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Patrick Gaffney to Humans

This is a "connection" page, showing publications Patrick Gaffney has written about Humans.
Connection Strength

1.262
  1. Variants on the UBE2L3/YDJC Autoimmune Disease Risk Haplotype Increase UBE2L3 Expression by Modulating CCCTC-Binding Factor and YY1 Binding. Arthritis Rheumatol. 2022 01; 74(1):163-173.
    View in: PubMed
    Score: 0.045
  2. Role of Systemic Lupus Erythematosus Risk Variants With Opposing Functional Effects as a Driver of Hypomorphic Expression of TNIP1 and Other Genes Within a Three-Dimensional Chromatin Network. Arthritis Rheumatol. 2020 05; 72(5):780-790.
    View in: PubMed
    Score: 0.040
  3. From association to mechanism in complex disease genetics: the role of the 3D genome. Arthritis Res Ther. 2018 09 29; 20(1):216.
    View in: PubMed
    Score: 0.036
  4. Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks. Nat Commun. 2018 07 25; 9(1):2905.
    View in: PubMed
    Score: 0.035
  5. TALEN-mediated enhancer knockout influences TNFAIP3 gene expression and mimics a molecular phenotype associated with systemic lupus erythematosus. Genes Immun. 2016 04; 17(3):165-70.
    View in: PubMed
    Score: 0.030
  6. Disease mechanisms in rheumatology--tools and pathways: defining functional genetic variants in autoimmune diseases. Arthritis Rheumatol. 2015 Jan; 67(1):1-10.
    View in: PubMed
    Score: 0.028
  7. Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription. Am J Hum Genet. 2014 Apr 03; 94(4):586-98.
    View in: PubMed
    Score: 0.026
  8. Use of next-generation DNA sequencing to analyze genetic variants in rheumatic disease. Arthritis Res Ther. 2014; 16(6):490.
    View in: PubMed
    Score: 0.026
  9. An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression. PLoS Genet. 2013; 9(9):e1003750.
    View in: PubMed
    Score: 0.025
  10. Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus. Arthritis Rheum. 2012 Nov; 64(11):3695-705.
    View in: PubMed
    Score: 0.024
  11. RBPJ mutations identified in two families affected by Adams-Oliver syndrome. Am J Hum Genet. 2012 Aug 10; 91(2):391-5.
    View in: PubMed
    Score: 0.023
  12. A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus. Genes Immun. 2012 Jul; 13(5):380-7.
    View in: PubMed
    Score: 0.023
  13. Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus. Nat Genet. 2011 Mar; 43(3):253-8.
    View in: PubMed
    Score: 0.021
  14. Exon 6 variants carried on systemic lupus erythematosus (SLE) risk haplotypes modulate IRF5 function. Autoimmunity. 2011 Mar; 44(2):82-9.
    View in: PubMed
    Score: 0.020
  15. Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat Genet. 2008 Sep; 40(9):1059-61.
    View in: PubMed
    Score: 0.018
  16. Genes associated with early development, apoptosis and cell cycle regulation define a gene expression profile of adenoid cystic carcinoma. Oral Oncol. 2006 Nov; 42(10):994-1004.
    View in: PubMed
    Score: 0.015
  17. Fine-mapping chromosome 20 in 230 systemic lupus erythematosus sib pair and multiplex families: evidence for genetic epistasis with chromosome 16q12. Am J Hum Genet. 2006 May; 78(5):747-758.
    View in: PubMed
    Score: 0.015
  18. Identification of a gene expression signature associated with recurrent disease in squamous cell carcinoma of the head and neck. Cancer Res. 2004 Jan 01; 64(1):55-63.
    View in: PubMed
    Score: 0.013
  19. Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells. Nat Commun. 2022 07 27; 13(1):4287.
    View in: PubMed
    Score: 0.012
  20. Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus. Front Immunol. 2022; 13:881332.
