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This is a "connection" page, showing publications co-authored by Anna Csiszar and Stefano Tarantini.
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  1. Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype. Geroscience. 2021 10; 43(5):2387-2394.
    View in: PubMed
    Score: 0.709
  2. Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice. Geroscience. 2019 10; 41(5):609-617.
    View in: PubMed
    Score: 0.626
  3. Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice: Translational Relevance of Decreased Cadence and Increased Gait Variability. J Gerontol A Biol Sci Med Sci. 2019 08 16; 74(9):1417-1421.
    View in: PubMed
    Score: 0.618
  4. Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype. J Gerontol A Biol Sci Med Sci. 2018 06 14; 73(7):853-863.
    View in: PubMed
    Score: 0.570
  5. Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline. Exp Gerontol. 2017 08; 94:52-58.
    View in: PubMed
    Score: 0.510
  6. Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging. Age (Dordr). 2016 Aug; 38(4):273-289.
    View in: PubMed
    Score: 0.504
  7. IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis. Age (Dordr). 2016 Aug; 38(4):239-258.
    View in: PubMed
    Score: 0.503
  8. Circulating factors induced by time-restricted eating drive metabolic reprogramming in endothelial cells. Geroscience. 2026 Jul 24.
    View in: PubMed
    Score: 0.250
  9. Time-restricted feeding rejuvenates cerebrovascular function and preserves cognition during aging. Res Sq. 2026 Jun 02.
    View in: PubMed
    Score: 0.247
  10. Rethinking dietary fat for the aging brain: the roles or ketosis and fat quality in cerebrovascular aging and VCID. Crit Rev Food Sci Nutr. 2026 May 23; 1-17.
    View in: PubMed
    Score: 0.247
  11. Focused ultrasound opens the blood-brain barrier and reveals an age-dependent dissociation between resting cerebral blood flow and neurovascular coupling. J Cereb Blood Flow Metab. 2026 May 13; 271678X261447782.
    View in: PubMed
    Score: 0.246
  12. Multi-contrast optical coherence tomography for in vivo visualization and quantification of vascular features and collagen in mouse ovaries in aging. Biomed Opt Express. 2026 Jun 01; 17(6):2897-2913.
    View in: PubMed
    Score: 0.246
  13. Targeting senescence mitigates the deleterious effects of midlife obesity on neurovascular function by partially restoring blood-brain barrier integrity and neurovascular coupling. J Cereb Blood Flow Metab. 2026 May 05; 271678X261444196.
    View in: PubMed
    Score: 0.246
  14. LDL oxidation and cerebrovascular aging: mechanisms of endothelial dysfunction, inflammation, and vascular cognitive impairment and dementia. Redox Biol. 2026 May; 92:104118.
    View in: PubMed
    Score: 0.243
  15. Rejuvenation of the Aged Cerebrovascular System via Protein Corona-Guided Fusogenic Liposome Delivery. bioRxiv. 2026 Mar 09.
    View in: PubMed
    Score: 0.243
  16. Plasma-based strategies for systemic rejuvenation: critical perspectives on clinical translation. Geroscience. 2026 Feb 20.
    View in: PubMed
    Score: 0.243
  17. Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging. Aging Cell. 2026 Feb; 25(2):e70372.
    View in: PubMed
    Score: 0.242
  18. A Minimally Invasive Framework Reveals Region-Specific Cerebrovascular Remodeling in Aging Using Intravital Functional Ultrasound Imaging and Ultrasound Localization Microscopy (fUS-ULM). Adv Sci (Weinh). 2025 Sep 14; e10754.
    View in: PubMed
    Score: 0.235
  19. Review of the Role of TRAF7 in Brain Endothelial Integrity and Cerebrovascular Aging. Life (Basel). 2025 Aug 12; 15(8).
    View in: PubMed
    Score: 0.234
  20. Senescent Endothelial Cells in Cerebral Microcirculation Are Key Drivers of Age-Related Blood-Brain Barrier Disruption, Microvascular Rarefaction, and Neurovascular Coupling Impairment in Mice. Aging Cell. 2025 Apr 01; e70048.
    View in: PubMed
    Score: 0.228
  21. Functional ultrasound imaging reveals microvascular rarefaction, decreased cerebral blood flow, and impaired neurovascular coupling in a mouse model of paclitaxel-induced chemobrain. Geroscience. 2025 Mar 25.
