Lijun Xia to Animals
This is a "connection" page, showing publications Lijun Xia has written about Animals.
Connection Strength
1.242
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Endothelial VWF is critical for the pathogenesis of vaso-occlusive episode in a mouse model of sickle cell disease. Proc Natl Acad Sci U S A. 2022 08 23; 119(34):e2207592119.
Score: 0.078
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Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin. Blood. 2021 05 20; 137(20):2756-2769.
Score: 0.072
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Proximal colon-derived O-glycosylated mucus encapsulates and modulates the microbiota. Science. 2020 10 23; 370(6515):467-472.
Score: 0.069
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Loss of mucin-type O-glycans impairs the integrity of the glomerular filtration barrier in the mouse kidney. J Biol Chem. 2017 10 06; 292(40):16491-16497.
Score: 0.055
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Loss of intestinal O-glycans promotes spontaneous duodenal tumors. Am J Physiol Gastrointest Liver Physiol. 2016 07 01; 311(1):G74-83.
Score: 0.051
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Core 1- and 3-derived O-glycans collectively maintain the colonic mucus barrier and protect against spontaneous colitis in mice. Mucosal Immunol. 2017 01; 10(1):91-103.
Score: 0.050
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Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice. Gastroenterology. 2016 07; 151(1):152-164.e11.
Score: 0.050
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CLEC-2 and podoplanin, partners again. Blood. 2016 Mar 31; 127(13):1629-30.
Score: 0.050
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Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice. J Biol Chem. 2015 Aug 14; 290(33):20159-66.
Score: 0.048
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Podoplanin requires sialylated O-glycans for stable expression on lymphatic endothelial cells and for interaction with platelets. Blood. 2014 Dec 04; 124(24):3656-65.
Score: 0.045
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Mucin-type O-glycosylation is critical for vascular integrity. Glycobiology. 2014 Dec; 24(12):1237-41.
Score: 0.044
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Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma. Cancer Res. 2013 Dec 15; 73(24):7254-64.
Score: 0.042
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Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2. Nature. 2013 Oct 03; 502(7469):105-9.
Score: 0.042
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Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice. J Clin Invest. 2011 Apr; 121(4):1657-66.
Score: 0.035
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Core 1-derived O-glycans are essential E-selectin ligands on neutrophils. Proc Natl Acad Sci U S A. 2010 May 18; 107(20):9204-9.
Score: 0.033
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Core 3-derived O-glycans are essential for intestinal mucus barrier function. Methods Enzymol. 2010; 479:123-41.
Score: 0.033
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Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice. J Clin Invest. 2008 Nov; 118(11):3725-37.
Score: 0.030
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P-selectin glycoprotein ligand-1 is highly expressed on Ly-6Chi monocytes and a major determinant for Ly-6Chi monocyte recruitment to sites of atherosclerosis in mice. Circulation. 2008 Jun 24; 117(25):3227-37.
Score: 0.029
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Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans. J Exp Med. 2007 Jun 11; 204(6):1417-29.
Score: 0.027
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Targeted disruption of the gene encoding core 1 beta1-3-galactosyltransferase (T-synthase) causes embryonic lethality and defective angiogenesis in mice. Methods Enzymol. 2006; 416:314-31.
Score: 0.025
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Surface fucosylation of human cord blood cells augments binding to P-selectin and E-selectin and enhances engraftment in bone marrow. Blood. 2004 Nov 15; 104(10):3091-6.
Score: 0.022
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Deletion of Talin1 in Myeloid Cells Facilitates Atherosclerosis in Mice. Arterioscler Thromb Vasc Biol. 2024 Aug; 44(8):1799-1812.
Score: 0.022
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Defective angiogenesis and fatal embryonic hemorrhage in mice lacking core 1-derived O-glycans. J Cell Biol. 2004 Feb 02; 164(3):451-9.
Score: 0.022
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PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves. Circ Res. 2023 09; 133(6):463-480.
Score: 0.021
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N-terminal residues in murine P-selectin glycoprotein ligand-1 required for binding to murine P-selectin. Blood. 2003 Jan 15; 101(2):552-9.
Score: 0.020
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P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flow. J Clin Invest. 2002 Apr; 109(7):939-50.
Score: 0.019
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Platelet TGF-ß1 deficiency decreases liver fibrosis in a mouse model of liver injury. Blood Adv. 2018 03 13; 2(5):470-480.
Score: 0.014
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A proteasome inhibitor, an antioxidant, or a salicylate, but not a glucocorticoid, blocks constitutive and cytokine-inducible expression of P-selectin in human endothelial cells. Blood. 1998 Mar 01; 91(5):1625-32.
Score: 0.014
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L-selectin mechanochemistry restricts neutrophil priming in vivo. Nat Commun. 2017 05 12; 8:15196.
Score: 0.014
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Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells. Mol Cancer. 2017 02 01; 16(1):30.
Score: 0.013
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Mechanotransduction activates canonical Wnt/ß-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves. Genes Dev. 2016 06 15; 30(12):1454-69.
Score: 0.013
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Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016 Jan 01; 409(1):218-233.
Score: 0.012
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O-glycans direct selectin ligands to lipid rafts on leukocytes. Proc Natl Acad Sci U S A. 2015 Jul 14; 112(28):8661-6.
Score: 0.012
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Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development. Nat Commun. 2015 Mar 16; 6:6380.
Score: 0.012
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Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function. Sci Signal. 2014 Oct 14; 7(347):ra97.
Score: 0.011
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Molecular and cellular mechanisms of lymphatic vascular maturation. Microvasc Res. 2014 Nov; 96:16-22.
Score: 0.011
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Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency. Arterioscler Thromb Vasc Biol. 2014 Feb; 34(2):331-337.
Score: 0.011
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Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling. J Clin Invest. 2012 Dec; 122(12):4424-38.
Score: 0.010
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Activation of AMP-activated protein kinase a2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo. Nat Med. 2012 Jun; 18(6):902-10.
Score: 0.010
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Carcinoma mucins trigger reciprocal activation of platelets and neutrophils in a murine model of Trousseau syndrome. Blood. 2011 Oct 13; 118(15):4015-23.
Score: 0.009
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Cytoplasmic domain of P-selectin glycoprotein ligand-1 facilitates dimerization and export from the endoplasmic reticulum. J Biol Chem. 2011 Mar 18; 286(11):9577-86.
Score: 0.009
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Differential regulation of human and murine P-selectin expression and function in vivo. J Exp Med. 2010 Dec 20; 207(13):2975-87.
Score: 0.009
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Separable requirements for cytoplasmic domain of PSGL-1 in leukocyte rolling and signaling under flow. Blood. 2008 Sep 01; 112(5):2035-45.
Score: 0.007
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Bone marrow dysfunction in mice lacking the cytokine receptor gp130 in endothelial cells. Blood. 2005 Dec 15; 106(13):4093-101.
Score: 0.006
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Divergent inducible expression of P-selectin and E-selectin in mice and primates. Blood. 1999 Dec 01; 94(11):3820-8.
Score: 0.004
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Comparison of promoters for the murine and human P-selectin genes suggests species-specific and conserved mechanisms for transcriptional regulation in endothelial cells. J Biol Chem. 1998 Apr 17; 273(16):10058-67.
Score: 0.004
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Tumor necrosis factor-alpha- or lipopolysaccharide-induced expression of the murine P-selectin gene in endothelial cells involves novel kappaB sites and a variant activating transcription factor/cAMP response element. J Biol Chem. 1998 Apr 17; 273(16):10068-77.
Score: 0.004