-Barr. Curr Opin Rheumatol. 2012 Jul; 24(4):383-8.
Score: 0.239
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Influenza vaccination can induce new-onset anticardiolipins but not ß2-glycoprotein-I antibodies among patients with systemic lupus erythematosus. Lupus. 2012 Feb; 21(2):168-74.
Score: 0.232
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B lymphocyte stimulator levels in systemic lupus erythematosus: higher circulating levels in African American patients and increased production after influenza vaccination in patients with low baseline levels. Arthritis Rheum. 2011 Dec; 63(12):3931-41.
Score: 0.229
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Influenza vaccination responses in human systemic lupus erythematosus: impact of clinical and demographic features. Arthritis Rheum. 2011 Aug; 63(8):2396-406.
Score: 0.224
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Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus. Ann Rheum Dis. 2011 Sep; 70(9):1569-74.
Score: 0.221
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The role of genetic variation near interferon-kappa in systemic lupus erythematosus. J Biomed Biotechnol. 2010; 2010.
Score: 0.208
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Everyone comes from somewhere: systemic lupus erythematosus and Epstein-Barr virus induction of host interferon and humoral anti-Epstein-Barr nuclear antigen 1 immunity. Arthritis Rheum. 2010 Jun; 62(6):1571-5.
Score: 0.207
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Ribosomal P autoantibodies are present before SLE onset and are directed against non-C-terminal peptides. J Mol Med (Berl). 2010 Jul; 88(7):719-27.
Score: 0.205
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Early targets of nuclear RNP humoral autoimmunity in human systemic lupus erythematosus. Arthritis Rheum. 2009 Mar; 60(3):848-59.
Score: 0.190
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Aberrant Epstein-Barr viral infection in systemic lupus erythematosus. Autoimmun Rev. 2009 Feb; 8(4):337-42.
Score: 0.188
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Lupus-like autoantibody development in rabbits and mice after immunization with EBNA-1 fragments. J Autoimmun. 2008 Dec; 31(4):362-71.
Score: 0.185
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Clinical criteria for systemic lupus erythematosus precede diagnosis, and associated autoantibodies are present before clinical symptoms. Arthritis Rheum. 2007 Jul; 56(7):2344-51.
Score: 0.169
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Overlapping features of thrombotic thrombocytopenic purpura and systemic lupus erythematosus. South Med J. 2007 May; 100(5):512-4.
Score: 0.167
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Hydroxychloroquine sulfate treatment is associated with later onset of systemic lupus erythematosus. Lupus. 2007; 16(6):401-9.
Score: 0.163
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Epstein-Barr virus and systemic lupus erythematosus. Curr Opin Rheumatol. 2006 Sep; 18(5):462-7.
Score: 0.159
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Epstein-Barr virus and molecular mimicry in systemic lupus erythematosus. Autoimmunity. 2006 Feb; 39(1):63-70.
Score: 0.153
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An altered immune response to Epstein-Barr nuclear antigen 1 in pediatric systemic lupus erythematosus. Arthritis Rheum. 2006 Jan; 54(1):360-8.
Score: 0.152
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Epstein-Barr virus infection induces lupus autoimmunity. Bull NYU Hosp Jt Dis. 2006; 64(1-2):45-50.
Score: 0.152
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The curiously suspicious: a role for Epstein-Barr virus in lupus. Lupus. 2006; 15(11):768-77.
Score: 0.152
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Humoral antigenic targets of the ribosomal P0 lupus autoantigen are not limited to the carboxyl region. Ann N Y Acad Sci. 2005 Jun; 1051:390-403.
Score: 0.146
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Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry. Nat Med. 2005 Jan; 11(1):85-9.
Score: 0.142
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The prevalence, onset, and clinical significance of antiphospholipid antibodies prior to diagnosis of systemic lupus erythematosus. Arthritis Rheum. 2004 Apr; 50(4):1226-32.
Score: 0.135
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Structural availability influences the capacity of autoantigenic epitopes to induce a widespread lupus-like autoimmune response. Proc Natl Acad Sci U S A. 2004 Mar 09; 101(10):3551-6.
Score: 0.134
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Ancestry-based differences in the immune phenotype are associated with lupus activity. JCI Insight. 2023 08 22; 8(16).
