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Courtney Houchen to Humans

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This is a "connection" page, showing publications Courtney Houchen has written about Humans.
Courtney Houchen
Connection Strength
1.212
Humans
  1. From Inflammation to Oncogenesis: Tracing Serum DCLK1 and miRNA Signatures in Chronic Liver Diseases. Int J Mol Sci. 2024 Jun 12; 25(12).
    View in: PubMed
    Score: 0.054
  2. Surging Liver Transplantation for Nonalcoholic Steatohepatitis from 2000-2022: A National Database Study. South Med J. 2024 Jun; 117(6):302-310.
    View in: PubMed
    Score: 0.053
  3. Epigenetic Landscape and Therapeutic Implication of Gene Isoforms of Doublecortin-Like Kinase 1 for Cancer Stem Cells. Int J Mol Sci. 2023 Nov 16; 24(22).
    View in: PubMed
    Score: 0.052
  4. A subset of epithelial cells mimics regulatory T cells and contributes to immune evasion during development of pancreatic adenocarcinoma. BMC Med. 2020 06 29; 18(1):155.
    View in: PubMed
    Score: 0.041
  5. Doublecortin-like kinase 1 promotes hepatocyte clonogenicity and oncogenic programming via non-canonical ß-catenin-dependent mechanism. Sci Rep. 2020 06 29; 10(1):10578.
    View in: PubMed
    Score: 0.041
  6. DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization. Mol Cancer Ther. 2020 07; 19(7):1539-1549.
    View in: PubMed
    Score: 0.040
  7. Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer. Int J Cancer. 2018 09 01; 143(5):1162-1175.
    View in: PubMed
    Score: 0.035
  8. Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells. Mol Cancer. 2017 02 01; 16(1):30.
    View in: PubMed
    Score: 0.032
  9. Survival of Patients with Gastrointestinal Cancers Can Be Predicted by a Surrogate microRNA Signature for Cancer Stem-like Cells Marked by DCLK1 Kinase. Cancer Res. 2016 07 15; 76(14):4090-9.
    View in: PubMed
    Score: 0.031
  10. Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism. Oncotarget. 2015 Nov 10; 6(35):37200-15.
    View in: PubMed
    Score: 0.030
  11. Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewal. Oncotarget. 2015 Oct 13; 6(31):30876-86.
    View in: PubMed
    Score: 0.029
  12. Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases. Oncotarget. 2015 Aug 21; 6(24):20327-44.
    View in: PubMed
    Score: 0.029
  13. Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells. PLoS One. 2015; 10(2):e0118933.
    View in: PubMed
    Score: 0.028
  14. DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma. Oncotarget. 2015 Feb 10; 6(4):2193-205.
    View in: PubMed
    Score: 0.028
  15. DCLK1 is detectable in plasma of patients with Barrett's esophagus and esophageal adenocarcinoma. Dig Dis Sci. 2015 Feb; 60(2):509-13.
    View in: PubMed
    Score: 0.027
  16. Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1. Mol Cancer. 2014 May 06; 13:103.
    View in: PubMed
    Score: 0.027
  17. Intestinal stem cells and the colorectal cancer microenvironment. World J Gastroenterol. 2014 Feb 28; 20(8):1898-909.
    View in: PubMed
    Score: 0.026
  18. Fluvastatin interferes with hepatitis C virus replication via microtubule bundling and a doublecortin-like kinase-mediated mechanism. PLoS One. 2013; 8(11):e80304.
    View in: PubMed
    Score: 0.026
  19. DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer. PLoS One. 2013; 8(9):e73940.
    View in: PubMed
    Score: 0.025
  20. Epigenetic variants and biomarkers for colon cancer. Am J Pathol. 2012 Jun; 180(6):2205-7.
    View in: PubMed
    Score: 0.023
  21. Identification of the putative intestinal stem cell marker doublecortin and CaM kinase-like-1 in Barrett's esophagus and esophageal adenocarcinoma. J Gastroenterol Hepatol. 2012 Apr; 27(4):773-80.
    View in: PubMed
    Score: 0.023
  22. Hepatitis C virus-induced cancer stem cell-like signatures in cell culture and murine tumor xenografts. J Virol. 2011 Dec; 85(23):12292-303.
