Lawrence Rothblum to Transcription, Genetic
This is a "connection" page, showing publications Lawrence Rothblum has written about Transcription, Genetic.
Connection Strength
4.132
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Selective inhibition of rDNA transcription by a small-molecule peptide that targets the interface between RNA polymerase I and Rrn3. Mol Cancer Res. 2014 Nov; 12(11):1586-96.
Score: 0.413
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DNA binding by the ribosomal DNA transcription factor rrn3 is essential for ribosomal DNA transcription. J Biol Chem. 2013 Mar 29; 288(13):9135-44.
Score: 0.374
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Rrn3 becomes inactivated in the process of ribosomal DNA transcription. J Biol Chem. 2003 May 23; 278(21):18953-9.
Score: 0.188
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The Mammalian and Yeast A49 and A34 Heterodimers: Homologous but Not the Same. Genes (Basel). 2021 04 22; 12(5).
Score: 0.165
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Dynamics of the RNA polymerase I TFIIF/TFIIE-like subcomplex: a mini-review. Biochem Soc Trans. 2020 10 30; 48(5):1917-1927.
Score: 0.160
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Rb and p130 regulate RNA polymerase I transcription: Rb disrupts the interaction between UBF and SL-1. Oncogene. 2000 Oct 12; 19(43):4988-99.
Score: 0.159
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RNA polymerase I transcription in confluent cells: Rb downregulates rDNA transcription during confluence-induced cell cycle arrest. Oncogene. 2000 Jul 20; 19(31):3487-97.
Score: 0.157
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Conditional depletion of the RNA polymerase I subunit PAF53 reveals that it is essential for mitosis and enables identification of functional domains. J Biol Chem. 2019 12 27; 294(52):19907-19922.
Score: 0.149
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Transcription by RNA polymerase I. Front Biosci. 1998 Mar 26; 3:d376-98.
Score: 0.133
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Cell cycle and growth stimuli regulate different steps of RNA polymerase I transcription. Gene. 2017 May 15; 612:36-48.
Score: 0.122
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Regulation of rDNA transcription during endothelin-1-induced hypertrophy of neonatal cardiomyocytes. Hyperphosphorylation of upstream binding factor, an rDNA transcription factor. Circ Res. 1996 Mar; 78(3):354-61.
Score: 0.116
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Regulation of ribosomal DNA transcription during contraction-induced hypertrophy of neonatal cardiomyocytes. J Biol Chem. 1996 Feb 09; 271(6):3213-20.
Score: 0.115
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Regulation of ribosomal DNA transcription during neonatal cardiomyocyte hypertrophy. Cardiovasc Res. 1995 Oct; 30(4):501-10.
Score: 0.112
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A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes. Genome Res. 2015 Feb; 25(2):201-12.
Score: 0.106
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Transcription from the rat 45S ribosomal DNA promoter does not require the factor UBF. Gene Expr. 1993; 3(3):229-36.
Score: 0.093
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Dysregulation of RNA polymerase I transcription during disease. Biochim Biophys Acta. 2013 Mar-Apr; 1829(3-4):342-60.
Score: 0.092
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Domains of the rat rDNA promoter must be aligned stereospecifically. Mol Cell Biol. 1992 Mar; 12(3):1266-75.
Score: 0.088
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Complementary in vivo and in vitro analyses of the interactions between the cis-acting elements of the rat rDNA promoter. Mol Cell Biochem. 1991 May 29-Jun 12; 104(1-2):127-35.
Score: 0.083
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Characterization of factors that direct transcription of rat ribosomal DNA. Mol Cell Biol. 1990 Jun; 10(6):3105-16.
Score: 0.078
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Interaction of RNA polymerase I transcription factors with a promoter in the nontranscribed spacer of rat ribosomal DNA. Nucleic Acids Res. 1990 Apr 11; 18(7):1677-85.
Score: 0.077
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Purification and characterization of a high-mobility-group-like DNA-binding protein that stimulates rRNA synthesis in vitro. Mol Cell Biol. 1988 Aug; 8(8):3406-14.
Score: 0.068
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Mammalian Rrn3 is required for the formation of a transcription competent preinitiation complex containing RNA polymerase I. Gene Expr. 2008; 14(3):131-47.
Score: 0.066
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Regions upstream from the core promoter of the rat ribosomal gene are required for the formation of a stable transcription initiation complex by RNA polymerase I in vitro. Biochim Biophys Acta. 1987 Jul 14; 909(2):133-44.
Score: 0.064
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Isolation, fractionation and reconstitution of a nuclear extract capable of transcribing ribosomal DNA. Mol Cell Biochem. 1987 Jan; 73(1):11-20.
Score: 0.061
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Transcriptional role for the nontranscribed spacer of rat ribosomal DNA. Mol Cell Biol. 1986 Aug; 6(8):2766-73.
Score: 0.059
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Characterization of rat ribosomal DNA. The highly repetitive sequences that flank the ribosomal RNA transcription unit are homologous and contain RNA polymerase III transcription initiation sites. J Mol Biol. 1984 Mar 25; 174(1):141-62.
Score: 0.051
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Transcription initiation site of rat ribosomal DNA. Nucleic Acids Res. 1982 Nov 25; 10(22):7345-62.
Score: 0.046
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A kinetic framework for a mammalian RNA polymerase in vivo. Science. 2002 Nov 22; 298(5598):1623-6.
Score: 0.046
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Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis. J Biol Chem. 2002 Jul 26; 277(30):27423-32.