Score: 0.129
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Peptide mimics of a major lupus epitope of SmB/B'. Ann N Y Acad Sci. 2003 Apr; 987:215-29.
Score: 0.126
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Genetic load in incomplete lupus erythematosus. Lupus Sci Med. 2023 01; 10(1).
Score: 0.124
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Selective small antigenic structures are capable of inducing widespread autoimmunity which closely mimics the humoral fine specificity of human SLE. Scand J Immunol. 2002 Oct; 56(4):399-407.
Score: 0.121
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Loss-of-function variants in SAT1 cause X-linked childhood-onset systemic lupus erythematosus. Ann Rheum Dis. 2022 Dec; 81(12):1712-1721.
Score: 0.120
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Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus. Front Immunol. 2022; 13:881332.
Score: 0.119
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A High Prevalence of Anti-EBNA1 Heteroantibodies in Systemic Lupus Erythematosus (SLE) Supports Anti-EBNA1 as an Origin for SLE Autoantibodies. Front Immunol. 2022; 13:830993.
Score: 0.116
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Anti-sm autoantibodies in systemic lupus target highly basic surface structures of complexed spliceosomal autoantigens. J Immunol. 2002 Feb 15; 168(4):2054-62.
Score: 0.116
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Impact of glucocorticoids on the incidence of lupus-related major organ damage: a systematic literature review and meta-regression analysis of longitudinal observational studies. Lupus Sci Med. 2021 12; 8(1).
Score: 0.115
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Lupus Susceptibility Region Containing CDKN1B rs34330 Mechanistically Influences Expression and Function of Multiple Target Genes, Also Linked to Proliferation and Apoptosis. Arthritis Rheumatol. 2021 12; 73(12):2303-2313.
Score: 0.114
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The role of Epstein-Barr virus in systemic lupus erythematosus. Front Biosci. 2001 Oct 01; 6:E137-47.
Score: 0.113
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Associations Between Smoking and Systemic Lupus Erythematosus-Related Cytokines and Chemokines Among US Female Nurses. Arthritis Care Res (Hoboken). 2021 11; 73(11):1583-1589.
Score: 0.113
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Role of viruses in systemic lupus erythematosus and Sjögren syndrome. Curr Opin Rheumatol. 2001 Sep; 13(5):370-6.
Score: 0.113
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Lupus autoantibodies recognize the product of an alternative open reading frame of SmB/B'. Biochem Biophys Res Commun. 2001 Aug 03; 285(5):1206-12.
Score: 0.112
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Immune Response to Enterococcus gallinarum in Lupus Patients Is Associated With a Subset of Lupus-Associated Autoantibodies. Front Immunol. 2021; 12:635072.
Score: 0.111
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Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposure. Arthritis Rheum. 2001 May; 44(5):1122-6.
Score: 0.110
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Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus. Genome Biol. 2020 11 19; 21(1):281.
Score: 0.107
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Associations between daily alcohol consumption and systemic lupus erythematosus-related cytokines and chemokines among US female nurses without SLE. Lupus. 2020 Jul; 29(8):976-982.
Score: 0.103
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Cell-bound complement activation products associate with lupus severity in SLE. Lupus Sci Med. 2020 04; 7(1).
Score: 0.102
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Lupus patient decisions about clinical trial participation: a qualitative evaluation of perceptions, facilitators and barriers. Lupus Sci Med. 2020; 7(1):e000360.
Score: 0.102
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Immunization as a model for systemic lupus erythematosus. Semin Arthritis Rheum. 1999 Dec; 29(3):140-7.
Score: 0.100
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Shared early autoantibody recognition events in the development of anti-Sm B/B' in human lupus. Scand J Immunol. 1999 Nov; 50(5):447-55.
Score: 0.099
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Mock Recruitment for the Study of Antimalarials in an Incomplete Lupus Erythematosus Trial. Arthritis Care Res (Hoboken). 2019 11; 71(11):1425-1429.
Score: 0.099
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PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21. JCI Insight. 2019 10 17; 4(20).
Score: 0.099
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Novel genetic associations with interferon in systemic lupus erythematosus identified by replication and fine-mapping of trait-stratified genome-wide screen. Cytokine. 2020 08; 132:154631.