    View in: PubMed
    Score: 0.022
  23. Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism. J Nanobiotechnology. 2011 Sep 19; 9:40.
    View in: PubMed
    Score: 0.022
  24. DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism. Cancer Res. 2011 Mar 15; 71(6):2328-38.
    View in: PubMed
    Score: 0.021
  25. Doublecortin and CaM kinase-like-1 and leucine-rich-repeat-containing G-protein-coupled receptor mark quiescent and cycling intestinal stem cells, respectively. Stem Cells. 2009 Oct; 27(10):2571-9.
    View in: PubMed
    Score: 0.019
  26. 14-3-3sigma-dependent resistance to cisplatin. Anticancer Res. 2009 Jun; 29(6):2009-14.
    View in: PubMed
    Score: 0.019
  27. Selective blockade of DCAMKL-1 results in tumor growth arrest by a Let-7a MicroRNA-dependent mechanism. Gastroenterology. 2009 Aug; 137(2):649-59, 659.e1-2.
    View in: PubMed
    Score: 0.019
  28. HuR and TTP: two RNA binding proteins that deliver message from the 3' end. Gastroenterology. 2009 May; 136(5):1495-8.
    View in: PubMed
    Score: 0.019
  29. Knockdown of RNA binding protein musashi-1 leads to tumor regression in vivo. Gastroenterology. 2008 May; 134(5):1448-58.
    View in: PubMed
    Score: 0.017
  30. EP4 mediates PGE2 dependent cell survival through the PI3 kinase/AKT pathway. Prostaglandins Other Lipid Mediat. 2007 Feb; 83(1-2):112-20.
    View in: PubMed
    Score: 0.016
  31. Lysosomes Promote Cancer Metastasis via Exosome in PTEN-Deficient Tumors. Gastroenterology. 2023 03; 164(3):329-331.
    View in: PubMed
    Score: 0.012
  32. Targeting Doublecortin-Like Kinase 1 (DCLK1)-Regulated SARS-CoV-2 Pathogenesis in COVID-19. J Virol. 2022 09 14; 96(17):e0096722.
    View in: PubMed
    Score: 0.012
  33. Patient-Derived Organoid Pharmacotyping Guides Precision Medicine for Pancreatic Cancer. Clin Cancer Res. 2022 08 02; 28(15):3176-3178.
    View in: PubMed
    Score: 0.012
  34. Acetyl-Coenzyme A Synthetase 2 Potentiates Macropinocytosis and Muscle Wasting Through Metabolic Reprogramming in Pancreatic Cancer. Gastroenterology. 2022 11; 163(5):1281-1293.e1.
    View in: PubMed
    Score: 0.012
  35. Reg4 Interacts with CD44 to Regulate Proliferation and Stemness of Colorectal and Pancreatic Cancer Cells. Mol Cancer Res. 2022 Mar 01; 20(3):387-399.
    View in: PubMed
    Score: 0.011
  36. Circular RNA ANAPC7 Inhibits Tumor Growth and Muscle Wasting via PHLPP2-AKT-TGF-ß Signaling Axis in Pancreatic Cancer. Gastroenterology. 2022 06; 162(7):2004-2017.e2.
    View in: PubMed
    Score: 0.011
  37. A Novel Translational Activation of HIF1a Promotes Pancreatic Cancer Growth Through Glycolytic Reprogramming. Gastroenterology. 2022 04; 162(4):1040-1042.
    View in: PubMed
    Score: 0.011
  38. Attenuating DNA damage response and immunosuppression radiosensitizes pancreatic cancer. EBioMedicine. 2022 Feb; 76:103822.
    View in: PubMed
    Score: 0.011
  39. Clinical implications of prostaglandin inhibition in the small bowel. Gastroenterol Clin North Am. 2001 Dec; 30(4):953-69.
    View in: PubMed
    Score: 0.011
  40. Interplay of Tumor Microenvironment Factors and Cancer Stem Cell Enrichment in Pancreatic Ductal Adenocarcinoma. Gastroenterology. 2021 12; 161(6):1800-1802.
