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This is a "connection" page, showing publications co-authored by Anna Csiszar and Zoltan Ungvari.
Anna Csiszar
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36.225
Zoltan Ungvari
  1. Hypertension-induced cognitive impairment: from pathophysiology to public health. Nat Rev Nephrol. 2021 Oct; 17(10):639-654.
    View in: PubMed
    Score: 0.779
  2. Companion animals likely do not spread COVID-19 but may get infected themselves. Geroscience. 2020 10; 42(5):1229-1236.
    View in: PubMed
    Score: 0.734
  3. Mechanisms of Vascular Aging, A Geroscience Perspective: JACC Focus Seminar. J Am Coll Cardiol. 2020 03 03; 75(8):931-941.
    View in: PubMed
    Score: 0.713
  4. Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases. Geroscience. 2019 12; 41(6):727-738.
    View in: PubMed
    Score: 0.695
  5. Potential Adverse Cardiovascular Effects of Treatment With Fluoxetine and Other Selective Serotonin Reuptake Inhibitors (SSRIs) in Patients With Geriatric Depression: Implications for Atherogenesis and Cerebromicrovascular Dysregulation. Front Genet. 2019; 10:898.
    View in: PubMed
    Score: 0.691
  6. Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research. Geroscience. 2019 04; 41(2):209-227.
    View in: PubMed
    Score: 0.672
  7. Role of endothelial NAD+ deficiency in age-related vascular dysfunction. Am J Physiol Heart Circ Physiol. 2019 06 01; 316(6):H1253-H1266.
    View in: PubMed
    Score: 0.666
  8. Mechanisms of Vascular Aging. Circ Res. 2018 09 14; 123(7):849-867.
    View in: PubMed
    Score: 0.644
  9. Endothelial dysfunction and angiogenesis impairment in the ageing vasculature. Nat Rev Cardiol. 2018 09; 15(9):555-565.
    View in: PubMed
    Score: 0.642
  10. Connective tissue growth factor (CTGF) in age-related vascular pathologies. Geroscience. 2017 12; 39(5-6):491-498.
    View in: PubMed
    Score: 0.600
  11. Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats. Am J Physiol Heart Circ Physiol. 2014 Aug 01; 307(3):H292-306.
    View in: PubMed
    Score: 0.479
  12. Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in ß-amyloid generation and Alzheimer's disease. Am J Physiol Heart Circ Physiol. 2013 Oct 15; 305(8):H1120-30.
    View in: PubMed
    Score: 0.453
  13. Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells. J Gerontol A Biol Sci Med Sci. 2013 Aug; 68(8):877-91.
    View in: PubMed
    Score: 0.432
  14. Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells. J Gerontol A Biol Sci Med Sci. 2013 Mar; 68(3):235-49.
    View in: PubMed
    Score: 0.422
  15. The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances. J Gerontol A Biol Sci Med Sci. 2012 Jun; 67(6):599-610.
    View in: PubMed
    Score: 0.411
  16. Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment. J Gerontol A Biol Sci Med Sci. 2012 Aug; 67(8):811-20.
    View in: PubMed
    Score: 0.405
  17. Testing the oxidative stress hypothesis of aging in primate fibroblasts: is there a correlation between species longevity and cellular ROS production? J Gerontol A Biol Sci Med Sci. 2012 Aug; 67(8):841-52.
    View in: PubMed
    Score: 0.405
  18. Mitochondrial protection by resveratrol. Exerc Sport Sci Rev. 2011 Jul; 39(3):128-32.
    View in: PubMed
    Score: 0.391
  19. Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta. J Gerontol A Biol Sci Med Sci. 2011 Aug; 66(8):866-75.
    View in: PubMed
    Score: 0.388
  20. Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response. Am J Physiol Heart Circ Physiol. 2011 Aug; 301(2):H363-72.
    View in: PubMed
    Score: 0.388
  21. Extreme longevity is associated with increased resistance to oxidative stress in Arctica islandica, the longest-living non-colonial animal. J Gerontol A Biol Sci Med Sci. 2011 Jul; 66(7):741-50.
    View in: PubMed
    Score: 0.385
  22. Resveratrol confers endothelial protection in insulin-dependent diabetes mellitus: editorial to: "Resveratrol shows vasoprotective effect reducing oxidative stress without affecting metabolic disturbances in insulin-dependent diabetes of rabbits" by F. Akar et al. Cardiovasc Drugs Ther. 2011 Apr; 25(2):111-3.