Score: 0.094
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Study of Anti-Malarials in Incomplete Lupus Erythematosus (SMILE): study protocol for a randomized controlled trial. Trials. 2018 Dec 20; 19(1):694.
Score: 0.093
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Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans. Hum Mol Genet. 2018 11 01; 27(21):3813-3824.
Score: 0.093
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ARID3a gene profiles are strongly associated with human interferon alpha production. J Autoimmun. 2019 01; 96:158-167.
Score: 0.092
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A limited lupus anti-spliceosomal response targets a cross-reactive, proline-rich motif. J Autoimmun. 1998 Oct; 11(5):431-8.
Score: 0.092
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A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus. Hum Mol Genet. 2018 07 01; 27(13):2392-2404.
Score: 0.090
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Antibodies to periodontogenic bacteria are associated with higher disease activity in lupus patients. Clin Exp Rheumatol. 2019 Jan-Feb; 37(1):106-111.
Score: 0.090
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Lupus humoral autoimmunity induced in a primate model by short peptide immunization. J Investig Med. 1998 Feb; 46(2):58-65.
Score: 0.088
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A model of peptide-induced lupus autoimmune B cell epitope spreading is strain specific and is not H-2 restricted in mice. J Immunol. 1998 Jan 01; 160(1):502-8.
Score: 0.087
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An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus. J Clin Invest. 1997 Dec 15; 100(12):3019-26.
Score: 0.087
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Transancestral mapping and genetic load in systemic lupus erythematosus. Nat Commun. 2017 07 17; 8:16021.
Score: 0.085
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The Biomarkers of Lupus Disease Study: A Bold Approach May Mitigate Interference of Background Immunosuppressants in Clinical Trials. Arthritis Rheumatol. 2017 06; 69(6):1257-1266.
Score: 0.084
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Lupus humoral autoimmunity after short peptide immunization. Ann N Y Acad Sci. 1997 Apr 05; 815:124-7.
Score: 0.083
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Association of IFIH1 and pro-inflammatory mediators: Potential new clues in SLE-associated pathogenesis. PLoS One. 2017; 12(2):e0171193.
Score: 0.082
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Impact of heart rate variability, a marker for cardiac health, on lupus disease activity. Arthritis Res Ther. 2016 09 02; 18:197.
Score: 0.080
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Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus. Ann Rheum Dis. 2017 Jan; 76(1):153-158.
Score: 0.078
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Human lupus anti-spliceosome A protein autoantibodies bind contiguous surface structures and segregate into two sequential epitope binding patterns. J Immunol. 1996 May 15; 156(10):4018-26.
Score: 0.078
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X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome. Arthritis Rheumatol. 2016 05; 68(5):1290-1300.
Score: 0.078
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Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture. Arthritis Rheumatol. 2016 Apr; 68(4):932-43.
Score: 0.077
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Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production. Ann Rheum Dis. 2016 Nov; 75(11):2007-2013.
Score: 0.076
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Autoepitopes in lupus. J Lab Clin Med. 1995 Dec; 126(6):509-16.
Score: 0.076
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Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus. Clin Immunol. 2015 Dec; 161(2):157-62.
Score: 0.075
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Genetics of Lupus Nephritis: Clinical Implications. Semin Nephrol. 2015 Sep; 35(5):396-409.
Score: 0.074
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High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination. PLoS One. 2015; 10(5):e0125618.
Score: 0.073
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Peptide autoantigenicity of the small nuclear ribonucleoprotein C. Clin Exp Rheumatol. 1995 May-Jun; 13(3):299-305.
Score: 0.073
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Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression. Am J Hum Genet. 2015 May 07; 96(5):731-9.
Score: 0.072
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Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B'-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity. J Exp Med. 1995 Feb 01; 181(2):453-61.
Score: 0.071
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Differential expression of the transcription factor ARID3a in lupus patient hematopoietic progenitor cells. J Immunol. 2015 Feb 01; 194(3):940-9.
Score: 0.071
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Sequential autoantigenic determinants of the small nuclear ribonucleoprotein Sm D shared by human lupus autoantibodies and MRL lpr/lpr antibodies. Clin Exp Immunol. 1994 Dec; 98(3):419-26.
Score: 0.071
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Disease activity in systemic lupus erythematosus correlates with expression of the transcription factor AT-rich-interactive domain 3A. Arthritis Rheumatol. 2014 Dec; 66(12):3404-12.