    View in: PubMed
    Score: 0.012
  21. Recent advances in the genetics of systemic lupus erythematosus. Rheum Dis Clin North Am. 2002 Feb; 28(1):111-26.
    View in: PubMed
    Score: 0.011
  22. Deficiencies in the DNA Binding Protein ARID3a Alter Chromatin Structures Important for Early Human Erythropoiesis. Immunohorizons. 2021 10 18; 5(10):802-817.
    View in: PubMed
    Score: 0.011
  23. CD4+?T cells from children with active juvenile idiopathic arthritis show altered chromatin features associated with transcriptional abnormalities. Sci Rep. 2021 02 17; 11(1):4011.
    View in: PubMed
    Score: 0.011
  24. Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits. J Invest Dermatol. 2021 08; 141(8):1975-1984.
    View in: PubMed
    Score: 0.011
  25. Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 01 20; 109(2):241-256.e9.
    View in: PubMed
    Score: 0.010
  26. Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus. Genome Biol. 2020 11 19; 21(1):281.
    View in: PubMed
    Score: 0.010
  27. Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31. BMC Biol. 2020 05 04; 18(1):47.
    View in: PubMed
    Score: 0.010
  28. Genome screening in human systemic lupus erythematosus: results from a second Minnesota cohort and combined analyses of 187 sib-pair families. Am J Hum Genet. 2000 Feb; 66(2):547-56.
    View in: PubMed
    Score: 0.010
  29. Association of Epstein-Barr virus serological reactivation with transitioning to systemic lupus erythematosus in at-risk individuals. Ann Rheum Dis. 2019 09; 78(9):1235-1241.
    View in: PubMed
    Score: 0.009
  30. Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients. EBioMedicine. 2019 Apr; 42:76-85.
    View in: PubMed
    Score: 0.009
  31. A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families. Proc Natl Acad Sci U S A. 1998 Dec 08; 95(25):14875-9.
    View in: PubMed
    Score: 0.009
  32. Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans. Hum Mol Genet. 2018 11 01; 27(21):3813-3824.
    View in: PubMed
    Score: 0.009
  33. Identification and replication of RNA-Seq gene network modules associated with depression severity. Transl Psychiatry. 2018 09 05; 8(1):180.
    View in: PubMed
    Score: 0.009
  34. Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking. JCI Insight. 2018 07 26; 3(14).
    View in: PubMed
    Score: 0.009
  35. A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus. Hum Mol Genet. 2018 07 01; 27(13):2392-2404.
    View in: PubMed
    Score: 0.009
  36. Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis. Genes Immun. 2019 04; 20(4):281-292.
    View in: PubMed
    Score: 0.009
  37. ßIV Spectrinopathies Cause Profound Intellectual Disability, Congenital Hypotonia, and Motor Axonal Neuropathy. Am J Hum Genet. 2018 06 07; 102(6):1158-1168.
    View in: PubMed
    Score: 0.009
  38. Association of Natural Killer Cell Ligand Polymorphism HLA-C Asn80Lys With the Development of Anti-SSA/Ro-Associated Congenital Heart Block. Arthritis Rheumatol. 2017 11; 69(11):2170-2174.
    View in: PubMed
    Score: 0.008
  39. Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly. Nat Genet. 2017 Oct; 49(10):1529-1538.
    View in: PubMed
    Score: 0.008
  40. Transancestral mapping and genetic load in systemic lupus erythematosus. Nat Commun. 2017 07 17; 8:16021.
    View in: PubMed
    Score: 0.008
  41. Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons. PLoS Genet. 2017 Jun; 13(6):e1006820.
    View in: PubMed
    Score: 0.008
  42. Polygenic risk assessment reveals pleiotropy between sarcoidosis and inflammatory disorders in the context of genetic ancestry. Genes Immun. 2017 03; 18(2):88-94.
    View in: PubMed
    Score: 0.008
  43. Association of IFIH1 and pro-inflammatory mediators: Potential new clues in SLE-associated pathogenesis. PLoS One. 2017; 12(2):e0171193.
    View in: PubMed
    Score: 0.008
  44. A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases. Nat Genet. 2017 Mar; 49(3):433-437.
    View in: PubMed
    Score: 0.008
  45. Human effector B lymphocytes express ARID3a and secrete interferon alpha. J Autoimmun. 2016 Dec; 75:130-140.
    View in: PubMed
    Score: 0.008
  46. Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus. Nat Genet. 2016 08; 48(8):940-946.
