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Courtney Houchen to Animals

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This is a "connection" page, showing publications Courtney Houchen has written about Animals.
Courtney Houchen
Connection Strength
1.751
Animals
  1. Evolving insights into pancreatic tumor initiation and progression through DCLK1-expressing tuft cells. Dev Cell. 2025 Mar 24; 60(6):817-818.
    View in: PubMed
    Score: 0.091
  2. Tuft Cells Play Critical Roles in the Heterogeneity and Epithelial Plasticity in Pancreatic Cancer Initiation and Progression. Gastroenterology. 2020 11; 159(5):1657-1659.
    View in: PubMed
    Score: 0.067
  3. Doublecortin-like kinase 1 promotes hepatocyte clonogenicity and oncogenic programming via non-canonical ß-catenin-dependent mechanism. Sci Rep. 2020 06 29; 10(1):10578.
    View in: PubMed
    Score: 0.066
  4. DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization. Mol Cancer Ther. 2020 07; 19(7):1539-1549.
    View in: PubMed
    Score: 0.065
  5. Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer. Int J Cancer. 2018 09 01; 143(5):1162-1175.
    View in: PubMed
    Score: 0.057
  6. Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells. Mol Cancer. 2017 02 01; 16(1):30.
    View in: PubMed
    Score: 0.052
  7. Intestinal tuft cells regulate the ATM mediated DNA Damage response via Dclk1 dependent mechanism for crypt restitution following radiation injury. Sci Rep. 2016 11 23; 6:37667.
    View in: PubMed
    Score: 0.051
  8. Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism. Oncotarget. 2015 Nov 10; 6(35):37200-15.
    View in: PubMed
    Score: 0.048
  9. Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewal. Oncotarget. 2015 Oct 13; 6(31):30876-86.
    View in: PubMed
    Score: 0.048
  10. Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases. Oncotarget. 2015 Aug 21; 6(24):20327-44.
    View in: PubMed
    Score: 0.047
  11. Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis. PLoS One. 2015; 10(8):e0134212.
    View in: PubMed
    Score: 0.047
  12. Dietary Pectin Increases Intestinal Crypt Stem Cell Survival following Radiation Injury. PLoS One. 2015; 10(8):e0135561.
    View in: PubMed
    Score: 0.047
  13. Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells. PLoS One. 2015; 10(2):e0118933.
    View in: PubMed
    Score: 0.046
  14. DCLK1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition. Oncotarget. 2014 Oct 15; 5(19):9269-80.
    View in: PubMed
    Score: 0.044
  15. XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism. Cancer Lett. 2014 Aug 28; 351(1):151-61.
    View in: PubMed
    Score: 0.043
  16. Brief report: Dclk1 deletion in tuft cells results in impaired epithelial repair after radiation injury. Stem Cells. 2014 Mar; 32(3):822-7.
    View in: PubMed
    Score: 0.042
  17. Inhibition of Notch signaling reduces the number of surviving Dclk1+ reserve crypt epithelial stem cells following radiation injury. Am J Physiol Gastrointest Liver Physiol. 2014 Mar 01; 306(5):G404-11.
    View in: PubMed
    Score: 0.042
  18. DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer. PLoS One. 2013; 8(9):e73940.
    View in: PubMed
    Score: 0.041
  19. Hepatitis C virus-induced cancer stem cell-like signatures in cell culture and murine tumor xenografts. J Virol. 2011 Dec; 85(23):12292-303.
    View in: PubMed
    Score: 0.036
  20. Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism. J Nanobiotechnology. 2011 Sep 19; 9:40.
    View in: PubMed
    Score: 0.036
  21. DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism. Cancer Res. 2011 Mar 15; 71(6):2328-38.
    View in: PubMed
    Score: 0.034
  22. Identification of a novel putative pancreatic stem/progenitor cell marker DCAMKL-1 in normal mouse pancreas. Am J Physiol Gastrointest Liver Physiol. 2010 Aug; 299(2):G303-10.
    View in: PubMed
    Score: 0.033
  23. Doublecortin and CaM kinase-like-1 and leucine-rich-repeat-containing G-protein-coupled receptor mark quiescent and cycling intestinal stem cells, respectively. Stem Cells. 2009 Oct; 27(10):2571-9.
    View in: PubMed
    Score: 0.031
  24. Selective blockade of DCAMKL-1 results in tumor growth arrest by a Let-7a MicroRNA-dependent mechanism. Gastroenterology. 2009 Aug; 137(2):649-59, 659.e1-2.
    View in: PubMed
    Score: 0.030
  25. Loss of p21Waf1/Cip1/Sdi1 enhances intestinal stem cell survival following radiation injury. Am J Physiol Gastrointest Liver Physiol. 2009 Feb; 296(2):G245-54.
    View in: PubMed
    Score: 0.030
  26. Knockdown of RNA binding protein musashi-1 leads to tumor regression in vivo. Gastroenterology. 2008 May; 134(5):1448-58.