    View in: PubMed
    Score: 0.011
  41. An integrated model of N6-methyladenosine regulators to predict tumor aggressiveness and immune evasion in pancreatic cancer. EBioMedicine. 2021 Mar; 65:103271.
    View in: PubMed
    Score: 0.011
  42. Zinc-Dependent Regulation of ZEB1 and YAP1 Coactivation Promotes Epithelial-Mesenchymal Transition Plasticity and Metastasis in Pancreatic Cancer. Gastroenterology. 2021 04; 160(5):1771-1783.e1.
    View in: PubMed
    Score: 0.011
  43. ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin a3ß1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells. Gastroenterology. 2020 02; 158(3):679-692.e1.
    View in: PubMed
    Score: 0.010
  44. FGF-2 enhances intestinal stem cell survival and its expression is induced after radiation injury. Am J Physiol. 1999 01; 276(1):G249-58.
    View in: PubMed
    Score: 0.009
  45. Dclk1 in tuft cells promotes inflammation-driven epithelial restitution and mitigates chronic colitis. Cell Death Differ. 2019 09; 26(9):1656-1669.
    View in: PubMed
    Score: 0.009
  46. ZIP4 Promotes Muscle Wasting and Cachexia in Mice With Orthotopic Pancreatic Tumors by Stimulating RAB27B-Regulated Release of Extracellular Vesicles From Cancer Cells. Gastroenterology. 2019 02; 156(3):722-734.e6.
    View in: PubMed
    Score: 0.009
  47. ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism. Clin Cancer Res. 2018 07 01; 24(13):3186-3196.
    View in: PubMed
    Score: 0.009
  48. APSA Awardee Submission: Tumor/cancer stem cell marker doublecortin-like kinase 1 in liver diseases. Exp Biol Med (Maywood). 2017 02; 242(3):242-249.
    View in: PubMed
    Score: 0.008
  49. (Z)-3,5,4'-Trimethoxystilbene Limits Hepatitis C and Cancer Pathophysiology by Blocking Microtubule Dynamics and Cell-Cycle Progression. Cancer Res. 2016 08 15; 76(16):4887-96.
    View in: PubMed
    Score: 0.008
  50. Serum CA125 is a novel predictive marker for pancreatic cancer metastasis and correlates with the metastasis-associated burden. Oncotarget. 2016 Feb 02; 7(5):5943-56.
    View in: PubMed
    Score: 0.008
  51. ZIP4 silencing improves bone loss in pancreatic cancer. Oncotarget. 2015 Sep 22; 6(28):26041-51.
    View in: PubMed
    Score: 0.007
  52. An Ethanol Extract of Hawaiian Turmeric: Extensive In Vitro Anticancer Activity Against Human Colon Cancer Cells. Altern Ther Health Med. 2015; 21 Suppl 2:46-54.
    View in: PubMed
    Score: 0.007
  53. Translational research on Barrett's esophagus. Ann N Y Acad Sci. 2014 Sep; 1325:170-86.
    View in: PubMed
    Score: 0.007
  54. Wnt inhibitory factor 1 suppresses cancer stemness and induces cellular senescence. Cell Death Dis. 2014 May 22; 5:e1246.
    View in: PubMed
    Score: 0.007
  55. Reg4-induced mitogenesis involves Akt-GSK3ß-ß-Catenin-TCF-4 signaling in human colorectal cancer. Mol Carcinog. 2014 Feb; 53 Suppl 1:E169-80.
    View in: PubMed
    Score: 0.006
  56. A nomenclature for intestinal in vitro cultures. Am J Physiol Gastrointest Liver Physiol. 2012 Jun 15; 302(12):G1359-63.
    View in: PubMed
    Score: 0.006
  57. Toll-like receptor-7 ligand Imiquimod induces type I interferon and antimicrobial peptides to ameliorate dextran sodium sulfate-induced acute colitis. Inflamm Bowel Dis. 2012 May; 18(5):955-67.
    View in: PubMed
    Score: 0.006
  58. RNA binding protein CUGBP2/CELF2 mediates curcumin-induced mitotic catastrophe of pancreatic cancer cells. PLoS One. 2011 Feb 11; 6(2):e16958.