    View in: PubMed
    Score: 0.384
  23. Free radical production, antioxidant capacity, and oxidative stress response signatures in fibroblasts from Lewis dwarf rats: effects of life span-extending peripubertal GH treatment. J Gerontol A Biol Sci Med Sci. 2011 May; 66(5):501-10.
    View in: PubMed
    Score: 0.381
  24. Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia. Am J Physiol Heart Circ Physiol. 2011 Apr; 300(4):H1133-40.
    View in: PubMed
    Score: 0.378
  25. Mitochondria and aging in the vascular system. J Mol Med (Berl). 2010 Oct; 88(10):1021-7.
    View in: PubMed
    Score: 0.368
  26. Vasoprotective effects of life span-extending peripubertal GH replacement in Lewis dwarf rats. J Gerontol A Biol Sci Med Sci. 2010 Nov; 65(11):1145-56.
    View in: PubMed
    Score: 0.368
  27. Mechanisms of vascular aging: new perspectives. J Gerontol A Biol Sci Med Sci. 2010 Oct; 65(10):1028-41.
    View in: PubMed
    Score: 0.364
  28. Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. Am J Physiol Heart Circ Physiol. 2010 Jul; 299(1):H18-24.
    View in: PubMed
    Score: 0.360
  29. Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells. Am J Physiol Heart Circ Physiol. 2009 Nov; 297(5):H1876-81.
    View in: PubMed
    Score: 0.345
  30. Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats. Hypertension. 2009 Sep; 54(3):668-75.
    View in: PubMed
    Score: 0.341
  31. Hemodynamic forces, vascular oxidative stress, and regulation of BMP-2/4 expression. Antioxid Redox Signal. 2009 Jul; 11(7):1683-97.
    View in: PubMed
    Score: 0.340
  32. Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1. Mech Ageing Dev. 2009 Aug; 130(8):518-27.
    View in: PubMed
    Score: 0.339
  33. Resveratrol induces mitochondrial biogenesis in endothelial cells. Am J Physiol Heart Circ Physiol. 2009 Jul; 297(1):H13-20.
    View in: PubMed
    Score: 0.337
  34. Oxidative stress and accelerated vascular aging: implications for cigarette smoking. Front Biosci (Landmark Ed). 2009 01 01; 14(8):3128-44.
    View in: PubMed
    Score: 0.329
  35. Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice. Am J Physiol Heart Circ Physiol. 2008 Nov; 295(5):H1882-94.
    View in: PubMed
    Score: 0.321
  36. Endothelial dysfunction and vascular inflammation in type 2 diabetes: interaction of AGE/RAGE and TNF-alpha signaling. Am J Physiol Heart Circ Physiol. 2008 Aug; 295(2):H475-6.
    View in: PubMed
    Score: 0.317
  37. Inflammation and endothelial dysfunction during aging: role of NF-kappaB. J Appl Physiol (1985). 2008 Oct; 105(4):1333-41.
    View in: PubMed
    Score: 0.317
  38. Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells. Am J Physiol Heart Circ Physiol. 2008 Aug; 295(2):H569-77.
    View in: PubMed
    Score: 0.316
  39. Oxidative stress in vascular senescence: lessons from successfully aging species. Front Biosci. 2008 May 01; 13:5056-70.
    View in: PubMed
    Score: 0.314
  40. Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations. Am J Physiol Heart Circ Physiol. 2008 Jun; 294(6):H2721-35.
    View in: PubMed
    Score: 0.313
  41. Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats. Am J Physiol Heart Circ Physiol. 2008 May; 294(5):H2121-8.
    View in: PubMed
    Score: 0.310
  42. Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity. Aging Cell. 2007 Dec; 6(6):783-97.
    View in: PubMed
    Score: 0.302
  43. Vascular aging in the longest-living rodent, the naked mole rat. Am J Physiol Heart Circ Physiol. 2007 Aug; 293(2):H919-27.
    View in: PubMed
    Score: 0.292
  44. Increased mitochondrial H2O2 production promotes endothelial NF-kappaB activation in aged rat arteries. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H37-47.
    View in: PubMed
    Score: 0.291
  45. The aging kidney: role of endothelial oxidative stress and inflammation. Acta Physiol Hung. 2007 Mar; 94(1-2):107-15.
