Rodney Tweten to Bacterial Proteins
This is a "connection" page, showing publications Rodney Tweten has written about Bacterial Proteins.
Connection Strength
2.113
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Structural elements of the cholesterol-dependent cytolysins that are responsible for their cholesterol-sensitive membrane interactions. Proc Natl Acad Sci U S A. 2007 Dec 18; 104(51):20226-31.
Score: 0.219
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Specific protein-membrane contacts are required for prepore and pore assembly by a cholesterol-dependent cytolysin. J Biol Chem. 2007 May 25; 282(21):15709-16.
Score: 0.209
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Human CD59 is a receptor for the cholesterol-dependent cytolysin intermedilysin. Nat Struct Mol Biol. 2004 Dec; 11(12):1173-8.
Score: 0.177
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Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria. Nat Commun. 2024 Jun 12; 15(1):5028.
Score: 0.172
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A proteolytically activated antimicrobial toxin encoded on a mobile plasmid of Bacteroidales induces a protective response. Nat Commun. 2022 07 23; 13(1):4258.
Score: 0.151
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Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins. Structure. 2016 09 06; 24(9):1488-98.
Score: 0.100
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Multivalent Pneumococcal Protein Vaccines Comprising Pneumolysoid with Epitopes/Fragments of CbpA and/or PspA Elicit Strong and Broad Protection. Clin Vaccine Immunol. 2015 Oct; 22(10):1079-89.
Score: 0.093
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The Cholesterol-dependent Cytolysin Membrane-binding Interface Discriminates Lipid Environments of Cholesterol to Support ß-Barrel Pore Insertion. J Biol Chem. 2015 Jul 17; 290(29):17733-17744.
Score: 0.092
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An intermolecular electrostatic interaction controls the prepore-to-pore transition in a cholesterol-dependent cytolysin. Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7):2204-9.
Score: 0.090
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Mouse, but not human, ApoB-100 lipoprotein cholesterol is a potent innate inhibitor of Streptococcus pneumoniae pneumolysin. PLoS Pathog. 2014 Sep; 10(9):e1004353.
Score: 0.087
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Broadly protective protein-based pneumococcal vaccine composed of pneumolysin toxoid-CbpA peptide recombinant fusion protein. J Infect Dis. 2014 Apr 01; 209(7):1116-25.
Score: 0.082
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The cholesterol-dependent cytolysin signature motif: a critical element in the allosteric pathway that couples membrane binding to pore assembly. PLoS Pathog. 2012; 8(7):e1002787.
Score: 0.075
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Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity. Structure. 2012 Feb 08; 20(2):248-58.
Score: 0.073
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Purification and characterization of toxin B from Clostridium difficile. Infect Immun. 1988 Jul; 56(7):1708-14.
Score: 0.057
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Rapid conditional targeted ablation of cells expressing human CD59 in transgenic mice by intermedilysin. Nat Med. 2008 Jan; 14(1):98-103.
Score: 0.055
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Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin. Proc Natl Acad Sci U S A. 2005 Jan 18; 102(3):600-5.
Score: 0.045
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Crystallization and preliminary X-ray analysis of the human-specific toxin intermedilysin. Acta Crystallogr D Biol Crystallogr. 2004 Feb; 60(Pt 2):347-9.
Score: 0.042
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Pore-forming activity of S. pneumoniae pneumolysin disrupts the paracellular localization of the epithelial adherens junction protein E-cadherin. Infect Immun. 2023 09 14; 91(9):e0021323.
Score: 0.041
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Immunotherapy targeting the Streptococcus pyogenes M protein or streptolysin O to treat or prevent influenza A superinfection. PLoS One. 2020; 15(6):e0235139.
Score: 0.033
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Preclinical in vitro and in vivo profile of a highly-attenuated, broadly efficacious pneumolysin genetic toxoid. Vaccine. 2021 03 12; 39(11):1652-1660.
Score: 0.033
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Pneumolysin Induces 12-Lipoxygenase-Dependent Neutrophil Migration during Streptococcus pneumoniae Infection. J Immunol. 2020 01 01; 204(1):101-111.
Score: 0.031
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Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation. Sci Rep. 2015 Sep 25; 5:14352.
Score: 0.023
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Cardiac myocyte dysfunction induced by streptolysin O is membrane pore and calcium dependent. Shock. 2015 Feb; 43(2):178-84.
Score: 0.022
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The impact of pneumolysin on the macrophage response to Streptococcus pneumoniae is strain-dependent. PLoS One. 2014; 9(8):e103625.
Score: 0.022
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Structural studies of Streptococcus pyogenes streptolysin O provide insights into the early steps of membrane penetration. J Mol Biol. 2014 Feb 20; 426(4):785-92.
Score: 0.021
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The pore-forming toxin listeriolysin O mediates a novel entry pathway of L. monocytogenes into human hepatocytes. PLoS Pathog. 2011 Nov; 7(11):e1002356.
Score: 0.018
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Nucleotide sequence of the gene for perfringolysin O (theta-toxin) from Clostridium perfringens: significant homology with the genes for streptolysin O and pneumolysin. Infect Immun. 1988 Dec; 56(12):3235-40.
Score: 0.015
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Assembly and topography of the prepore complex in cholesterol-dependent cytolysins. J Biol Chem. 2003 Aug 15; 278(33):31218-25.
Score: 0.010
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Purification and partial characterization of a putative precursor to staphylococcal enterotoxin B. Infect Immun. 1981 Dec; 34(3):900-7.
Score: 0.009
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Self-interaction of pneumolysin, the pore-forming protein toxin of Streptococcus pneumoniae. J Mol Biol. 1998 Dec 11; 284(4):1223-37.
Score: 0.007
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The molecular mechanism of pneumolysin, a virulence factor from Streptococcus pneumoniae. J Mol Biol. 1998 Nov 27; 284(2):449-61.
Score: 0.007
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Capacity of listeriolysin O, streptolysin O, and perfringolysin O to mediate growth of Bacillus subtilis within mammalian cells. Infect Immun. 1992 Jul; 60(7):2710-7.
Score: 0.005