    View in: PubMed
    Score: 0.228
  22. Persisting blood-brain barrier disruption following cisplatin treatment in a mouse model of chemotherapy-associated cognitive impairment. Geroscience. 2025 Feb 21.
    View in: PubMed
    Score: 0.226
  23. Cisplatin and methotrexate induce brain microvascular endothelial and microglial senescence in mouse models of chemotherapy-associated cognitive impairment. Geroscience. 2025 Feb 20.
    View in: PubMed
    Score: 0.226
  24. Endothelial Colony-Forming Cells (ECFCs) in cerebrovascular aging: Focus on the pathogenesis of Vascular Cognitive Impairment and Dementia (VCID), and treatment prospects. Ageing Res Rev. 2025 Jan 28; 104:102672.
    View in: PubMed
    Score: 0.225
  25. Longitudinal detection of gait alterations associated with hypertension-induced cerebral microhemorrhages in mice: predictive role of stride length and stride time asymmetry and increased gait entropy. Geroscience. 2024 Jun 25.
    View in: PubMed
    Score: 0.216
  26. Novel intravital approaches to quantify deep vascular structure and perfusion in the aging mouse brain using ultrasound localization microscopy (ULM). J Cereb Blood Flow Metab. 2024 Jun 13; 271678X241260526.
    View in: PubMed
    Score: 0.216
  27. Transcriptomic signatures of time-restricted feeding (TRF) in cerebrovascular aging and cognitive health. Vascul Pharmacol. 2024 Jun; 155:107338.
    View in: PubMed
    Score: 0.215
  28. Atherosclerotic burden and cerebral small vessel disease: exploring the link through microvascular aging and cerebral microhemorrhages. Geroscience. 2024 Apr 19.
    View in: PubMed
    Score: 0.214
  29. Accelerated Aging Induced by an Unhealthy High-Fat Diet: Initial Evidence for the Role of Nrf2 Deficiency and Impaired Stress Resilience in Cellular Senescence. Nutrients. 2024 Mar 26; 16(7).
    View in: PubMed
    Score: 0.213
  30. PCSK9: an emerging player in cardiometabolic aging and its potential as a therapeutic target and biomarker. Geroscience. 2023 Dec 18.
    View in: PubMed
    Score: 0.209
  31. Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)-induced chemobrain. Aging Cell. 2023 07; 22(7):e13832.
    View in: PubMed
    Score: 0.201
  32. Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain. Geroscience. 2022 04; 44(2):661-681.
    View in: PubMed
    Score: 0.183
  33. Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice. Geroscience. 2021 10; 43(5):2427-2440.
    View in: PubMed
    Score: 0.178
  34. Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice. Geroscience. 2021 10; 43(5):2611-2619.
    View in: PubMed
    Score: 0.178
  35. Early manifestation of gait alterations in the Tg2576 mouse model of Alzheimer's disease. Geroscience. 2021 08; 43(4):1947-1957.
    View in: PubMed
    Score: 0.176
  36. Hypertension-induced cognitive impairment: from pathophysiology to public health. Nat Rev Nephrol. 2021 Oct; 17(10):639-654.
    View in: PubMed
    Score: 0.175
  37. IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging. Geroscience. 2021 04; 43(2):901-911.
    View in: PubMed
    Score: 0.172
  38. Midlife Obesity Impairs Neurovascular Coupling Responses. Obesity (Silver Spring). 2021 01; 29(1):17.
    View in: PubMed
    Score: 0.169
  39. Age-related alterations in the cerebrovasculature affect neurovascular coupling and BOLD fMRI responses: Insights from animal models of aging. Psychophysiology. 2021 07; 58(7):e13718.
    View in: PubMed
    Score: 0.168
  40. Companion animals likely do not spread COVID-19 but may get infected themselves. Geroscience. 2020 10; 42(5):1229-1236.
    View in: PubMed
    Score: 0.165
  41. Mechanisms of Vascular Aging, A Geroscience Perspective: JACC Focus Seminar. J Am Coll Cardiol. 2020 03 03; 75(8):931-941.
    View in: PubMed
    Score: 0.160
  42. Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging. Geroscience. 2019 10; 41(5):533-542.
    View in: PubMed
    Score: 0.157
  43. Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases. Geroscience. 2019 12; 41(6):727-738.