    View in: PubMed
    Score: 0.028
  27. Identification of a novel putative gastrointestinal stem cell and adenoma stem cell marker, doublecortin and CaM kinase-like-1, following radiation injury and in adenomatous polyposis coli/multiple intestinal neoplasia mice. Stem Cells. 2008 Mar; 26(3):630-7.
    View in: PubMed
    Score: 0.028
  28. Azoxymethane protects intestinal stem cells and reduces crypt epithelial mitosis through a COX-1-dependent mechanism. Am J Physiol Gastrointest Liver Physiol. 2006 Dec; 291(6):G1062-70.
    View in: PubMed
    Score: 0.025
  29. A zinc transporter drives glioblastoma progression via extracellular vesicles-reprogrammed microglial plasticity. Proc Natl Acad Sci U S A. 2025 May 06; 122(18):e2427073122.
    View in: PubMed
    Score: 0.023
  30. FGF-20: FGFs--they keep growing and growing and growing! Inflamm Bowel Dis. 2003 Mar; 9(2):133.
    View in: PubMed
    Score: 0.020
  31. Prosurvival and antiapoptotic effects of PGE2 in radiation injury are mediated by EP2 receptor in intestine. Am J Physiol Gastrointest Liver Physiol. 2003 Mar; 284(3):G490-8.
    View in: PubMed
    Score: 0.019
  32. Acetyl-Coenzyme A Synthetase 2 Potentiates Macropinocytosis and Muscle Wasting Through Metabolic Reprogramming in Pancreatic Cancer. Gastroenterology. 2022 11; 163(5):1281-1293.e1.
    View in: PubMed
    Score: 0.019
  33. Circular RNA ANAPC7 Inhibits Tumor Growth and Muscle Wasting via PHLPP2-AKT-TGF-ß Signaling Axis in Pancreatic Cancer. Gastroenterology. 2022 06; 162(7):2004-2017.e2.
    View in: PubMed
    Score: 0.018
  34. Clinical implications of prostaglandin inhibition in the small bowel. Gastroenterol Clin North Am. 2001 Dec; 30(4):953-69.
    View in: PubMed
    Score: 0.018
  35. Zinc-Dependent Regulation of ZEB1 and YAP1 Coactivation Promotes Epithelial-Mesenchymal Transition Plasticity and Metastasis in Pancreatic Cancer. Gastroenterology. 2021 04; 160(5):1771-1783.e1.
    View in: PubMed
    Score: 0.017
  36. Disruption of cyclooxygenase-1 gene results in an impaired response to radiation injury. Am J Physiol Gastrointest Liver Physiol. 2000 Nov; 279(5):G858-65.
    View in: PubMed
    Score: 0.017
  37. Proximal colon-derived O-glycosylated mucus encapsulates and modulates the microbiota. Science. 2020 10 23; 370(6515):467-472.
    View in: PubMed
    Score: 0.017
  38. ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin a3ß1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells. Gastroenterology. 2020 02; 158(3):679-692.e1.
    View in: PubMed
    Score: 0.016
  39. FGF-2 enhances intestinal stem cell survival and its expression is induced after radiation injury. Am J Physiol. 1999 01; 276(1):G249-58.
    View in: PubMed
    Score: 0.015
  40. Dclk1 in tuft cells promotes inflammation-driven epithelial restitution and mitigates chronic colitis. Cell Death Differ. 2019 09; 26(9):1656-1669.
    View in: PubMed
    Score: 0.015
  41. ZIP4 Promotes Muscle Wasting and Cachexia in Mice With Orthotopic Pancreatic Tumors by Stimulating RAB27B-Regulated Release of Extracellular Vesicles From Cancer Cells. Gastroenterology. 2019 02; 156(3):722-734.e6.
    View in: PubMed
    Score: 0.015
  42. ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism. Clin Cancer Res. 2018 07 01; 24(13):3186-3196.
    View in: PubMed
    Score: 0.014
  43. Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity. Cell Stem Cell. 2017 07 06; 21(1):78-90.e6.
    View in: PubMed
    Score: 0.013
  44. (Z)-3,5,4'-Trimethoxystilbene Limits Hepatitis C and Cancer Pathophysiology by Blocking Microtubule Dynamics and Cell-Cycle Progression. Cancer Res. 2016 08 15; 76(16):4887-96.
    View in: PubMed
    Score: 0.012
  45. Dclk1 Defines Quiescent Pancreatic Progenitors that Promote Injury-Induced Regeneration and Tumorigenesis. Cell Stem Cell. 2016 Apr 07; 18(4):441-55.
    View in: PubMed
    Score: 0.012
  46. Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice. Gastroenterology. 2016 07; 151(1):152-164.e11.
    View in: PubMed
    Score: 0.012
  47. ZIP4 silencing improves bone loss in pancreatic cancer. Oncotarget. 2015 Sep 22; 6(28):26041-51.
    View in: PubMed
    Score: 0.012
  48. Novel regenerative peptide TP508 mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity. Lab Invest. 2015 Nov; 95(11):1222-33.