    View in: PubMed
    Score: 0.289
  46. Downregulation of bone morphogenetic protein 4 expression in coronary arterial endothelial cells: role of shear stress and the cAMP/protein kinase A pathway. Arterioscler Thromb Vasc Biol. 2007 Apr; 27(4):776-82.
    View in: PubMed
    Score: 0.288
  47. Resveratrol increases vascular oxidative stress resistance. Am J Physiol Heart Circ Physiol. 2007 May; 292(5):H2417-24.
    View in: PubMed
    Score: 0.287
  48. Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging. Am J Pathol. 2007 Jan; 170(1):388-98.
    View in: PubMed
    Score: 0.286
  49. Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: role of NF-kappaB inhibition. Am J Physiol Heart Circ Physiol. 2006 Oct; 291(4):H1694-9.
    View in: PubMed
    Score: 0.281
  50. Mechanosensitive production of reactive oxygen species in endothelial and smooth muscle cells: role in microvascular remodeling? Antioxid Redox Signal. 2006 Jul-Aug; 8(7-8):1121-9.
    View in: PubMed
    Score: 0.276
  51. Altered mitochondrial energy metabolism may play a role in vascular aging. Med Hypotheses. 2006; 67(4):904-8.
    View in: PubMed
    Score: 0.275
  52. Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype. Am J Pathol. 2006 Feb; 168(2):629-38.
    View in: PubMed
    Score: 0.268
  53. Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging. Curr Vasc Pharmacol. 2005 Jul; 3(3):285-91.
    View in: PubMed
    Score: 0.258
  54. Regulation of bone morphogenetic protein-2 expression in endothelial cells: role of nuclear factor-kappaB activation by tumor necrosis factor-alpha, H2O2, and high intravascular pressure. Circulation. 2005 May 10; 111(18):2364-72.
    View in: PubMed
    Score: 0.254
  55. Synergistic effects of vascular IL-17 and TNFalpha may promote coronary artery disease. Med Hypotheses. 2004; 63(4):696-8.
    View in: PubMed
    Score: 0.232
  56. The Semmelweis Study: a longitudinal occupational cohort study within the framework of the Semmelweis Caring University Model Program for supporting healthy aging. Geroscience. 2023 Dec 07.
    View in: PubMed
    Score: 0.231
  57. The multifaceted benefits of walking for healthy aging: from Blue Zones to molecular mechanisms. Geroscience. 2023 Jul 26.
    View in: PubMed
    Score: 0.225
  58. Oxidative stress-induced isoprostane formation may contribute to aspirin resistance in platelets. Prostaglandins Leukot Essent Fatty Acids. 2002 May-Jun; 66(5-6):557-8.
    View in: PubMed
    Score: 0.207
  59. Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling. Geroscience. 2022 04; 44(2):953-981.
    View in: PubMed
    Score: 0.204
  60. Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain. Geroscience. 2022 04; 44(2):661-681.
    View in: PubMed
    Score: 0.203
  61. Cerebral venous congestion exacerbates cerebral microhemorrhages in mice. Geroscience. 2022 04; 44(2):805-816.
    View in: PubMed
    Score: 0.202
  62. Can simvastatin promote tumor growth by inducing angiogenesis similar to VEGF? Med Hypotheses. 2002 Jan; 58(1):85-6.
    View in: PubMed
    Score: 0.202
  63. Animal reservoirs of SARS-CoV-2: calculable COVID-19 risk for older adults from animal to human transmission. Geroscience. 2021 10; 43(5):2305-2320.
    View in: PubMed
    Score: 0.198
  64. Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice. Geroscience. 2021 10; 43(5):2427-2440.
    View in: PubMed
    Score: 0.197
  65. Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice. Geroscience. 2021 10; 43(5):2611-2619.
    View in: PubMed
    Score: 0.197
  66. Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype. Geroscience. 2021 10; 43(5):2387-2394.
    View in: PubMed
    Score: 0.197
  67. IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging. Geroscience. 2021 04; 43(2):901-911.
    View in: PubMed
    Score: 0.191
  68. Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by longitudinal intravital two-photon microscopy and optical coherence tomography. Am J Physiol Heart Circ Physiol. 2021 04 01; 320(4):H1370-H1392.
