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Connection

Doris Benbrook to Animals

This is a "connection" page, showing publications Doris Benbrook has written about Animals.
Connection Strength

0.873
  1. Targeting HSP70-E7 Interaction With SHetA2: A Novel Therapeutic Strategy for Cervical Cancer. J Med Virol. 2024 Nov; 96(11):e70088.
    View in: PubMed
    Score: 0.092
  2. Similarities and Differences of Hsp70, hsc70, Grp78 and Mortalin as Cancer Biomarkers and Drug Targets. Cells. 2021 11 03; 10(11).
    View in: PubMed
    Score: 0.075
  3. Novel ovarian cancer maintenance therapy targeted at mortalin and mutant p53. Int J Cancer. 2020 08 15; 147(4):1086-1097.
    View in: PubMed
    Score: 0.066
  4. Development of a dietary formulation of the SHetA2 chemoprevention drug for mice. Invest New Drugs. 2018 08; 36(4):561-570.
    View in: PubMed
    Score: 0.057
  5. History of retinoic acid receptors. Subcell Biochem. 2014; 70:1-20.
    View in: PubMed
    Score: 0.043
  6. Chemoprevention of colon and small intestinal tumorigenesis in APC(min/+) mice by SHetA2 (NSC721689) without toxicity. Cancer Prev Res (Phila). 2013 Sep; 6(9):908-16.
    View in: PubMed
    Score: 0.042
  7. The pro-survival function of Akt kinase can be overridden or altered to contribute to induction of apoptosis. Curr Cancer Drug Targets. 2011 Jun; 11(5):586-99.
    View in: PubMed
    Score: 0.036
  8. Development of flexible-heteroarotinoids for kidney cancer. Mol Cancer Ther. 2009 May; 8(5):1227-38.
    View in: PubMed
    Score: 0.031
  9. Flexible heteroarotinoid (Flex-Het) SHetA2 inhibits angiogenesis in vitro and in vivo. Invest New Drugs. 2009 Aug; 27(4):304-18.
    View in: PubMed
    Score: 0.030
  10. Flexible heteroarotinoids (Flex-Hets) exhibit improved therapeutic ratios as anti-cancer agents over retinoic acid receptor agonists. Invest New Drugs. 2005 Oct; 23(5):417-28.
    View in: PubMed
    Score: 0.024
  11. Pharmacodynamics of Cyclin D1 Degradation in Ovarian Cancer Xenografts with Repeated Oral SHetA2 Dosing. AAPS J. 2023 Dec 12; 26(1):5.
    View in: PubMed
    Score: 0.022
  12. Niclosamide causes lysosome-dependent cell death in endometrial cancer cells and tumors. Biomed Pharmacother. 2023 May; 161:114422.
    View in: PubMed
    Score: 0.020
  13. Refining retinoids with heteroatoms. Mini Rev Med Chem. 2002 Jun; 2(3):277-83.
    View in: PubMed
    Score: 0.019
  14. An ELISA method for detection of human antibodies to an immunotoxin. J Pharmacol Toxicol Methods. 2002 May-Jun; 47(3):169-75.
    View in: PubMed
    Score: 0.019
  15. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382.
    View in: PubMed
    Score: 0.018
  16. Potential and mechanism of mebendazole for treatment and maintenance of ovarian cancer. Gynecol Oncol. 2021 01; 160(1):302-311.
    View in: PubMed
    Score: 0.017
  17. Vaginal Suppositories Containing SHetA2 to Treat Cervical Dysplasia: Pharmacokinetics of Daily Doses and Preliminary Safety Profile. J Pharm Sci. 2020 06; 109(6):2000-2008.
    View in: PubMed
    Score: 0.017
  18. Physiologically Based Pharmacokinetic Modeling and Tissue Distribution Characteristics of SHetA2 in Tumor-Bearing Mice. AAPS J. 2020 02 21; 22(2):51.
    View in: PubMed
    Score: 0.017
  19. Heteroarotinoids inhibit head and neck cancer cell lines in vitro and in vivo through both RAR and RXR retinoic acid receptors. J Med Chem. 1999 Oct 21; 42(21):4434-45.
    View in: PubMed
    Score: 0.016
  20. Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research. Geroscience. 2019 04; 41(2):209-227.
    View in: PubMed
    Score: 0.016