Score: 0.071
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Association of systemic lupus erythematosus with uranium exposure in a community living near a uranium-processing plant: a nested case-control study. Arthritis Rheumatol. 2014 Nov; 66(11):3105-12.
Score: 0.070
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The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share. Hum Mol Genet. 2015 Jan 15; 24(2):582-96.
Score: 0.069
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Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA. Ann Rheum Dis. 2016 Jan; 75(1):242-52.
Score: 0.069
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How should lupus flares be measured? Deconstruction of the safety of estrogen in lupus erythematosus national assessment-systemic lupus erythematosus disease activity index flare index. Rheumatology (Oxford). 2014 Dec; 53(12):2175-81.
Score: 0.068
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Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription. Am J Hum Genet. 2014 Apr 03; 94(4):586-98.
Score: 0.067
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Prolidase deficiency breaks tolerance to lupus-associated antigens. Int J Rheum Dis. 2013 Dec; 16(6):674-80.
Score: 0.066
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Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations. Hum Mol Genet. 2014 Mar 15; 23(6):1656-68.
Score: 0.065
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Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression. PLoS Genet. 2013; 9(10):e1003870.
Score: 0.065
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Familial aggregation of high tumor necrosis factor alpha levels in systemic lupus erythematosus. Clin Dev Immunol. 2013; 2013:267430.
Score: 0.065
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Herpes zoster vaccination in SLE: a pilot study of immunogenicity. J Rheumatol. 2013 Nov; 40(11):1875-80.
Score: 0.065
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Evidence of dynamically dysregulated gene expression pathways in hyperresponsive B cells from African American lupus patients. PLoS One. 2013; 8(8):e71397.
Score: 0.065
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PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes. PLoS One. 2013; 8(8):e69404.
Score: 0.064
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Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4. PLoS Genet. 2013; 9(7):e1003554.
Score: 0.064
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Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry. J Rheumatol. 2013 Jun; 40(6):842-9.
Score: 0.063
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MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus. PLoS Genet. 2013; 9(2):e1003336.
Score: 0.063
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Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse. J Autoimmun. 2013 Mar; 41:168-74.
Score: 0.062
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Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production. PLoS Genet. 2013; 9(2):e1003222.
Score: 0.062
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Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus. Arthritis Rheum. 2012 Nov; 64(11):3695-705.
Score: 0.061
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Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations. Arthritis Rheum. 2012 Nov; 64(11):3687-94.
Score: 0.061
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Large-scale analysis of tumor necrosis factor a levels in systemic lupus erythematosus. Arthritis Rheum. 2012 Sep; 64(9):2947-52.
Score: 0.060
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Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups. Ann Rheum Dis. 2013 Mar; 72(3):437-44.
Score: 0.060
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Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries. Ann Rheum Dis. 2012 Nov; 71(11):1809-14.
Score: 0.059
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A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus. Genes Immun. 2012 Jul; 13(5):380-7.
Score: 0.059
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Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study. Am J Hum Genet. 2012 Apr 06; 90(4):648-60.
Score: 0.059
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Effects of IRF5 lupus risk haplotype on pathways predicted to influence B cell functions. J Biomed Biotechnol. 2012; 2012:594056.
Score: 0.058
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Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus. Arthritis Rheum. 2012 Feb; 64(2):485-92.
Score: 0.058
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Evaluation of TRAF6 in a large multiancestral lupus cohort. Arthritis Rheum. 2012 Jun; 64(6):1960-9.
Score: 0.058
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Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus. Ann Rheum Dis. 2012 May; 71(5):694-9.
Score: 0.057
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IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus. Ann Rheum Dis. 2012 Mar; 71(3):463-8.
Score: 0.057
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Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study. Arthritis Rheum. 2011 Nov; 63(11):3493-501.
Score: 0.057
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Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK. Ann Rheum Dis. 2012 Jan; 71(1):136-42.
Score: 0.057
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Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups. Arthritis Rheum. 2011 Sep; 63(9):2755-63.
Score: 0.056
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Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus. Ann Rheum Dis. 2011 Oct; 70(10):1752-7.
Score: 0.056
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Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21. Arthritis Rheum. 2011 Jun; 63(6):1689-97.