    View in: PubMed
    Score: 0.008
  47. Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus. Ann Rheum Dis. 2017 Jan; 76(1):153-158.
    View in: PubMed
    Score: 0.008
  48. Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans. Arthritis Rheumatol. 2016 05; 68(5):1197-1209.
    View in: PubMed
    Score: 0.008
  49. X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome. Arthritis Rheumatol. 2016 05; 68(5):1290-1300.
    View in: PubMed
    Score: 0.008
  50. Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture. Arthritis Rheumatol. 2016 Apr; 68(4):932-43.
    View in: PubMed
    Score: 0.008
  51. Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity. Elife. 2016 Feb 15; 5.
    View in: PubMed
    Score: 0.007
  52. Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production. Ann Rheum Dis. 2016 Nov; 75(11):2007-2013.
    View in: PubMed
    Score: 0.007
  53. Identification of a New Susceptibility Locus for Systemic Lupus Erythematosus on Chromosome 12 in Individuals of European Ancestry. Arthritis Rheumatol. 2016 Jan; 68(1):174-83.
    View in: PubMed
    Score: 0.007
  54. Gut Microbiome Diversity among Cheyenne and Arapaho Individuals from Western Oklahoma. Curr Biol. 2015 Dec 21; 25(24):3161-9.
    View in: PubMed
    Score: 0.007
  55. Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus. Clin Immunol. 2015 Dec; 161(2):157-62.
    View in: PubMed
    Score: 0.007
  56. A20-Binding Inhibitor of NF-?B Activation 1 is a Physiologic Inhibitor of NF-?B: A Molecular Switch for Inflammation and Autoimmunity. Arthritis Rheumatol. 2015 Sep; 67(9):2292-302.
    View in: PubMed
    Score: 0.007
  57. Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression. Am J Hum Genet. 2015 May 07; 96(5):731-9.
    View in: PubMed
    Score: 0.007
  58. Subsistence strategies in traditional societies distinguish gut microbiomes. Nat Commun. 2015 Mar 25; 6:6505.
    View in: PubMed
    Score: 0.007
  59. Genetic association of CD247 (CD3?) with SLE in a large-scale multiethnic study. Genes Immun. 2015 Mar; 16(2):142-50.
    View in: PubMed
    Score: 0.007
  60. The effect of inversion at 8p23 on BLK association with lupus in Caucasian population. PLoS One. 2014; 9(12):e115614.
    View in: PubMed
    Score: 0.007
  61. The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share. Hum Mol Genet. 2015 Jan 15; 24(2):582-96.
    View in: PubMed
    Score: 0.007
  62. Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA. Ann Rheum Dis. 2016 Jan; 75(1):242-52.
    View in: PubMed
    Score: 0.007
  63. Lupus nephritis susceptibility loci in women with systemic lupus erythematosus. J Am Soc Nephrol. 2014 Dec; 25(12):2859-70.
    View in: PubMed
    Score: 0.007
  64. GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. Genes Immun. 2014 Sep; 15(6):347-54.
    View in: PubMed
    Score: 0.007
  65. MHC associations with clinical and autoantibody manifestations in European SLE. Genes Immun. 2014 Apr; 15(4):210-7.
    View in: PubMed
    Score: 0.007
  66. Activating mutations in STIM1 and ORAI1 cause overlapping syndromes of tubular myopathy and congenital miosis. Proc Natl Acad Sci U S A. 2014 Mar 18; 111(11):4197-202.
    View in: PubMed
    Score: 0.007
  67. Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations. Hum Mol Genet. 2014 Mar 15; 23(6):1656-68.
    View in: PubMed
    Score: 0.006
  68. Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression. PLoS Genet. 2013; 9(10):e1003870.
    View in: PubMed
    Score: 0.006
  69. Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome. Nat Genet. 2013 Nov; 45(11):1284-92.