    View in: PubMed
    Score: 0.012
  49. Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression. Oncotarget. 2015 Jun 20; 6(17):15524-39.
    View in: PubMed
    Score: 0.012
  50. Translational research on Barrett's esophagus. Ann N Y Acad Sci. 2014 Sep; 1325:170-86.
    View in: PubMed
    Score: 0.011
  51. Long-lived intestinal tuft cells serve as colon cancer-initiating cells. J Clin Invest. 2014 Mar; 124(3):1283-95.
    View in: PubMed
    Score: 0.011
  52. A multicenter study to standardize reporting and analyses of fluorescence-activated cell-sorted murine intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2013 Oct 15; 305(8):G542-51.
    View in: PubMed
    Score: 0.010
  53. Utility of a bacterial infection model to study epithelial-mesenchymal transition, mesenchymal-epithelial transition or tumorigenesis. Oncogene. 2014 May 15; 33(20):2639-54.
    View in: PubMed
    Score: 0.010
  54. Toll-like receptor-7 ligand Imiquimod induces type I interferon and antimicrobial peptides to ameliorate dextran sodium sulfate-induced acute colitis. Inflamm Bowel Dis. 2012 May; 18(5):955-67.
    View in: PubMed
    Score: 0.009
  55. RNA binding protein CUGBP2/CELF2 mediates curcumin-induced mitotic catastrophe of pancreatic cancer cells. PLoS One. 2011 Feb 11; 6(2):e16958.
    View in: PubMed
    Score: 0.009
  56. Curcumin and turmeric attenuate arsenic-induced angiogenesis in ovo. Altern Ther Health Med. 2010 Mar-Apr; 16(2):12-4.
    View in: PubMed
    Score: 0.008
  57. Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis. Gastroenterology. 2010 Feb; 138(2):616-26, 626.e1-2.
    View in: PubMed
    Score: 0.008
  58. Enterococcus faecalis induces aneuploidy and tetraploidy in colonic epithelial cells through a bystander effect. Cancer Res. 2008 Dec 01; 68(23):9909-17.
    View in: PubMed
    Score: 0.007
  59. Activation of apoptosis by 1-hydroxy-5,7-dimethoxy-2-naphthalene-carboxaldehyde, a novel compound from Aegle marmelos. Cancer Res. 2008 Oct 15; 68(20):8573-81.
    View in: PubMed
    Score: 0.007
  60. Dichotomous metabolism of Enterococcus faecalis induced by haematin starvation modulates colonic gene expression. J Med Microbiol. 2008 Oct; 57(Pt 10):1193-1204.
    View in: PubMed
    Score: 0.007
  61. Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastrophe. Oncogene. 2008 Jul 31; 27(33):4544-56.
    View in: PubMed
    Score: 0.007
  62. Diphenyl difluoroketone: a curcumin derivative with potent in vivo anticancer activity. Cancer Res. 2008 Mar 15; 68(6):1962-9.
    View in: PubMed
    Score: 0.007
  63. Novel intestinal splice variants of RNA-binding protein CUGBP2: isoform-specific effects on mitotic catastrophe. Am J Physiol Gastrointest Liver Physiol. 2008 Apr; 294(4):G971-81.
    View in: PubMed
    Score: 0.007
  64. Granulocyte macrophage colony-stimulating factor ameliorates DSS-induced experimental colitis. Inflamm Bowel Dis. 2008 Jan; 14(1):88-99.
    View in: PubMed
    Score: 0.007
  65. Epithelial apoptosis in mechanistically distinct methods of injury in the murine small intestine. Histol Histopathol. 2007 06; 22(6):623-30.
    View in: PubMed
    Score: 0.007
  66. Dysregulation of Reg gene expression occurs early in gastrointestinal tumorigenesis and regulates anti-apoptotic genes. Cancer Biol Ther. 2006 Dec; 5(12):1714-20.
    View in: PubMed
    Score: 0.006
  67. Functional antagonism between RNA binding proteins HuR and CUGBP2 determines the fate of COX-2 mRNA translation. Gastroenterology. 2007 Mar; 132(3):1055-65.
    View in: PubMed
    Score: 0.006
  68. PEGylated murine Granulocyte-macrophage colony-stimulating factor: production, purification, and characterization. Protein Expr Purif. 2005 Dec; 44(2):94-103.
    View in: PubMed
    Score: 0.006
  69. Apobec-1 protects intestine from radiation injury through posttranscriptional regulation of cyclooxygenase-2 expression. Gastroenterology. 2004 Oct; 127(4):1139-49.
    View in: PubMed
    Score: 0.006
  70. Dynamic antagonism between RNA-binding protein CUGBP2 and cyclooxygenase-2-mediated prostaglandin E2 in radiation damage. Proc Natl Acad Sci U S A. 2004 Sep 21; 101(38):13873-8.
    View in: PubMed
    Score: 0.006
  71. Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2. Mol Cell. 2003 Jan; 11(1):113-26.
    View in: PubMed
    Score: 0.005
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