Score: 0.055
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Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility. PLoS Genet. 2011 May; 7(5):e1002079.
Score: 0.055
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Network analysis of associations between serum interferon-a activity, autoantibodies, and clinical features in systemic lupus erythematosus. Arthritis Rheum. 2011 Apr; 63(4):1044-53.
Score: 0.055
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Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus. Nat Genet. 2011 Mar; 43(3):253-8.
Score: 0.054
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Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort. Genes Immun. 2011 Jun; 12(4):270-9.
Score: 0.054
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Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study. Am J Hum Genet. 2011 Jan 07; 88(1):83-91.
Score: 0.054
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The lupus family registry and repository. Rheumatology (Oxford). 2011 Jan; 50(1):47-59.
Score: 0.053
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Polymorphisms in the Hsp70 gene locus are genetically associated with systemic lupus erythematosus. Ann Rheum Dis. 2010 Nov; 69(11):1983-9.
Score: 0.052
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Male-only systemic lupus. J Rheumatol. 2010 Jul; 37(7):1480-7.
Score: 0.052
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60 kD Ro and nRNP A frequently initiate human lupus autoimmunity. PLoS One. 2010 Mar 10; 5(3):e9599.
Score: 0.051
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ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry. Ann Rheum Dis. 2010 Jul; 69(7):1329-32.
Score: 0.050
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A polymorphism within IL21R confers risk for systemic lupus erythematosus. Arthritis Rheum. 2009 Aug; 60(8):2402-7.
Score: 0.049
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Evaluation of C1q genomic region in minority racial groups of lupus. Genes Immun. 2009 Jul; 10(5):517-24.
Score: 0.048
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Genetic associations of LYN with systemic lupus erythematosus. Genes Immun. 2009 Jul; 10(5):397-403.
Score: 0.048
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Replication of the BANK1 genetic association with systemic lupus erythematosus in a European-derived population. Genes Immun. 2009 Jul; 10(5):531-8.
Score: 0.048
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Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus. Arthritis Rheum. 2009 Apr; 60(4):1076-84.
Score: 0.048
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High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups. Arthritis Rheum. 2009 Apr; 60(4):1085-95.
Score: 0.048
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Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE). Hum Mol Genet. 2009 Mar 15; 18(6):1171-80.
Score: 0.047
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Patients with familial and sporadic onset SLE have similar clinical profiles but vary profoundly by race. Lupus. 2008 Nov; 17(11):1004-9.
Score: 0.046
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Recent advances and opportunities in research on lupus: environmental influences and mechanisms of disease. Environ Health Perspect. 2008 Jun; 116(6):695-702.
Score: 0.045
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Autoantibody prevalence and lupus characteristics in a unique African American population. Arthritis Rheum. 2008 May; 58(5):1237-47.
Score: 0.045
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Osteopontin and systemic lupus erythematosus association: a probable gene-gender interaction. PLoS One. 2008 Mar 12; 3(3):e0001757.
Score: 0.044
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Common variants within MECP2 confer risk of systemic lupus erythematosus. PLoS One. 2008 Mar 05; 3(3):e1727.
Score: 0.044
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Interferon regulatory factor-5 is genetically associated with systemic lupus erythematosus in African Americans. Genes Immun. 2008 Apr; 9(3):187-94.
Score: 0.044
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Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet. 2008 Feb; 40(2):204-10.
Score: 0.044
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A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus. Nat Genet. 2008 Feb; 40(2):152-4.
Score: 0.044
-
Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus. Ann Rheum Dis. 2008 Apr; 67(4):458-61.
Score: 0.043
-
Evaluation of the genetic association of the PTPN22 R620W polymorphism in familial and sporadic systemic lupus erythematosus. Arthritis Rheum. 2006 Aug; 54(8):2533-40.
Score: 0.040
-
Modification of lupus-associated 60-kDa Ro protein with the lipid oxidation product 4-hydroxy-2-nonenal increases antigenicity and facilitates epitope spreading. Free Radic Biol Med. 2005 Mar 15; 38(6):719-28.
Score: 0.036
-
Disease diagnostics using machine learning of B cell and T cell receptor sequences. Science. 2025 Feb 21; 387(6736):eadp2407.
