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Patrick Gaffney to Haplotypes

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This is a "connection" page, showing publications Patrick Gaffney has written about Haplotypes.
Patrick Gaffney
Connection Strength
3.667
Haplotypes
  1. Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks. Nat Commun. 2018 07 25; 9(1):2905.
    View in: PubMed
    Score: 0.588
  2. Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus. Arthritis Rheum. 2012 Nov; 64(11):3695-705.
    View in: PubMed
    Score: 0.395
  3. A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus. Genes Immun. 2012 Jul; 13(5):380-7.
    View in: PubMed
    Score: 0.380
  4. Exon 6 variants carried on systemic lupus erythematosus (SLE) risk haplotypes modulate IRF5 function. Autoimmunity. 2011 Mar; 44(2):82-9.
    View in: PubMed
    Score: 0.339
  5. Variants on the UBE2L3/YDJC Autoimmune Disease Risk Haplotype Increase UBE2L3 Expression by Modulating CCCTC-Binding Factor and YY1 Binding. Arthritis Rheumatol. 2022 01; 74(1):163-173.
    View in: PubMed
    Score: 0.186
  6. Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus. Genome Biol. 2020 11 19; 21(1):281.
    View in: PubMed
    Score: 0.173
  7. Role of Systemic Lupus Erythematosus Risk Variants With Opposing Functional Effects as a Driver of Hypomorphic Expression of TNIP1 and Other Genes Within a Three-Dimensional Chromatin Network. Arthritis Rheumatol. 2020 05; 72(5):780-790.
    View in: PubMed
    Score: 0.165
  8. Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription. Am J Hum Genet. 2014 Apr 03; 94(4):586-98.
    View in: PubMed
    Score: 0.109
  9. An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression. PLoS Genet. 2013; 9(9):e1003750.
    View in: PubMed
    Score: 0.105
  10. Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus. Nat Genet. 2011 Mar; 43(3):253-8.
    View in: PubMed
    Score: 0.088
  11. Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations. Genes Immun. 2009 Jul; 10(5):470-7.
    View in: PubMed
    Score: 0.077
  12. Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus. Proc Natl Acad Sci U S A. 2007 Apr 17; 104(16):6758-63.
    View in: PubMed
    Score: 0.067
  13. Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE. Eur J Hum Genet. 2007 Aug; 15(8):823-30.
    View in: PubMed
    Score: 0.067
  14. Fine-mapping chromosome 20 in 230 systemic lupus erythematosus sib pair and multiplex families: evidence for genetic epistasis with chromosome 16q12. Am J Hum Genet. 2006 May; 78(5):747-758.
    View in: PubMed
    Score: 0.062
  15. Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus. Am J Hum Genet. 2002 Sep; 71(3):543-53.
    View in: PubMed
    Score: 0.048
  16. Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus. Arthritis Res. 2001; 3(5):299-305.
    View in: PubMed
    Score: 0.045
  17. Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans. Hum Mol Genet. 2018 11 01; 27(21):3813-3824.
    View in: PubMed
    Score: 0.037
  18. Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture. Arthritis Rheumatol. 2016 Apr; 68(4):932-43.
    View in: PubMed
    Score: 0.031
  19. Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression. Am J Hum Genet. 2015 May 07; 96(5):731-9.
    View in: PubMed
    Score: 0.029
  20. Genetic association of CD247 (CD3?) with SLE in a large-scale multiethnic study. Genes Immun. 2015 Mar; 16(2):142-50.
    View in: PubMed
    Score: 0.029
  21. The effect of inversion at 8p23 on BLK association with lupus in Caucasian population. PLoS One. 2014; 9(12):e115614.
    View in: PubMed
    Score: 0.029
  22. The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share. Hum Mol Genet. 2015 Jan 15; 24(2):582-96.
    View in: PubMed
    Score: 0.028
  23. Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA. Ann Rheum Dis. 2016 Jan; 75(1):242-52.
    View in: PubMed
    Score: 0.028
  24. GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. Genes Immun. 2014 Sep; 15(6):347-54.
    View in: PubMed
    Score: 0.028
  25. Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations. Hum Mol Genet. 2014 Mar 15; 23(6):1656-68.
    View in: PubMed
    Score: 0.026
  26. Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression. PLoS Genet. 2013; 9(10):e1003870.
    View in: PubMed
    Score: 0.026
  27. PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes. PLoS One. 2013; 8(8):e69404.
    View in: PubMed
    Score: 0.026
  28. Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4. PLoS Genet. 2013; 9(7):e1003554.
    View in: PubMed
    Score: 0.026
  29. Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry. J Rheumatol. 2013 Jun; 40(6):842-9.
    View in: PubMed
    Score: 0.026
  30. Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production. PLoS Genet. 2013; 9(2):e1003222.
    View in: PubMed
    Score: 0.025
  31. Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans. Am J Hum Genet. 2012 Nov 02; 91(5):778-93.
    View in: PubMed
    Score: 0.025
  32. Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups. Ann Rheum Dis. 2013 Mar; 72(3):437-44.
    View in: PubMed
    Score: 0.024
  33. Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study. Am J Hum Genet. 2012 Apr 06; 90(4):648-60.
    View in: PubMed
    Score: 0.024
  34. Effects of IRF5 lupus risk haplotype on pathways predicted to influence B cell functions. J Biomed Biotechnol. 2012; 2012:594056.
    View in: PubMed
    Score: 0.024
  35. Evaluation of TRAF6 in a large multiancestral lupus cohort. Arthritis Rheum. 2012 Jun; 64(6):1960-9.
    View in: PubMed
    Score: 0.023
  36. IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus. Ann Rheum Dis. 2012 Mar; 71(3):463-8.
    View in: PubMed
    Score: 0.023
  37. Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups. Arthritis Rheum. 2011 Sep; 63(9):2755-63.
    View in: PubMed
    Score: 0.023
  38. Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus. Arthritis Rheum. 2011 Jul; 63(7):2049-57.
    View in: PubMed
    Score: 0.023
  39. Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort. Genes Immun. 2011 Jun; 12(4):270-9.
    View in: PubMed
    Score: 0.022
  40. Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study. Am J Hum Genet. 2011 Jan 07; 88(1):83-91.
    View in: PubMed
    Score: 0.022
  41. The role of genetic variation near interferon-kappa in systemic lupus erythematosus. J Biomed Biotechnol. 2010; 2010.
    View in: PubMed
    Score: 0.021
  42. Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus. Arthritis Rheum. 2009 Apr; 60(4):1076-84.
    View in: PubMed
    Score: 0.019
  43. High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups. Arthritis Rheum. 2009 Apr; 60(4):1085-95.
    View in: PubMed
    Score: 0.019
  44. Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus. Proc Natl Acad Sci U S A. 2009 Apr 14; 106(15):6256-61.
    View in: PubMed
    Score: 0.019
  45. Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE). Hum Mol Genet. 2009 Mar 15; 18(6):1171-80.
    View in: PubMed
    Score: 0.019
  46. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet. 2008 Feb; 40(2):204-10.
    View in: PubMed
    Score: 0.018
  47. Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus. Nat Genet. 2008 Jan; 40(1):83-9.
    View in: PubMed
    Score: 0.018
  48. Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus. Novartis Found Symp. 2005; 267:145-60; discussion 160-4.
    View in: PubMed
    Score: 0.014
Connection Strength

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