    View in: PubMed
    Score: 0.006
  70. ABIN1 dysfunction as a genetic basis for lupus nephritis. J Am Soc Nephrol. 2013 Nov; 24(11):1743-54.
    View in: PubMed
    Score: 0.006
  71. PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes. PLoS One. 2013; 8(8):e69404.
    View in: PubMed
    Score: 0.006
  72. Protein kinase cd deficiency causes mendelian systemic lupus erythematosus with B cell-defective apoptosis and hyperproliferation. Arthritis Rheum. 2013 Aug; 65(8):2161-71.
    View in: PubMed
    Score: 0.006
  73. Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4. PLoS Genet. 2013; 9(7):e1003554.
    View in: PubMed
    Score: 0.006
  74. Encore: Genetic Association Interaction Network centrality pipeline and application to SLE exome data. Genet Epidemiol. 2013 Sep; 37(6):614-21.
    View in: PubMed
    Score: 0.006
  75. Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry. J Rheumatol. 2013 Jun; 40(6):842-9.
    View in: PubMed
    Score: 0.006
  76. Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis. Nat Genet. 2013 Jun; 45(6):664-9.
    View in: PubMed
    Score: 0.006
  77. MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus. PLoS Genet. 2013; 9(2):e1003336.
    View in: PubMed
    Score: 0.006
  78. Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production. PLoS Genet. 2013; 9(2):e1003222.
    View in: PubMed
    Score: 0.006
  79. Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations. Arthritis Rheum. 2012 Nov; 64(11):3687-94.
    View in: PubMed
    Score: 0.006
  80. Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans. Am J Hum Genet. 2012 Nov 02; 91(5):778-93.
    View in: PubMed
    Score: 0.006
  81. CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation. Nat Genet. 2012 Nov; 44(11):1227-30.
    View in: PubMed
    Score: 0.006
  82. Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups. Ann Rheum Dis. 2013 Mar; 72(3):437-44.
    View in: PubMed
    Score: 0.006
  83. Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries. Ann Rheum Dis. 2012 Nov; 71(11):1809-14.
    View in: PubMed
    Score: 0.006
  84. Identification of novel coding mutation in C1qA gene in an African-American pedigree with lupus and C1q deficiency. Lupus. 2012 Sep; 21(10):1113-8.
    View in: PubMed
    Score: 0.006
  85. Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study. Am J Hum Genet. 2012 Apr 06; 90(4):648-60.
    View in: PubMed
    Score: 0.006
  86. Effects of IRF5 lupus risk haplotype on pathways predicted to influence B cell functions. J Biomed Biotechnol. 2012; 2012:594056.
    View in: PubMed
    Score: 0.006
  87. Contributions of mass spectrometry-based proteomics to defining cellular mechanisms and diagnostic markers for systemic lupus erythematosus. Arthritis Res Ther. 2012 Feb 20; 14(1):204.
    View in: PubMed
    Score: 0.006
  88. Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus. Arthritis Rheum. 2012 Feb; 64(2):485-92.
    View in: PubMed
    Score: 0.006
  89. Evaluation of TRAF6 in a large multiancestral lupus cohort. Arthritis Rheum. 2012 Jun; 64(6):1960-9.
    View in: PubMed
    Score: 0.006
  90. Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase. Proc Natl Acad Sci U S A. 2012 Jan 10; 109(2):E59-67.
    View in: PubMed
    Score: 0.006
  91. Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis. Genes Immun. 2012 Apr; 13(3):232-8.
    View in: PubMed
    Score: 0.006
  92. A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap. PLoS Genet. 2011 Dec; 7(12):e1002406.
    View in: PubMed
    Score: 0.006
  93. Sex chromosome aneuploidies among men with systemic lupus erythematosus. J Autoimmun. 2012 May; 38(2-3):J129-34.
    View in: PubMed
    Score: 0.006
  94. Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus. Ann Rheum Dis. 2012 May; 71(5):694-9.
    View in: PubMed
    Score: 0.006
  95. IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus. Ann Rheum Dis. 2012 Mar; 71(3):463-8.
    View in: PubMed
    Score: 0.006
  96. Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study. Arthritis Rheum. 2011 Nov; 63(11):3493-501.