Score: 0.036
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Systemic lupus erythematosus (SLE) and chromosome 16: confirmation of linkage to 16q12-13 and evidence for genetic heterogeneity. Eur J Hum Genet. 2004 Aug; 12(8):668-72.
Score: 0.034
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Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med. 2003 Oct 16; 349(16):1526-33.
Score: 0.033
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Infectious mononucleosis patients temporarily recognize a unique, cross-reactive epitope of Epstein-Barr virus nuclear antigen-1. J Med Virol. 2003 Jun; 70(2):253-7.
Score: 0.032
-
Rapid clinical progression to diagnosis among African-American men with systemic lupus erythematosus. Lupus. 2003; 12(2):99-106.
Score: 0.031
-
Anti-Ro and anti-nRNP response in unaffected family members of SLE patients. Lupus. 2003; 12(4):335-7.
Score: 0.031
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Stratification of pedigrees multiplex for systemic lupus erythematosus and for self-reported rheumatoid arthritis detects a systemic lupus erythematosus susceptibility gene (SLER1) at 5p15.3. Arthritis Rheum. 2002 Nov; 46(11):2937-45.
Score: 0.031
-
Genetic linkage of systemic lupus erythematosus with chromosome 11q14 (SLEH1) in African-American families stratified by a nucleolar antinuclear antibody pattern. Genes Immun. 2002 Oct; 3 Suppl 1:S31-4.
Score: 0.030
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Genome scan stratified by the presence of anti-double-stranded DNA (dsDNA) autoantibody in pedigrees multiplex for systemic lupus erythematosus (SLE) establishes linkages at 19p13.2 (SLED1) and 18q21.1 (SLED2). Genes Immun. 2002 Oct; 3 Suppl 1:S35-41.
Score: 0.030
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The genetics of systemic lupus erythematosus stratified by renal disease: linkage at 10q22.3 (SLEN1), 2q34-35 (SLEN2), and 11p15.6 (SLEN3). Genes Immun. 2002 Oct; 3 Suppl 1:S57-62.
Score: 0.030
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And Yet It Moves: Oxidation of the Nuclear Autoantigen La/SS-B Is the Driving Force for Nucleo-Cytoplasmic Shuttling. Int J Mol Sci. 2021 Sep 08; 22(18).
Score: 0.028
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Development of anti-dsDNA autoantibodies prior to clinical diagnosis of systemic lupus erythematosus. Scand J Immunol. 2001 Jul-Aug; 54(1-2):211-9.
Score: 0.028
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Two Be or Not Two Be: The Nuclear Autoantigen La/SS-B Is Able to Form Dimers and Oligomers in a Redox Dependent Manner. Int J Mol Sci. 2021 Mar 25; 22(7).
Score: 0.027
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Top-down Mass Spectrometry Analysis of Human Serum Autoantibody Antigen-Binding Fragments. Sci Rep. 2019 02 20; 9(1):2345.
Score: 0.024
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Prevalence of autoantibodies to ribosomal P proteins in juvenile-onset systemic lupus erythematosus compared with the adult disease. Arthritis Rheum. 1999 Jan; 42(1):69-75.
Score: 0.023
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Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome 1q in African-American pedigrees. Proc Natl Acad Sci U S A. 1998 Dec 08; 95(25):14869-74.
Score: 0.023
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B-cell epitope spreading in autoimmunity. Immunol Rev. 1998 Aug; 164:185-200.
Score: 0.023
-
Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity. Elife. 2016 Feb 15; 5.
Score: 0.019
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Antibody quantity versus quality after influenza vaccination. Vaccine. 2009 Oct 23; 27(45):6358-62.
Score: 0.012
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Human B cell subsets. Adv Immunol. 2008; 98:151-224.
Score: 0.011
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Autoimmunity as a result of escape from RNA surveillance. J Immunol. 2006 Aug 01; 177(3):1698-707.
Score: 0.010
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Immunization with peptides from 60 kDa Ro in diverse mouse strains. Scand J Immunol. 2002 Nov; 56(5):477-83.
Score: 0.008
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Immunization with short peptides from the sequence of the systemic lupus erythematosus-associated 60-kDa Ro autoantigen results in anti-Ro ribonucleoprotein autoimmunity. J Immunol. 1996 May 15; 156(10):4059-66.
Score: 0.005