    View in: PubMed
    Score: 0.190
  69. Heterochronic blood exchange attenuates age-related neuroinflammation and confers cognitive benefits: do microvascular protective effects play a role? Geroscience. 2021 02; 43(1):111-113.
    View in: PubMed
    Score: 0.190
  70. Obesity-induced cognitive impairment in older adults: a microvascular perspective. Am J Physiol Heart Circ Physiol. 2021 02 01; 320(2):H740-H761.
    View in: PubMed
    Score: 0.188
  71. Midlife Obesity Impairs Neurovascular Coupling Responses. Obesity (Silver Spring). 2021 01; 29(1):17.
    View in: PubMed
    Score: 0.188
  72. Increases in hypertension-induced cerebral microhemorrhages exacerbate gait dysfunction in a mouse model of Alzheimer's disease. Geroscience. 2020 12; 42(6):1685-1698.
    View in: PubMed
    Score: 0.184
  73. Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain. Geroscience. 2020 04; 42(2):429-444.
    View in: PubMed
    Score: 0.179
  74. Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood. Geroscience. 2020 04; 42(2):727-748.
    View in: PubMed
    Score: 0.179
  75. Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020 04; 42(2):527-546.
    View in: PubMed
    Score: 0.178
  76. Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation-induced impairment of neurovascular coupling responses protecting cognitive function in mice. Geroscience. 2020 04; 42(2):409-428.
    View in: PubMed
    Score: 0.177
  77. Cerebral venous congestion promotes blood-brain barrier disruption and neuroinflammation, impairing cognitive function in mice. Geroscience. 2019 10; 41(5):575-589.
    View in: PubMed
    Score: 0.174
  78. Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging. Geroscience. 2019 10; 41(5):533-542.
    View in: PubMed
    Score: 0.174
  79. Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice. Geroscience. 2019 12; 41(6):711-725.
    View in: PubMed
    Score: 0.174
  80. Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice. Geroscience. 2019 10; 41(5):609-617.
    View in: PubMed
    Score: 0.174
  81. Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects. Geroscience. 2019 08; 41(4):419-439.
    View in: PubMed
    Score: 0.172
  82. Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice: Translational Relevance of Decreased Cadence and Increased Gait Variability. J Gerontol A Biol Sci Med Sci. 2019 08 16; 74(9):1417-1421.
    View in: PubMed
    Score: 0.172
  83. Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment. Geroscience. 2019 10; 41(5):619-630.
    View in: PubMed
    Score: 0.169
  84. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019 06; 24:101192.
    View in: PubMed
    Score: 0.167
  85. IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging. J Gerontol A Biol Sci Med Sci. 2019 03 14; 74(4):446-454.
    View in: PubMed
    Score: 0.167
  86. Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment. Am J Physiol Heart Circ Physiol. 2019 05 01; 316(5):H1124-H1140.
    View in: PubMed
    Score: 0.166
  87. Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline. J Gerontol A Biol Sci Med Sci. 2019 02 15; 74(3):290-298.
    View in: PubMed
    Score: 0.166
  88. Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation. Geroscience. 2018 12; 40(5-6):513-521.
    View in: PubMed
    Score: 0.163
  89. Repeated Valsalva maneuvers promote symptomatic manifestations of cerebral microhemorrhages: implications for the pathogenesis of vascular cognitive impairment in older adults. Geroscience. 2018 12; 40(5-6):485-496.
    View in: PubMed
    Score: 0.162
  90. Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype. J Gerontol A Biol Sci Med Sci. 2018 06 14; 73(7):853-863.
    View in: PubMed
    Score: 0.158
  91. Correction to: Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice. Geroscience. 2018 04; 40(2):219.
    View in: PubMed
    Score: 0.156
  92. Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice. Aging Cell. 2018 04; 17(2).
    View in: PubMed
    Score: 0.154
  93. Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice. Geroscience. 2017 12; 39(5-6):601-614.
    View in: PubMed
    Score: 0.153
  94. Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease. Geroscience. 2017 Aug; 39(4):359-372.
    View in: PubMed
    Score: 0.150
  95. Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment. Geroscience. 2017 Aug; 39(4):385-406.
    View in: PubMed
    Score: 0.148
  96. Cerebral microhemorrhages: mechanisms, consequences, and prevention. Am J Physiol Heart Circ Physiol. 2017 Jun 01; 312(6):H1128-H1143.