    View in: PubMed
    Score: 0.005
  59. Urine and serum analysis of consumed curcuminoids using an IkappaB-luciferase surrogate marker assay. In Vivo. 2010 Nov-Dec; 24(6):861-4.
    View in: PubMed
    Score: 0.005
  60. Cancer stem cells: a novel paradigm for cancer prevention and treatment. Mini Rev Med Chem. 2010 May; 10(5):359-71.
    View in: PubMed
    Score: 0.005
  61. Curcumin and turmeric attenuate arsenic-induced angiogenesis in ovo. Altern Ther Health Med. 2010 Mar-Apr; 16(2):12-4.
    View in: PubMed
    Score: 0.005
  62. Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis. Gastroenterology. 2010 Feb; 138(2):616-26, 626.e1-2.
    View in: PubMed
    Score: 0.005
  63. Enterococcus faecalis induces aneuploidy and tetraploidy in colonic epithelial cells through a bystander effect. Cancer Res. 2008 Dec 01; 68(23):9909-17.
    View in: PubMed
    Score: 0.005
  64. Activation of apoptosis by 1-hydroxy-5,7-dimethoxy-2-naphthalene-carboxaldehyde, a novel compound from Aegle marmelos. Cancer Res. 2008 Oct 15; 68(20):8573-81.
    View in: PubMed
    Score: 0.005
  65. Dichotomous metabolism of Enterococcus faecalis induced by haematin starvation modulates colonic gene expression. J Med Microbiol. 2008 Oct; 57(Pt 10):1193-1204.
    View in: PubMed
    Score: 0.005
  66. Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastrophe. Oncogene. 2008 Jul 31; 27(33):4544-56.
    View in: PubMed
    Score: 0.004
  67. Diphenyl difluoroketone: a curcumin derivative with potent in vivo anticancer activity. Cancer Res. 2008 Mar 15; 68(6):1962-9.
    View in: PubMed
    Score: 0.004
  68. CUGBP2 downregulation by prostaglandin E2 protects colon cancer cells from radiation-induced mitotic catastrophe. Am J Physiol Gastrointest Liver Physiol. 2008 May; 294(5):G1235-44.
    View in: PubMed
    Score: 0.004
  69. Translation inhibition during cell cycle arrest and apoptosis: Mcl-1 is a novel target for RNA binding protein CUGBP2. Am J Physiol Gastrointest Liver Physiol. 2008 Apr; 294(4):G1025-32.
    View in: PubMed
    Score: 0.004
  70. Novel intestinal splice variants of RNA-binding protein CUGBP2: isoform-specific effects on mitotic catastrophe. Am J Physiol Gastrointest Liver Physiol. 2008 Apr; 294(4):G971-81.
    View in: PubMed
    Score: 0.004
  71. Gastrin-mediated interleukin-8 and cyclooxygenase-2 gene expression: differential transcriptional and posttranscriptional mechanisms. Gastroenterology. 2008 Apr; 134(4):1070-82.
    View in: PubMed
    Score: 0.004
  72. Dysregulation of Reg gene expression occurs early in gastrointestinal tumorigenesis and regulates anti-apoptotic genes. Cancer Biol Ther. 2006 Dec; 5(12):1714-20.
    View in: PubMed
    Score: 0.004
  73. Functional antagonism between RNA binding proteins HuR and CUGBP2 determines the fate of COX-2 mRNA translation. Gastroenterology. 2007 Mar; 132(3):1055-65.
    View in: PubMed
    Score: 0.004
  74. Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas. Gastroenterology. 2006 Jan; 130(1):137-49.
    View in: PubMed
    Score: 0.004
  75. CUGBP2 plays a critical role in apoptosis of breast cancer cells in response to genotoxic injury. Ann N Y Acad Sci. 2003 Dec; 1010:504-9.
    View in: PubMed
    Score: 0.003
  76. Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2. Mol Cell. 2003 Jan; 11(1):113-26.
    View in: PubMed
    Score: 0.003
  77. Expression of the regenerating gene family in inflammatory bowel disease mucosa: Reg Ialpha upregulation, processing, and antiapoptotic activity. J Investig Med. 2002 Nov; 50(6):421-34.
    View in: PubMed
    Score: 0.003
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The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.