    View in: PubMed
    Score: 0.157
  44. Potential Adverse Cardiovascular Effects of Treatment With Fluoxetine and Other Selective Serotonin Reuptake Inhibitors (SSRIs) in Patients With Geriatric Depression: Implications for Atherogenesis and Cerebromicrovascular Dysregulation. Front Genet. 2019; 10:898.
    View in: PubMed
    Score: 0.155
  45. Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research. Geroscience. 2019 04; 41(2):209-227.
    View in: PubMed
    Score: 0.151
  46. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019 06; 24:101192.
    View in: PubMed
    Score: 0.151
  47. Role of endothelial NAD+ deficiency in age-related vascular dysfunction. Am J Physiol Heart Circ Physiol. 2019 06 01; 316(6):H1253-H1266.
    View in: PubMed
    Score: 0.150
  48. IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging. J Gerontol A Biol Sci Med Sci. 2019 03 14; 74(4):446-454.
    View in: PubMed
    Score: 0.150
  49. Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline. J Gerontol A Biol Sci Med Sci. 2019 02 15; 74(3):290-298.
    View in: PubMed
    Score: 0.149
  50. Advances and challenges in geroscience research: An update. Physiol Int. 2018 Dec 01; 105(4):298-308.
    View in: PubMed
    Score: 0.147
  51. Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation. Geroscience. 2018 12; 40(5-6):513-521.
    View in: PubMed
    Score: 0.147
  52. Mechanisms of Vascular Aging. Circ Res. 2018 09 14; 123(7):849-867.
    View in: PubMed
    Score: 0.145
  53. Endothelial dysfunction and angiogenesis impairment in the ageing vasculature. Nat Rev Cardiol. 2018 09; 15(9):555-565.
    View in: PubMed
    Score: 0.145
  54. Correction to: Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice. Geroscience. 2018 04; 40(2):219.
    View in: PubMed
    Score: 0.140
  55. Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice. Aging Cell. 2018 04; 17(2).
    View in: PubMed
    Score: 0.139
  56. Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice. Geroscience. 2017 12; 39(5-6):601-614.
    View in: PubMed
    Score: 0.138
  57. Connective tissue growth factor (CTGF) in age-related vascular pathologies. Geroscience. 2017 12; 39(5-6):491-498.
    View in: PubMed
    Score: 0.135
  58. Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease. Geroscience. 2017 Aug; 39(4):359-372.
    View in: PubMed
    Score: 0.135
  59. Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer's disease using functional laser speckle contrast imaging. Geroscience. 2017 Aug; 39(4):465-473.
    View in: PubMed
    Score: 0.133
  60. Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype. Aging Cell. 2017 06; 16(3):469-479.
    View in: PubMed
    Score: 0.131
  61. Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice. J Cereb Blood Flow Metab. 2015 Nov; 35(11):1871-81.
    View in: PubMed
    Score: 0.116
  62. Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats. Am J Physiol Heart Circ Physiol. 2014 Aug 01; 307(3):H292-306.
    View in: PubMed
    Score: 0.108
  63. Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1339-52.
    View in: PubMed
    Score: 0.108
  64. Spatial transcriptome mapping identifies Ppara-Anxa2 cross-talk in microplastic-induced hepatotoxicity. Sci Adv. 2026 Jun 19; 12(25):eaec8681.
    View in: PubMed
    Score: 0.062
  65. Brain senescence drives sarcopenia-like transcriptomic remodeling in skeletal muscle. Geroscience. 2026 May 14.
    View in: PubMed
    Score: 0.062
  66. Age- and cognitive load-related variability and entropy of gait: integrating coefficient of variation, median absolute deviation, and permutation entropy of spatiotemporal parameters into the Semmelweis Study gait assessment framework. Geroscience. 2026 May 08.
    View in: PubMed
    Score: 0.062
  67. Young blood-induced rejuvenation of neurovascular coupling involves endothelial IGF-1/IGF-1R signaling: evidence from heterochronic parabiosis using endothelial IGF-1R deficient and systemic IGF-1 knockdown mice. Geroscience. 2026 Feb 20.
    View in: PubMed
    Score: 0.061
  68. Irradiation-induced brain senescence accelerates cardiac aging via systemic mechanisms: insights from transcriptomic profiling. Geroscience. 2026 Feb; 48(1):951-971.
    View in: PubMed
    Score: 0.059
  69. Age-related and dual task-induced gait alterations and asymmetry: optimizing the Semmelweis Study gait assessment protocol. Geroscience. 2025 Jun 06.
