Kevin Brown to Skin Neoplasms
This is a "connection" page, showing publications Kevin Brown has written about Skin Neoplasms.
Connection Strength
5.484
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A UVB-responsive common variant at chromosome band 7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor, AHR. Am J Hum Genet. 2021 09 02; 108(9):1611-1630.
Score: 0.679
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Cell-type-specific meQTLs extend melanoma GWAS annotation beyond eQTLs and inform melanocyte gene-regulatory mechanisms. Am J Hum Genet. 2021 09 02; 108(9):1631-1646.
Score: 0.677
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Novel MAPK/AKT-impairing germline NRAS variant identified in a melanoma-prone family. Fam Cancer. 2022 07; 21(3):347-355.
Score: 0.675
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A cryptic BAP1 splice mutation in a family with uveal and cutaneous melanoma, and paraganglioma. Pigment Cell Melanoma Res. 2012 Nov; 25(6):815-8.
Score: 0.368
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Common sequence variants on 20q11.22 confer melanoma susceptibility. Nat Genet. 2008 Jul; 40(7):838-40.
Score: 0.272
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Massively parallel reporter assays and variant scoring identified functional variants and target genes for melanoma loci and highlighted cell-type specificity. Am J Hum Genet. 2022 Dec 01; 109(12):2210-2229.
Score: 0.186
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Defining novel causal SNPs and linked phenotypes at melanoma-associated loci. Hum Mol Genet. 2022 08 25; 31(17):2845-2856.
Score: 0.183
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Functional annotation and investigation of the 10q24.33 melanoma risk locus identifies a common variant that influences transcriptional regulation of OBFC1. Hum Mol Genet. 2022 03 21; 31(6):863-874.
Score: 0.177
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Integrated Analysis of Coexpression and Exome Sequencing to Prioritize Susceptibility Genes for Familial Cutaneous Melanoma. J Invest Dermatol. 2022 09; 142(9):2464-2475.e5.
Score: 0.176
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Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility. Nat Genet. 2020 05; 52(5):494-504.
Score: 0.155
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Analysis of DNA methylation patterns in the tumor immune microenvironment of metastatic melanoma. Mol Oncol. 2020 05; 14(5):933-950.
Score: 0.154
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Overlapping genetic architecture between Parkinson disease and melanoma. Acta Neuropathol. 2020 02; 139(2):347-364.
Score: 0.152
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Evaluation of the contribution of germline variants in BRCA1 and BRCA2 to uveal and cutaneous melanoma. Melanoma Res. 2019 10; 29(5):483-490.
Score: 0.149
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Combining common genetic variants and non-genetic risk factors to predict risk of cutaneous melanoma. Hum Mol Genet. 2018 12 01; 27(23):4145-4156.
Score: 0.141
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Assessing the Incremental Contribution of Common Genomic Variants to Melanoma Risk Prediction in Two Population-Based Studies. J Invest Dermatol. 2018 12; 138(12):2617-2624.
Score: 0.136
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Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148. Nat Commun. 2017 05 02; 8:15034.
Score: 0.126
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A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis. Cell Rep. 2016 05 31; 15(9):1884-92.
Score: 0.118
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Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma. Nat Genet. 2015 Sep; 47(9):987-995.
Score: 0.112
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Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma. J Natl Cancer Inst. 2015 Feb; 107(2).
Score: 0.107
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The effect on melanoma risk of genes previously associated with telomere length. J Natl Cancer Inst. 2014 Oct; 106(10).
Score: 0.105
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Identification of a melanoma susceptibility locus and somatic mutation in TET2. Carcinogenesis. 2014 Sep; 35(9):2097-101.
Score: 0.104
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Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing. Nat Genet. 2011 Dec 25; 44(2):165-9.
Score: 0.087
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Meta-analysis combining new and existing data sets confirms that the TERT-CLPTM1L locus influences melanoma risk. J Invest Dermatol. 2012 Feb; 132(2):485-7.
Score: 0.086
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Genome-wide association study identifies three new melanoma susceptibility loci. Nat Genet. 2011 Oct 09; 43(11):1108-13.
Score: 0.086
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Genome-wide association study identifies novel loci predisposing to cutaneous melanoma. Hum Mol Genet. 2011 Dec 15; 20(24):5012-23.
Score: 0.086
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Epigenetic transdifferentiation of normal melanocytes by a metastatic melanoma microenvironment. Cancer Res. 2005 Nov 15; 65(22):10164-9.
Score: 0.057
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The genomic landscape of cutaneous melanoma. Pigment Cell Melanoma Res. 2016 May; 29(3):266-83.
Score: 0.029
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Germline TERT promoter mutations are rare in familial melanoma. Fam Cancer. 2016 Jan; 15(1):139-44.
Score: 0.029
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Assessment of PALB2 as a candidate melanoma susceptibility gene. PLoS One. 2014; 9(6):e100683.
Score: 0.026
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POT1 loss-of-function variants predispose to familial melanoma. Nat Genet. 2014 May; 46(5):478-481.
Score: 0.025
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A versatile gene-based test for genome-wide association studies. Am J Hum Genet. 2010 Jul 09; 87(1):139-45.
Score: 0.020