  21. Synthesis and characterization of heteroarotinoids demonstrate structure specificity relationships. J Med Chem. 1998 Sep 10; 41(19):3753-7.
    View in: PubMed
    Score: 0.015
  22. Pharmacokinetics and Pharmacodynamics of Escalating Doses of SHetA2 After Vaginal Administration to Mice. J Pharm Sci. 2018 12; 107(12):3179-3186.
    View in: PubMed
    Score: 0.015
  23. Influence of the estrus cycle of the mouse on the disposition of SHetA2 after vaginal administration. Eur J Pharm Biopharm. 2018 Sep; 130:272-280.
    View in: PubMed
    Score: 0.015
  24. Pharmacokinetics and interspecies scaling of a novel, orally-bioavailable anti-cancer drug, SHetA2. PLoS One. 2018; 13(4):e0194046.
    View in: PubMed
    Score: 0.015
  25. Anti-CD73 and anti-OX40 immunotherapy coupled with a novel biocompatible enzyme prodrug system for the treatment of recurrent, metastatic ovarian cancer. Cancer Lett. 2018 07 01; 425:174-182.
    View in: PubMed
    Score: 0.015
  26. Biologically active heteroarotinoids exhibiting anticancer activity and decreased toxicity. J Med Chem. 1997 Oct 24; 40(22):3567-83.
    View in: PubMed
    Score: 0.014
  27. Optimization of a Vaginal Suppository Formulation to Deliver SHetA2 as a Novel Treatment for Cervical Dysplasia. J Pharm Sci. 2018 02; 107(2):638-646.
    View in: PubMed
    Score: 0.014
  28. Loss of natural killer T cells promotes pancreatic cancer in LSL-KrasG12D/+ mice. Immunology. 2017 09; 152(1):36-51.
    View in: PubMed
    Score: 0.014
  29. Label-Free Real-Time Microarray Imaging of Cancer Protein-Protein Interactions and Their Inhibition by Small Molecules. Anal Chem. 2016 Mar 15; 88(6):3130-5.
    View in: PubMed
    Score: 0.013
  30. Oral toxicity and pharmacokinetic studies of SHetA2, a new chemopreventive agent, in rats and dogs. Drug Chem Toxicol. 2013 Jul; 36(3):284-95.
    View in: PubMed
    Score: 0.010
  31. Genotoxicity of the cancer chemopreventive drug candidates CP-31398, SHetA2, and phospho-ibuprofen. Mutat Res. 2012 Jul 04; 746(1):78-88.
    View in: PubMed
    Score: 0.010
  32. Wnt inhibitory factor 1 induces apoptosis and inhibits cervical cancer growth, invasion and angiogenesis in vivo. Oncogene. 2012 May 31; 31(22):2725-37.
    View in: PubMed
    Score: 0.009
  33. Metabolism of a sulfur-containing heteroarotionoid antitumor agent, SHetA2, using liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2008 Nov; 22(21):3371-81.
    View in: PubMed
    Score: 0.008
  34. CAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells. Cancer Res. 2008 Jul 01; 68(13):5335-44.
    View in: PubMed
    Score: 0.007
  35. High performance liquid chromatographic analysis and preclinical pharmacokinetics of the heteroarotinoid antitumor agent, SHetA2. Cancer Chemother Pharmacol. 2006 Nov; 58(5):561-9.
    View in: PubMed
    Score: 0.006
  36. Retinoid activation of retinoic acid receptor but not retinoid X receptor is sufficient to rescue lethal defect in retinoic acid synthesis. Proc Natl Acad Sci U S A. 2003 Jun 10; 100(12):7135-40.
    View in: PubMed
    Score: 0.005
  37. Antitumor activity of SS(dsFv)PE38 and SS1(dsFv)PE38, recombinant antimesothelin immunotoxins against human gynecologic cancers grown in organotypic culture in vitro. Clin Cancer Res. 2002 Nov; 8(11):3520-6.
    View in: PubMed
    Score: 0.005
  38. Complexity, retinoid-responsive gene networks, and bladder carcinogenesis. Adv Exp Med Biol. 1999; 462:449-67.
    View in: PubMed
    Score: 0.004
  39. A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily. Mol Cell Biol. 1994 Oct; 14(10):7025-35.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.