    View in: PubMed
    Score: 0.058
  70. Impacts of systemic milieu on cerebrovascular and brain aging: insights from heterochronic parabiosis, blood exchange, and plasma transfer experiments. Geroscience. 2025 May 23.
    View in: PubMed
    Score: 0.058
  71. Effects of NAD+ supplementation with oral nicotinamide riboside on vascular health and cognitive function in older adults with peripheral artery disease: Results from a pilot 4-week open-label clinical trial. J Pharmacol Exp Ther. 2025 Jul; 392(7):103607.
    View in: PubMed
    Score: 0.057
  72. Endothelial IGF- 1R deficiency disrupts microvascular homeostasis, impairing skeletal muscle perfusion and endurance: implications for age-related sarcopenia. Geroscience. 2025 Apr 08.
    View in: PubMed
    Score: 0.057
  73. Aging, mitochondrial dysfunction, and cerebral microhemorrhages: a preclinical evaluation of SS-31 (elamipretide) and development of a high-throughput machine learning-driven imaging pipeline for cerebromicrovascular protection therapeutic screening. Geroscience. 2025 Apr 02.
    View in: PubMed
    Score: 0.057
  74. Transcriptomic profiling of senescence effects on blood-brain barrier-related gene expression in brain capillary endothelial cells in a mouse model of paclitaxel-induced chemobrain. Geroscience. 2025 Feb 20.
    View in: PubMed
    Score: 0.057
  75. Chronic ?3 adrenergic agonist treatment improves neurovascular coupling responses, attenuates blood-brain barrier leakage and neuroinflammation, and enhances cognition in aged mice. Aging (Albany NY). 2025 Feb 19; null.
    View in: PubMed
    Score: 0.057
  76. Sex-specific mechanisms in vascular aging: exploring cellular and molecular pathways in the pathogenesis of age-related cardiovascular and cerebrovascular diseases. Geroscience. 2025 Jan 03.
    View in: PubMed
    Score: 0.056
  77. COVID-19 Exacerbates Neurovascular Uncoupling and Contributes to Endothelial Dysfunction in Patients with Mild Cognitive Impairment. Biomolecules. 2024 Dec 18; 14(12).
    View in: PubMed
    Score: 0.056
  78. Advancing prediction of age-related vascular cognitive impairment based on peripheral and retinal vascular health in a pilot study: a novel comprehensive assessment developed for a prospective workplace-based cohort (The Semmelweis Study). Geroscience. 2024 Nov 27.
    View in: PubMed
    Score: 0.056
  79. Energy metabolism dysregulation, cerebrovascular aging, and time-restricted eating: Current evidence and proof-of-concept findings. PNAS Nexus. 2024 Nov; 3(11):pgae505.
    View in: PubMed
    Score: 0.055
  80. Chronic ?3-AR stimulation activates distinct thermogenic mechanisms in brown and white adipose tissue and improves systemic metabolism in aged mice. Aging Cell. 2024 Aug 23; e14321.
    View in: PubMed
    Score: 0.055
  81. Chronic ?3 adrenergic agonist treatment improves brain microvascular endothelial function and cognition in aged mice. bioRxiv. 2024 Jul 13.
    View in: PubMed
    Score: 0.054
  82. The effects of time restricted feeding on age-related changes in the mouse retina. Exp Gerontol. 2024 Sep; 194:112510.
    View in: PubMed
    Score: 0.054
  83. The metabolic benefits of thermogenic stimulation are preserved in aging. bioRxiv. 2024 Jul 04.
    View in: PubMed
    Score: 0.054
  84. Neurovascular coupling, functional connectivity, and cerebrovascular endothelial extracellular vesicles as biomarkers of mild cognitive impairment. Alzheimers Dement. 2024 Jul 03.
    View in: PubMed
    Score: 0.054
  85. Linking peripheral atherosclerosis to blood-brain barrier disruption: elucidating its role as a manifestation of cerebral small vessel disease in vascular cognitive impairment. Geroscience. 2024 Jun 03.
    View in: PubMed
    Score: 0.054
  86. Young blood-mediated cerebromicrovascular rejuvenation through heterochronic parabiosis: enhancing blood-brain barrier integrity and capillarization in the aged mouse brain. Geroscience. 2024 May 10.
    View in: PubMed
    Score: 0.054
  87. Neurovascular coupling impairment as a mechanism for cognitive deficits in COVID-19. Brain Commun. 2024; 6(2):fcae080.