    View in: PubMed
    Score: 0.006
  97. The genomics of autoimmune disease in the era of genome-wide association studies and beyond. Autoimmun Rev. 2012 Feb; 11(4):267-75.
    View in: PubMed
    Score: 0.006
  98. Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK. Ann Rheum Dis. 2012 Jan; 71(1):136-42.
    View in: PubMed
    Score: 0.006
  99. Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups. Arthritis Rheum. 2011 Sep; 63(9):2755-63.
    View in: PubMed
    Score: 0.005
  100. Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus. Arthritis Rheum. 2011 Jul; 63(7):2049-57.
    View in: PubMed
    Score: 0.005
  101. Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus. Ann Rheum Dis. 2011 Oct; 70(10):1752-7.
    View in: PubMed
    Score: 0.005
  102. Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21. Arthritis Rheum. 2011 Jun; 63(6):1689-97.
    View in: PubMed
    Score: 0.005
  103. The rs4774 CIITA missense variant is associated with risk of systemic lupus erythematosus. Genes Immun. 2011 Dec; 12(8):667-71.
    View in: PubMed
    Score: 0.005
  104. Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility. PLoS Genet. 2011 May; 7(5):e1002079.
    View in: PubMed
    Score: 0.005
  105. Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. PLoS Genet. 2011 Mar; 7(3):e1001323.
    View in: PubMed
    Score: 0.005
  106. Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes. PLoS Genet. 2011 Feb; 7(2):e1001311.
    View in: PubMed
    Score: 0.005
  107. Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort. Genes Immun. 2011 Jun; 12(4):270-9.
    View in: PubMed
    Score: 0.005
  108. Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study. Am J Hum Genet. 2011 Jan 07; 88(1):83-91.
    View in: PubMed
    Score: 0.005
  109. The role of genetic variation near interferon-kappa in systemic lupus erythematosus. J Biomed Biotechnol. 2010; 2010.
    View in: PubMed
    Score: 0.005
  110. Analysis of maternal-offspring HLA compatibility, parent-of-origin effects, and noninherited maternal antigen effects for HLA-DRB1 in systemic lupus erythematosus. Arthritis Rheum. 2010 Jun; 62(6):1712-7.
    View in: PubMed
    Score: 0.005
  111. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. PLoS Genet. 2009 Oct; 5(10):e1000696.
    View in: PubMed
    Score: 0.005
  112. A polymorphism within IL21R confers risk for systemic lupus erythematosus. Arthritis Rheum. 2009 Aug; 60(8):2402-7.
    View in: PubMed
    Score: 0.005
  113. European population substructure is associated with mucocutaneous manifestations and autoantibody production in systemic lupus erythematosus. Arthritis Rheum. 2009 Aug; 60(8):2448-56.
    View in: PubMed
    Score: 0.005
  114. Identification of new SLE-associated genes with a two-step Bayesian study design. Genes Immun. 2009 Jul; 10(5):446-56.
    View in: PubMed
    Score: 0.005
  115. Peripheral blood gene expression profiling in Sjögren's syndrome. Genes Immun. 2009 Jun; 10(4):285-96.
    View in: PubMed
    Score: 0.005
  116. Variation in the upstream region of P-Selectin (SELP) is a risk factor for SLE. Genes Immun. 2009 Jul; 10(5):404-13.
    View in: PubMed
    Score: 0.005
  117. Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing. Genes Immun. 2009 Jul; 10(5):457-69.
    View in: PubMed
    Score: 0.005
  118. Variation in the ATP-binding cassette transporter 2 gene is a separate risk factor for systemic lupus erythematosus within the MHC. Genes Immun. 2009 Jun; 10(4):350-5.
    View in: PubMed
    Score: 0.005
  119. Genetic associations of LYN with systemic lupus erythematosus. Genes Immun. 2009 Jul; 10(5):397-403.
    View in: PubMed
    Score: 0.005
  120. Replication of the BANK1 genetic association with systemic lupus erythematosus in a European-derived population. Genes Immun. 2009 Jul; 10(5):531-8.