    View in: PubMed
    Score: 0.145
  97. Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype. Aging Cell. 2017 06; 16(3):469-479.
    View in: PubMed
    Score: 0.145
  98. The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer. Geroscience. 2017 04; 39(2):147-160.
    View in: PubMed
    Score: 0.144
  99. Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence. Geroscience. 2017 02; 39(1):33-42.
    View in: PubMed
    Score: 0.144
  100. Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline. Exp Gerontol. 2017 08; 94:52-58.
    View in: PubMed
    Score: 0.142
  101. Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging. Am J Physiol Heart Circ Physiol. 2017 Jan 01; 312(1):H1-H20.
    View in: PubMed
    Score: 0.141
  102. Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging. Age (Dordr). 2016 Aug; 38(4):273-289.
    View in: PubMed
    Score: 0.140
  103. IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis. Age (Dordr). 2016 Aug; 38(4):239-258.
    View in: PubMed
    Score: 0.140
  104. Association between gait characteristics and endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease. Age (Dordr). 2016 Jun; 38(3):64.
    View in: PubMed
    Score: 0.137
  105. Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex. Am J Physiol Heart Circ Physiol. 2015 Dec 01; 309(11):H1837-45.
    View in: PubMed
    Score: 0.131
  106. IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging. Aging Cell. 2015 Dec; 14(6):1034-44.
    View in: PubMed
    Score: 0.129
  107. Aging impairs myogenic adaptation to pulsatile pressure in mouse cerebral arteries. J Cereb Blood Flow Metab. 2015 Mar 31; 35(4):527-30.
    View in: PubMed
    Score: 0.127
  108. Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection. Aging Cell. 2015 Jun; 14(3):400-8.
    View in: PubMed
    Score: 0.125
  109. Aging Exacerbates Pressure-Induced Mitochondrial Oxidative Stress in Mouse Cerebral Arteries. J Gerontol A Biol Sci Med Sci. 2015 Nov; 70(11):1355-9.
    View in: PubMed
    Score: 0.125
  110. IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice. J Cereb Blood Flow Metab. 2014 Dec; 34(12):1887-97.
    View in: PubMed
    Score: 0.122
  111. Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells. J Gerontol A Biol Sci Med Sci. 2015 Jun; 70(6):665-74.
    View in: PubMed
    Score: 0.121
  112. Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1339-52.
    View in: PubMed
    Score: 0.120
  113. Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats. J Gerontol A Biol Sci Med Sci. 2015 Mar; 70(3):303-13.
    View in: PubMed
    Score: 0.118
  114. Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase. Am J Physiol Heart Circ Physiol. 2014 Feb; 306(3):H299-308.
    View in: PubMed
    Score: 0.116
  115. Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease. J Gerontol A Biol Sci Med Sci. 2014 Oct; 69(10):1212-26.
    View in: PubMed
    Score: 0.115
  116. Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice. Am J Physiol Heart Circ Physiol. 2013 Dec; 305(12):H1698-708.
    View in: PubMed
    Score: 0.114
  117. Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension. J Cereb Blood Flow Metab. 2013 Nov; 33(11):1732-42.
    View in: PubMed
    Score: 0.113
  118. Insulin-like growth factor-1 in CNS and cerebrovascular aging. Front Aging Neurosci. 2013; 5:27.
    View in: PubMed
    Score: 0.112
  119. Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial cells: role of increased DNA damage and decreased DNA repair capacity in microvascular radiosensitivity. J Gerontol A Biol Sci Med Sci. 2013 Dec; 68(12):1443-57.
    View in: PubMed
    Score: 0.111
  120. Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation. J Gerontol A Biol Sci Med Sci. 2013 Jul; 68(7):780-92.
    View in: PubMed
    Score: 0.108
  121. Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients. J Gerontol A Biol Sci Med Sci. 2013 Jun; 68(6):652-60.
    View in: PubMed
    Score: 0.108
  122. Resistance to genotoxic stresses in Arctica islandica, the longest living noncolonial animal: is extreme longevity associated with a multistress resistance phenotype? J Gerontol A Biol Sci Med Sci. 2013 May; 68(5):521-9.
    View in: PubMed
    Score: 0.107
  123. Testing predictions of the oxidative stress hypothesis of aging using a novel invertebrate model of longevity: the giant clam (Tridacna derasa). J Gerontol A Biol Sci Med Sci. 2013 Apr; 68(4):359-67.
