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Connection

Jonathan Wren to Aging

This is a "connection" page, showing publications Jonathan Wren has written about Aging.
Connection Strength

1.985
  1. Many chronological aging clocks can be found throughout the epigenome: Implications for quantifying biological aging. Aging Cell. 2021 11; 20(11):e13492.
    View in: PubMed
    Score: 0.454
  2. Oklahoma Nathan Shock Aging Center - assessing the basic biology of aging from genetics to protein and function. Geroscience. 2021 10; 43(5):2183-2203.
    View in: PubMed
    Score: 0.113
  3. Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects. Geroscience. 2019 08; 41(4):419-439.
    View in: PubMed
    Score: 0.098
  4. Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline. J Gerontol A Biol Sci Med Sci. 2019 02 15; 74(3):290-298.
    View in: PubMed
    Score: 0.094
  5. Endothelial dysfunction and angiogenesis impairment in the ageing vasculature. Nat Rev Cardiol. 2018 09; 15(9):555-565.
    View in: PubMed
    Score: 0.091
  6. Profiling of m6A RNA modifications identified an age-associated regulation of AGO2 mRNA stability. Aging Cell. 2018 06; 17(3):e12753.
    View in: PubMed
    Score: 0.089
  7. Sexually divergent DNA methylation patterns with hippocampal aging. Aging Cell. 2017 12; 16(6):1342-1352.
    View in: PubMed
    Score: 0.086
  8. Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype. Aging Cell. 2017 06; 16(3):469-479.
    View in: PubMed
    Score: 0.083
  9. Effects of transgenic methionine sulfoxide reductase A (MsrA) expression on lifespan and age-dependent changes in metabolic function in mice. Redox Biol. 2016 12; 10:251-256.
    View in: PubMed
    Score: 0.080
  10. Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging. Age (Dordr). 2016 Aug; 38(4):273-289.
    View in: PubMed
    Score: 0.080
  11. IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis. Age (Dordr). 2016 Aug; 38(4):239-258.
    View in: PubMed
    Score: 0.079
  12. Bisulfite oligonucleotide-capture sequencing for targeted base- and strand-specific absolute 5-methylcytosine quantitation. Age (Dordr). 2016 Jun; 38(3):49.
    View in: PubMed
    Score: 0.078
  13. CNS-wide Sexually Dimorphic Induction of the Major Histocompatibility Complex 1 Pathway With Aging. J Gerontol A Biol Sci Med Sci. 2017 01; 72(1):16-29.
    View in: PubMed
    Score: 0.076
  14. The Achilles' heel of senescent cells: from transcriptome to senolytic drugs. Aging Cell. 2015 Aug; 14(4):644-58.
    View in: PubMed
    Score: 0.072
  15. Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection. Aging Cell. 2015 Jun; 14(3):400-8.
    View in: PubMed
    Score: 0.071
  16. Hippocampal subregions exhibit both distinct and shared transcriptomic responses to aging and nonneurodegenerative cognitive decline. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1311-24.
    View in: PubMed
    Score: 0.068
  17. Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats. Am J Physiol Heart Circ Physiol. 2014 Aug 01; 307(3):H292-306.
    View in: PubMed
    Score: 0.068
  18. Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1339-52.
    View in: PubMed
    Score: 0.068
  19. Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling. Geroscience. 2022 04; 44(2):953-981.
    View in: PubMed
    Score: 0.029
  20. Pharmacologic treatment with OKN-007 reduces alpha-motor neuron loss in spinal cord of aging mice. Geroscience. 2022 02; 44(1):67-81.
    View in: PubMed
    Score: 0.029
  21. Characterization of the SARS-CoV-2 Host Response in Primary Human Airway Epithelial Cells from Aged Individuals. Viruses. 2021 08 12; 13(8).
    View in: PubMed
    Score: 0.028
  22. Calorie restriction prevents age-related changes in the intestinal microbiota. Aging (Albany NY). 2021 03 10; 13(5):6298-6329.
    View in: PubMed
    Score: 0.027
  23. The role of DNA methylation in epigenetics of aging. Pharmacol Ther. 2019 03; 195:172-185.
    View in: PubMed
    Score: 0.023
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.