Rodney Tweten to Cholesterol
This is a "connection" page, showing publications Rodney Tweten has written about Cholesterol.
Connection Strength
7.017
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A Key Motif in the Cholesterol-Dependent Cytolysins Reveals a Large Family of Related Proteins. mBio. 2020 09 29; 11(5).
Score: 0.655
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The Cholesterol-dependent Cytolysin Membrane-binding Interface Discriminates Lipid Environments of Cholesterol to Support ß-Barrel Pore Insertion. J Biol Chem. 2015 Jul 17; 290(29):17733-17744.
Score: 0.453
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An intermolecular electrostatic interaction controls the prepore-to-pore transition in a cholesterol-dependent cytolysin. Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7):2204-9.
Score: 0.443
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Mouse, but not human, ApoB-100 lipoprotein cholesterol is a potent innate inhibitor of Streptococcus pneumoniae pneumolysin. PLoS Pathog. 2014 Sep; 10(9):e1004353.
Score: 0.430
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Identification and characterization of the first cholesterol-dependent cytolysins from Gram-negative bacteria. Infect Immun. 2013 Jan; 81(1):216-25.
Score: 0.379
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The cholesterol-dependent cytolysin signature motif: a critical element in the allosteric pathway that couples membrane binding to pore assembly. PLoS Pathog. 2012; 8(7):e1002787.
Score: 0.370
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Packing a punch: the mechanism of pore formation by cholesterol dependent cytolysins and membrane attack complex/perforin-like proteins. Curr Opin Struct Biol. 2012 Jun; 22(3):342-9.
Score: 0.368
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Monomer-monomer interactions propagate structural transitions necessary for pore formation by the cholesterol-dependent cytolysins. J Biol Chem. 2012 Jul 13; 287(29):24534-43.
Score: 0.368
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Membrane assembly of the cholesterol-dependent cytolysin pore complex. Biochim Biophys Acta. 2012 Apr; 1818(4):1028-38.
Score: 0.347
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Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4341-6.
Score: 0.314
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Characterization of a streptococcal cholesterol-dependent cytolysin with a lewis y and b specific lectin domain. Biochemistry. 2008 Jul 08; 47(27):7097-107.
Score: 0.280
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Structural elements of the cholesterol-dependent cytolysins that are responsible for their cholesterol-sensitive membrane interactions. Proc Natl Acad Sci U S A. 2007 Dec 18; 104(51):20226-31.
Score: 0.270
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Specific protein-membrane contacts are required for prepore and pore assembly by a cholesterol-dependent cytolysin. J Biol Chem. 2007 May 25; 282(21):15709-16.
Score: 0.257
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Cholesterol-dependent cytolysins, a family of versatile pore-forming toxins. Infect Immun. 2005 Oct; 73(10):6199-209.
Score: 0.232
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Human CD59 is a receptor for the cholesterol-dependent cytolysin intermedilysin. Nat Struct Mol Biol. 2004 Dec; 11(12):1173-8.
Score: 0.218
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Redefining cholesterol's role in the mechanism of the cholesterol-dependent cytolysins. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11315-20.
Score: 0.201
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Monomer-monomer interactions drive the prepore to pore conversion of a beta-barrel-forming cholesterol-dependent cytolysin. J Biol Chem. 2002 Mar 29; 277(13):11597-605.
Score: 0.179
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How protein engineering has revealed the molecular mechanisms of pore-forming toxins. Methods Enzymol. 2021; 649:47-70.
Score: 0.168
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The cholesterol-dependent cytolysins. Curr Top Microbiol Immunol. 2001; 257:15-33.
Score: 0.167
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The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane beta-hairpins. Biochemistry. 2000 Aug 22; 39(33):10284-93.
Score: 0.163
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Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins. Structure. 2016 09 06; 24(9):1488-98.
Score: 0.123
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The Unique Molecular Choreography of Giant Pore Formation by the Cholesterol-Dependent Cytolysins of Gram-Positive Bacteria. Annu Rev Microbiol. 2015; 69:323-40.
Score: 0.110
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Cholesterol exposure at the membrane surface is necessary and sufficient to trigger perfringolysin O binding. Biochemistry. 2009 May 12; 48(18):3977-87.
Score: 0.074
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Plasma membrane cholesterol content affects nitric oxide diffusion dynamics and signaling. J Biol Chem. 2008 Jul 04; 283(27):18513-21.
Score: 0.069
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Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins. J Mol Biol. 2007 Apr 13; 367(5):1227-36.
Score: 0.063
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Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin. Proc Natl Acad Sci U S A. 2005 Jan 18; 102(3):600-5.
Score: 0.055
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Membrane-dependent conformational changes initiate cholesterol-dependent cytolysin oligomerization and intersubunit beta-strand alignment. Nat Struct Mol Biol. 2004 Aug; 11(8):697-705.
Score: 0.053
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Assembly and topography of the prepore complex in cholesterol-dependent cytolysins. J Biol Chem. 2003 Aug 15; 278(33):31218-25.
Score: 0.049
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Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form. Cell. 1997 May 30; 89(5):685-92.
Score: 0.033
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Stonefish toxin defines an ancient branch of the perforin-like superfamily. Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50):15360-5.
Score: 0.029
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Structural studies of Streptococcus pyogenes streptolysin O provide insights into the early steps of membrane penetration. J Mol Biol. 2014 Feb 20; 426(4):785-92.
Score: 0.026
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Disulfide-bond scanning reveals assembly state and ß-strand tilt angle of the PFO ß-barrel. Nat Chem Biol. 2013 Jun; 9(6):383-9.
Score: 0.024
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Prepore to pore transition of a cholesterol-dependent cytolysin visualized by electron microscopy. J Struct Biol. 2005 Apr; 150(1):100-8.
Score: 0.014
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Structural insights into the membrane-anchoring mechanism of a cholesterol-dependent cytolysin. Nat Struct Biol. 2002 Nov; 9(11):823-7.
Score: 0.012
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Mechanism of membrane insertion of a multimeric beta-barrel protein: perfringolysin O creates a pore using ordered and coupled conformational changes. Mol Cell. 2000 Nov; 6(5):1233-42.
Score: 0.010
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The molecular mechanism of pneumolysin, a virulence factor from Streptococcus pneumoniae. J Mol Biol. 1998 Nov 27; 284(2):449-61.
Score: 0.009