Rodney Tweten to Animals
This is a "connection" page, showing publications Rodney Tweten has written about Animals.
Connection Strength
0.695
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Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria. Nat Commun. 2024 Jun 12; 15(1):5028.
Score: 0.089
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How protein engineering has revealed the molecular mechanisms of pore-forming toxins. Methods Enzymol. 2021; 649:47-70.
Score: 0.071
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A Key Motif in the Cholesterol-Dependent Cytolysins Reveals a Large Family of Related Proteins. mBio. 2020 09 29; 11(5).
Score: 0.069
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The Cholesterol-dependent Cytolysin Membrane-binding Interface Discriminates Lipid Environments of Cholesterol to Support ß-Barrel Pore Insertion. J Biol Chem. 2015 Jul 17; 290(29):17733-17744.
Score: 0.048
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Mouse, but not human, ApoB-100 lipoprotein cholesterol is a potent innate inhibitor of Streptococcus pneumoniae pneumolysin. PLoS Pathog. 2014 Sep; 10(9):e1004353.
Score: 0.045
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Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8alpha and C9. J Biol Chem. 2011 Jun 10; 286(23):20952-62.
Score: 0.036
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Human CD59 is a receptor for the cholesterol-dependent cytolysin intermedilysin. Nat Struct Mol Biol. 2004 Dec; 11(12):1173-8.
Score: 0.023
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Mapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):13803-8.
Score: 0.021
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Pore-forming activity of S. pneumoniae pneumolysin disrupts the paracellular localization of the epithelial adherens junction protein E-cadherin. Infect Immun. 2023 09 14; 91(9):e0021323.
Score: 0.021
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Clostridium perfringens beta-toxin forms potential-dependent, cation-selective channels in lipid bilayers. Infect Immun. 2000 Oct; 68(10):5546-51.
Score: 0.017
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A listeriolysin O subunit vaccine is protective against Listeria monocytogenes. Vaccine. 2020 08 10; 38(36):5803-5813.
Score: 0.017
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Immunotherapy targeting the Streptococcus pyogenes M protein or streptolysin O to treat or prevent influenza A superinfection. PLoS One. 2020; 15(6):e0235139.
Score: 0.017
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Preclinical in vitro and in vivo profile of a highly-attenuated, broadly efficacious pneumolysin genetic toxoid. Vaccine. 2021 03 12; 39(11):1652-1660.
Score: 0.017
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Pneumolysin Induces 12-Lipoxygenase-Dependent Neutrophil Migration during Streptococcus pneumoniae Infection. J Immunol. 2020 01 01; 204(1):101-111.
Score: 0.016
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Clostridium septicum alpha-toxin is proteolytically activated by furin. Infect Immun. 1997 Oct; 65(10):4130-4.
Score: 0.014
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Stonefish toxin defines an ancient branch of the perforin-like superfamily. Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50):15360-5.
Score: 0.012
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Multivalent Pneumococcal Protein Vaccines Comprising Pneumolysoid with Epitopes/Fragments of CbpA and/or PspA Elicit Strong and Broad Protection. Clin Vaccine Immunol. 2015 Oct; 22(10):1079-89.
Score: 0.012
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Perfringolysin O: The Underrated Clostridium perfringens Toxin? Toxins (Basel). 2015 May 14; 7(5):1702-21.
Score: 0.012
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Conformational changes during pore formation by the perforin-related protein pleurotolysin. PLoS Biol. 2015 Feb; 13(2):e1002049.
Score: 0.012
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Cardiac myocyte dysfunction induced by streptolysin O is membrane pore and calcium dependent. Shock. 2015 Feb; 43(2):178-84.
Score: 0.012
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The impact of pneumolysin on the macrophage response to Streptococcus pneumoniae is strain-dependent. PLoS One. 2014; 9(8):e103625.
Score: 0.011
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Broadly protective protein-based pneumococcal vaccine composed of pneumolysin toxoid-CbpA peptide recombinant fusion protein. J Infect Dis. 2014 Apr 01; 209(7):1116-25.
Score: 0.011
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Purification and characterization of the lethal toxin (alpha-toxin) of Clostridium septicum. Infect Immun. 1992 Mar; 60(3):784-90.
Score: 0.010
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Intermedilysin-receptor interactions during assembly of the pore complex: assembly intermediates increase host cell susceptibility to complement-mediated lysis. J Biol Chem. 2009 May 08; 284(19):12719-26.
Score: 0.008
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Pore-forming activity of alpha-toxin is essential for clostridium septicum-mediated myonecrosis. Infect Immun. 2009 Mar; 77(3):943-51.
Score: 0.008
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Purification and characterization of toxin B from Clostridium difficile. Infect Immun. 1988 Jul; 56(7):1708-14.
Score: 0.007
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Rapid conditional targeted ablation of cells expressing human CD59 in transgenic mice by intermedilysin. Nat Med. 2008 Jan; 14(1):98-103.
Score: 0.007
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Cytotoxic activity of Bacillus anthracis protective antigen observed in a macrophage cell line overexpressing ANTXR1. Cell Microbiol. 2006 Aug; 8(8):1272-81.
Score: 0.006
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Intracellular glycosylphosphatidylinositols accumulate on endosomes: toxicity of alpha-toxin to Leishmania major. Eukaryot Cell. 2005 Mar; 4(3):556-66.
Score: 0.006
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Endosomes, glycosomes, and glycosylphosphatidylinositol catabolism in Leishmania major. J Biol Chem. 2004 Oct 01; 279(40):42106-13.
Score: 0.006
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Clostridium septicum alpha-toxin is active against the parasitic protozoan Toxoplasma gondii and targets members of the SAG family of glycosylphosphatidylinositol-anchored surface proteins. Infect Immun. 2002 Aug; 70(8):4353-61.
Score: 0.005
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Beta-barrel pore-forming toxins: intriguing dimorphic proteins. Biochemistry. 2001 Aug 07; 40(31):9065-73.
Score: 0.005
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Clostridium septicum alpha toxin uses glycosylphosphatidylinositol-anchored protein receptors. J Biol Chem. 1999 Sep 17; 274(38):27274-80.
Score: 0.004
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Expression and properties of an aerolysin--Clostridium septicum alpha toxin hybrid protein. Mol Microbiol. 1999 Feb; 31(3):785-94.
Score: 0.004
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Clostridial gas gangrene: evidence that alpha and theta toxins differentially modulate the immune response and induce acute tissue necrosis. J Infect Dis. 1997 Jul; 176(1):189-95.
Score: 0.003
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Effects of Clostridium perfringens recombinant and crude phospholipase C and theta-toxin on rabbit hemodynamic parameters. J Infect Dis. 1995 Nov; 172(5):1317-23.
Score: 0.003
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Efficient gene delivery and expression in mammalian cells using DNA coupled with perfringolysin O. Gene Ther. 1995 Sep; 2(7):498-503.
Score: 0.003
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Clostridium perfringens invasiveness is enhanced by effects of theta toxin upon PMNL structure and function: the roles of leukocytotoxicity and expression of CD11/CD18 adherence glycoprotein. FEMS Immunol Med Microbiol. 1993 Dec; 7(4):321-36.
Score: 0.003
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Capacity of listeriolysin O, streptolysin O, and perfringolysin O to mediate growth of Bacillus subtilis within mammalian cells. Infect Immun. 1992 Jul; 60(7):2710-7.
Score: 0.002
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Ionic interactions between proteins in nonequilibrium pH gradient electrophoresis: histones affect the migration of high mobility group nonhistone chromatin proteins. Anal Biochem. 1983 Jul 15; 132(2):294-304.
Score: 0.001