    View in: PubMed
    Score: 0.053
  88. Irradiation-induced hair graying in mice: an experimental model to evaluate the effectiveness of interventions targeting oxidative stress, DNA damage prevention, and cellular senescence. Geroscience. 2024 Jan 06.
    View in: PubMed
    Score: 0.052
  89. Dimension-based quantification of aging-associated cerebral microvasculature determined by optical coherence tomography and two-photon microscopy. J Biophotonics. 2024 Jan 04; e202300409.
    View in: PubMed
    Score: 0.052
  90. Impaired Neurovascular Coupling and Increased Functional Connectivity in the Frontal Cortex Predict Age-Related Cognitive Dysfunction. Adv Sci (Weinh). 2023 Dec 28; e2303516.
    View in: PubMed
    Score: 0.052
  91. Rejuvenation of cerebromicrovascular function in aged mice through heterochronic parabiosis: insights into neurovascular coupling and the impact of young blood factors. Geroscience. 2023 Dec 21.
    View in: PubMed
    Score: 0.052
  92. Endothelial deficiency of insulin-like growth factor-1 receptor leads to blood-brain barrier disruption and accelerated endothelial senescence in mice, mimicking aspects of the brain aging phenotype. Microcirculation. 2023 Dec 11; e12840.
    View in: PubMed
    Score: 0.052
  93. Preventing spontaneous cerebral microhemorrhages in aging mice: a novel approach targeting cellular senescence with ABT263/navitoclax. Geroscience. 2023 Dec 04.
    View in: PubMed
    Score: 0.052
  94. Survival and longevity of European rulers: geographical influences and exploring potential factors, including the Mediterranean diet - a historical analysis from 1354 to the twentieth century. Geroscience. 2023 Nov 28.
    View in: PubMed
    Score: 0.052
  95. Whole brain irradiation-induced endothelial dysfunction in the mouse brain. Geroscience. 2023 Nov 13.
    View in: PubMed
    Score: 0.052
  96. The Role of Methionine-Rich Diet in Unhealthy Cerebrovascular and Brain Aging: Mechanisms and Implications for Cognitive Impairment. Nutrients. 2023 Nov 03; 15(21).
    View in: PubMed
    Score: 0.052
  97. The Nociceptin/Orphanin FQ peptide receptor antagonist, SB-612111, improves cerebral blood flow in a rat model of traumatic brain injury. Front Pharmacol. 2023; 14:1272969.
    View in: PubMed
    Score: 0.052
  98. Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures. Geroscience. 2023 Sep 09.
    View in: PubMed
    Score: 0.051
  99. Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain. Geroscience. 2023 Aug 29.
    View in: PubMed
    Score: 0.051
  100. Vascular mechanisms leading to progression of mild cognitive impairment to dementia after COVID-19: Protocol and methodology of a prospective longitudinal observational study. PLoS One. 2023; 18(8):e0289508.
    View in: PubMed
    Score: 0.051
  101. Imaging the time course, morphology, neuronal tissue compression, and resolution of cerebral microhemorrhages in mice using intravital two-photon microscopy: insights into arteriolar, capillary, and venular origin. Geroscience. 2023 Jun 20.
    View in: PubMed
    Score: 0.050
  102. Cerebral small vessel disease pathology in COVID-19 patients: A systematic review. Ageing Res Rev. 2023 07; 88:101962.
    View in: PubMed
    Score: 0.050
  103. Measurements of cerebral microvascular blood flow, oxygenation, and morphology in a mouse model of whole-brain irradiation-induced cognitive impairment by two-photon microscopy and optical coherence tomography: evidence for microvascular injury in the cerebral white matter. Geroscience. 2023 Feb 16.
    View in: PubMed
    Score: 0.049
  104. Gait variability predicts cognitive impairment in older adults with subclinical cerebral small vessel disease. Front Aging Neurosci. 2022; 14:1052451.
    View in: PubMed
    Score: 0.048
  105. Microvascular dysfunction and neurovascular uncoupling are exacerbated in peripheral artery disease, increasing the risk of cognitive decline in older adults. Am J Physiol Heart Circ Physiol. 2022 06 01; 322(6):H924-H935.
    View in: PubMed
    Score: 0.046
  106. Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging. Front Aging Neurosci. 2022; 14:788296.
    View in: PubMed
    Score: 0.046
  107. Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling. Geroscience. 2022 04; 44(2):953-981.