Score: 0.044
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An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF. Mol Cell. 2001 Nov; 8(5):1063-73.
Score: 0.043
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The role of acetylation in rDNA transcription. Nucleic Acids Res. 2001 Oct 15; 29(20):4114-24.
Score: 0.043
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Competitive recruitment of CBP and Rb-HDAC regulates UBF acetylation and ribosomal transcription. Mol Cell. 2000 Nov; 6(5):1059-66.
Score: 0.040
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Ultrastructural analysis of nucleolar transcription in cells microinjected with 5-bromo-UTP. Histochem Cell Biol. 2000 Mar; 113(3):181-7.
Score: 0.038
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Identification of a mammalian RNA polymerase I holoenzyme containing components of the DNA repair/replication system. Nucleic Acids Res. 1999 Sep 15; 27(18):3720-7.
Score: 0.037
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Regulation of ribosomal DNA transcription by insulin. Am J Physiol. 1998 07; 275(1):C130-8.
Score: 0.034
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The nucleolus, a model for analysis of chromatin controls. Cold Spring Harb Symp Quant Biol. 1978; 42 Pt 2:665-83.
Score: 0.033
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Overexpression of the transcription factor UBF1 is sufficient to increase ribosomal DNA transcription in neonatal cardiomyocytes: implications for cardiac hypertrophy. Proc Natl Acad Sci U S A. 1996 Aug 06; 93(16):8750-5.
Score: 0.030
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Regulation of rDNA transcription factors during cardiomyocyte hypertrophy induced by adrenergic agents. J Biol Chem. 1995 Apr 07; 270(14):8290-7.
Score: 0.027
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Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product. Nature. 1995 Mar 09; 374(6518):177-80.
Score: 0.027
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The RNA polymerase I transcription factor UBF is the product of a primary response gene. J Biol Chem. 1995 Mar 03; 270(9):4209-12.
Score: 0.027
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Nucleologenesis: U3 snRNA-containing prenucleolar bodies move to sites of active pre-rRNA transcription after mitosis. Mol Biol Cell. 1994 Sep; 5(9):955-66.
Score: 0.026
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Coordinated decreases in rRNA gene transcription factors and rRNA synthesis during muscle cell differentiation. Proc Natl Acad Sci U S A. 1993 Sep 01; 90(17):7933-6.
Score: 0.024
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Dexamethasone stimulates rRNA gene transcription in rat myoblasts. Mol Cell Endocrinol. 1993 Aug; 94(2):243-52.
Score: 0.024
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Differential phosphorylation and localization of the transcription factor UBF in vivo in response to serum deprivation. In vitro dephosphorylation of UBF reduces its transactivation properties. J Biol Chem. 1992 Jan 05; 267(1):35-8.
Score: 0.022
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Phosphorylation of eukaryotic translation initiation factor 2alpha coordinates rRNA transcription and translation inhibition during endoplasmic reticulum stress. Mol Cell Biol. 2009 Aug; 29(15):4295-307.
Score: 0.018
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UBF levels determine the number of active ribosomal RNA genes in mammals. J Cell Biol. 2008 Dec 29; 183(7):1259-74.
Score: 0.018
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Additional RNA polymerase I initiation site within the nontranscribed spacer region of the rat rRNA gene. Mol Cell Biol. 1987 Jul; 7(7):2388-96.
Score: 0.016
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Ribosomal chromatin organization. Biochem Cell Biol. 2006 Aug; 84(4):444-9.
Score: 0.015
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Characterization of rat ribosomal DNA II. identification of the highly repetitive DNA in the 3' non-transcribed spacer. J Mol Biol. 1985 Aug 05; 184(3):389-98.
Score: 0.014
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A purified fraction containing RNA polymerase I that can accurately transcribe rat ribosomal RNA gene. Proc Natl Acad Sci U S A. 1984 Nov; 81(21):6672-5.
Score: 0.013
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mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF. Mol Cell Biol. 2003 Dec; 23(23):8862-77.
Score: 0.012
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Cardiac hypertrophy in vivo is associated with increased expression of the ribosomal gene transcription factor UBF. FEBS Lett. 2003 Jul 31; 548(1-3):79-84.
Score: 0.012
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The nucleotide sequence of the 5' region of rat 18S rDNA and adjoining spacer. Biochem Biophys Res Commun. 1982 Aug 31; 107(4):1571-6.
Score: 0.011
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Nucleotide sequence of the region between the 18S rRNA sequence and the 28S rRNA sequence of rat ribosomal DNA. Nucleic Acids Res. 1982 Jun 25; 10(12):3667-80.
Score: 0.011
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Revealing the unseen: the organizer region of the nucleolus. J Cell Sci. 2001 Sep; 114(Pt 17):3199-205.
Score: 0.011
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Cellular regulation of ribosomal DNA transcription:both rat and Xenopus UBF1 stimulate rDNA transcription in 3T3 fibroblasts. Nucleic Acids Res. 1999 Feb 15; 27(4):1205-13.
Score: 0.009
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Controls of nucleolar function in cancer cells. Adv Exp Med Biol. 1977 May 22-24; 92:125-80.
Score: 0.008
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Angiotensin II-induced hypertrophy of rat vascular smooth muscle is associated with increased 18 S rRNA synthesis and phosphorylation of the rRNA transcription factor, upstream binding factor. J Biol Chem. 1995 Oct 20; 270(42):25096-101.
Score: 0.007