    View in: PubMed
    Score: 0.005
  121. Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus. Arthritis Rheum. 2009 Apr; 60(4):1076-84.
    View in: PubMed
    Score: 0.005
  122. High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups. Arthritis Rheum. 2009 Apr; 60(4):1085-95.
    View in: PubMed
    Score: 0.005
  123. Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE). Hum Mol Genet. 2009 Mar 15; 18(6):1171-80.
    View in: PubMed
    Score: 0.005
  124. A novel polymorphism of the human CD40 receptor with enhanced function. Blood. 2008 Sep 01; 112(5):1863-71.
    View in: PubMed
    Score: 0.004
  125. Endogenous heparan sulfate and heparin modulate bone morphogenetic protein-4 signaling and activity. Am J Physiol Cell Physiol. 2008 Jun; 294(6):C1387-97.
    View in: PubMed
    Score: 0.004
  126. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet. 2008 Feb; 40(2):204-10.
    View in: PubMed
    Score: 0.004
  127. Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus. Proc Natl Acad Sci U S A. 2007 Apr 17; 104(16):6758-63.
    View in: PubMed
    Score: 0.004
  128. Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE. Eur J Hum Genet. 2007 Aug; 15(8):823-30.
    View in: PubMed
    Score: 0.004
  129. Meta-analysis of genome-wide linkage studies of systemic lupus erythematosus. Genes Immun. 2006 Oct; 7(7):609-14.
    View in: PubMed
    Score: 0.004
  130. Familial aggregation and linkage analysis of autoantibody traits in pedigrees multiplex for systemic lupus erythematosus. Genes Immun. 2006 Jul; 7(5):417-32.
    View in: PubMed
    Score: 0.004
  131. Gene expression profiling in human autoimmunity. Immunol Rev. 2006 Apr; 210:120-37.
    View in: PubMed
    Score: 0.004
  132. Molecular imaging of human thrombus with computed tomography. Acad Radiol. 2005 May; 12 Suppl 1:S9-13.
    View in: PubMed
    Score: 0.004
  133. Fine mapping chromosome 16q12 in a collection of 231 systemic lupus erythematosus sibpair and multiplex families. Genes Immun. 2005 Feb; 6(1):19-23.
    View in: PubMed
    Score: 0.003
  134. Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus. Novartis Found Symp. 2005; 267:145-60; discussion 160-4.
    View in: PubMed
    Score: 0.003
  135. Quantitative "magnetic resonance immunohistochemistry" with ligand-targeted (19)F nanoparticles. Magn Reson Med. 2004 Dec; 52(6):1255-62.
    View in: PubMed
    Score: 0.003
  136. Expression levels for many genes in human peripheral blood cells are highly sensitive to ex vivo incubation. Genes Immun. 2004 Aug; 5(5):347-53.
    View in: PubMed
    Score: 0.003
  137. Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. Am J Hum Genet. 2004 Sep; 75(3):504-7.
    View in: PubMed
    Score: 0.003
  138. Keys to unlocking the mysteries of rheumatic autoimmune disease. Minn Med. 2004 May; 87(5):46-51.
    View in: PubMed
    Score: 0.003
  139. The use of microarrays to study autoimmunity. J Investig Dermatol Symp Proc. 2004 Jan; 9(1):18-22.
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  140. Improved molecular imaging contrast agent for detection of human thrombus. Magn Reson Med. 2003 Aug; 50(2):411-6.
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  141. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2610-5.
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  142. Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus. Am J Hum Genet. 2002 Sep; 71(3):543-53.
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  143. Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus. Arthritis Res. 2001; 3(5):299-305.
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  144. Genome scan of human systemic lupus erythematosus by regression modeling: evidence of linkage and epistasis at 4p16-15.2. Am J Hum Genet. 2000 Dec; 67(6):1460-9.
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  145. PARP alleles and SLE: failure to confirm association with disease susceptibility. J Clin Invest. 2000 Jun; 105(11):1501-2.
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  146. PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2. Curr Biol. 1999 Apr 22; 9(8):393-404.
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  148. 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase. Curr Biol. 1997 Oct 01; 7(10):776-89.
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Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.