    View in: PubMed
    Score: 0.046
  108. Cerebral venous congestion exacerbates cerebral microhemorrhages in mice. Geroscience. 2022 04; 44(2):805-816.
    View in: PubMed
    Score: 0.046
  109. Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses. Sci Rep. 2021 10 25; 11(1):20994.
    View in: PubMed
    Score: 0.045
  110. Animal reservoirs of SARS-CoV-2: calculable COVID-19 risk for older adults from animal to human transmission. Geroscience. 2021 10; 43(5):2305-2320.
    View in: PubMed
    Score: 0.044
  111. Sleep deprivation alters task-related changes in functional connectivity of the frontal cortex: A near-infrared spectroscopy study. Brain Behav. 2021 08; 11(8):e02135.
    View in: PubMed
    Score: 0.044
  112. Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults. PLoS One. 2021; 16(5):e0250043.
    View in: PubMed
    Score: 0.044
  113. Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by longitudinal intravital two-photon microscopy and optical coherence tomography. Am J Physiol Heart Circ Physiol. 2021 04 01; 320(4):H1370-H1392.
    View in: PubMed
    Score: 0.043
  114. Obesity-induced cognitive impairment in older adults: a microvascular perspective. Am J Physiol Heart Circ Physiol. 2021 02 01; 320(2):H740-H761.
    View in: PubMed
    Score: 0.042
  115. Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling. Geroscience. 2021 02; 43(1):197-212.
    View in: PubMed
    Score: 0.042
  116. Increases in hypertension-induced cerebral microhemorrhages exacerbate gait dysfunction in a mouse model of Alzheimer's disease. Geroscience. 2020 12; 42(6):1685-1698.
    View in: PubMed
    Score: 0.041
  117. Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain. Geroscience. 2020 04; 42(2):429-444.
    View in: PubMed
    Score: 0.040
  118. Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood. Geroscience. 2020 04; 42(2):727-748.
    View in: PubMed
    Score: 0.040
  119. Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020 04; 42(2):527-546.
    View in: PubMed
    Score: 0.040
  120. Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation-induced impairment of neurovascular coupling responses protecting cognitive function in mice. Geroscience. 2020 04; 42(2):409-428.
    View in: PubMed
    Score: 0.040
  121. Microvascular contributions to age-related macular degeneration (AMD): from mechanisms of choriocapillaris aging to novel interventions. Geroscience. 2019 12; 41(6):813-845.
    View in: PubMed
    Score: 0.039
  122. Cerebral venous congestion promotes blood-brain barrier disruption and neuroinflammation, impairing cognitive function in mice. Geroscience. 2019 10; 41(5):575-589.
    View in: PubMed
    Score: 0.039
  123. Assessment of age-related decline of neurovascular coupling responses by functional near-infrared spectroscopy (fNIRS) in humans. Geroscience. 2019 10; 41(5):495-509.
    View in: PubMed
    Score: 0.039
  124. Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice. Geroscience. 2019 12; 41(6):711-725.
    View in: PubMed
    Score: 0.039
  125. Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects. Geroscience. 2019 08; 41(4):419-439.
    View in: PubMed
    Score: 0.039
  126. Age-related impairment of neurovascular coupling responses: a dynamic vessel analysis (DVA)-based approach to measure decreased flicker light stimulus-induced retinal arteriolar dilation in healthy older adults. Geroscience. 2019 06; 41(3):341-349.
    View in: PubMed
    Score: 0.038
  127. Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment. Geroscience. 2019 10; 41(5):619-630.
    View in: PubMed
    Score: 0.038
  128. Age-related decline in peripheral vascular health predicts cognitive impairment. Geroscience. 2019 04; 41(2):125-136.
    View in: PubMed
    Score: 0.038
  129. Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment. Am J Physiol Heart Circ Physiol. 2019 05 01; 316(5):H1124-H1140.
    View in: PubMed
    Score: 0.037
  130. Repeated Valsalva maneuvers promote symptomatic manifestations of cerebral microhemorrhages: implications for the pathogenesis of vascular cognitive impairment in older adults. Geroscience. 2018 12; 40(5-6):485-496.
    View in: PubMed
    Score: 0.036
  131. Short-term weight loss reverses obesity-induced microvascular endothelial dysfunction. Geroscience. 2018 Jun 18.
    View in: PubMed
    Score: 0.036
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Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.