Patrick Gaffney to Signal Transduction
This is a "connection" page, showing publications Patrick Gaffney has written about Signal Transduction.
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TALEN-mediated enhancer knockout influences TNFAIP3 gene expression and mimics a molecular phenotype associated with systemic lupus erythematosus. Genes Immun. 2016 04; 17(3):165-70.
Score: 0.084
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An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression. PLoS Genet. 2013; 9(9):e1003750.
Score: 0.071
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Endogenous heparan sulfate and heparin modulate bone morphogenetic protein-4 signaling and activity. Am J Physiol Cell Physiol. 2008 Jun; 294(6):C1387-97.
Score: 0.049
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A20-Binding Inhibitor of NF-?B Activation 1 is a Physiologic Inhibitor of NF-?B: A Molecular Switch for Inflammation and Autoimmunity. Arthritis Rheumatol. 2015 Sep; 67(9):2292-302.
Score: 0.020
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Forward genetic screening identifies a small molecule that blocks Toxoplasma gondii growth by inhibiting both host- and parasite-encoded kinases. PLoS Pathog. 2014 Jun; 10(6):e1004180.
Score: 0.019
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CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation. Nat Genet. 2012 Nov; 44(11):1227-30.
Score: 0.017
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Effects of IRF5 lupus risk haplotype on pathways predicted to influence B cell functions. J Biomed Biotechnol. 2012; 2012:594056.
Score: 0.016
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Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK. Ann Rheum Dis. 2012 Jan; 71(1):136-42.
Score: 0.016
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A novel polymorphism of the human CD40 receptor with enhanced function. Blood. 2008 Sep 01; 112(5):1863-71.
Score: 0.012