    View in: PubMed
    Score: 0.106
  124. Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies. J Gerontol A Biol Sci Med Sci. 2012 Jun; 67(6):587-98.
    View in: PubMed
    Score: 0.103
  125. Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging. J Gerontol A Biol Sci Med Sci. 2012 Aug; 67(8):821-9.
    View in: PubMed
    Score: 0.101
  126. Growth hormone and IGF-1 deficiency exacerbate high-fat diet-induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging. J Gerontol A Biol Sci Med Sci. 2012 Jun; 67(6):553-64.
    View in: PubMed
    Score: 0.100
  127. Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging. J Gerontol A Biol Sci Med Sci. 2012 Apr; 67(4):313-29.
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  130. Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging. Circ Res. 2008 Mar 14; 102(5):519-28.
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  133. Vascular dysfunction in aging: potential effects of resveratrol, an anti-inflammatory phytoestrogen. Curr Med Chem. 2006; 13(9):989-96.
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  136. Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging. Physiol Genomics. 2004 Mar 12; 17(1):21-30.
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  137. High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase. Circulation. 2003 Sep 09; 108(10):1253-8.
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  138. Aging-induced proinflammatory shift in cytokine expression profile in coronary arteries. FASEB J. 2003 Jun; 17(9):1183-5.
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  141. Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function. Circ Res. 2002 Jun 14; 90(11):1159-66.
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  142. Urinary Biomarkers of Oxidative Stress in Aging: Implications for Prediction of Accelerated Biological Age in Prospective Cohort Studies. Oxid Med Cell Longev. 2022; 2022:6110226.
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  143. Increases in endothelial Ca(2+) activate K(Ca) channels and elicit EDHF-type arteriolar dilation via gap junctions. Am J Physiol Heart Circ Physiol. 2002 May; 282(5):H1760-7.
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  144. Microvascular dysfunction and neurovascular uncoupling are exacerbated in peripheral artery disease, increasing the risk of cognitive decline in older adults. Am J Physiol Heart Circ Physiol. 2022 06 01; 322(6):H924-H935.
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  145. Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging. Front Aging Neurosci. 2022; 14:788296.
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  146. Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses. Sci Rep. 2021 10 25; 11(1):20994.
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  147. Expanding the horizon of research into the pathogenesis of the white matter diseases: Proceedings of the 2021 Annual Workshop of the Albert Research Institute for White Matter and Cognition. Geroscience. 2022 02; 44(1):25-37.
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  148. Cognitive decrement in older adults with symptomatic peripheral artery disease. Geroscience. 2021 10; 43(5):2455-2465.
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  149. Early manifestation of gait alterations in the Tg2576 mouse model of Alzheimer's disease. Geroscience. 2021 08; 43(4):1947-1957.
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  150. Sleep deprivation alters task-related changes in functional connectivity of the frontal cortex: A near-infrared spectroscopy study. Brain Behav. 2021 08; 11(8):e02135.
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  151. Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults. PLoS One. 2021; 16(5):e0250043.
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  152. Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling. Geroscience. 2021 02; 43(1):197-212.
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  153. Retinal biomarkers for Alzheimer's disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis. Geroscience. 2020 12; 42(6):1499-1525.
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  154. CD82-TRPM7-Numb signaling mediates age-related cognitive impairment. Geroscience. 2020 04; 42(2):595-611.
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  155. Microvascular contributions to age-related macular degeneration (AMD): from mechanisms of choriocapillaris aging to novel interventions. Geroscience. 2019 12; 41(6):813-845.
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  156. Assessment of age-related decline of neurovascular coupling responses by functional near-infrared spectroscopy (fNIRS) in humans. Geroscience. 2019 10; 41(5):495-509.
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  157. Age-related impairment of neurovascular coupling responses: a dynamic vessel analysis (DVA)-based approach to measure decreased flicker light stimulus-induced retinal arteriolar dilation in healthy older adults. Geroscience. 2019 06; 41(3):341-349.
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  158. Age-related decline in peripheral vascular health predicts cognitive impairment. Geroscience. 2019 04; 41(2):125-136.
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  159. Advances and challenges in geroscience research: An update. Physiol Int. 2018 Dec 01; 105(4):298-308.
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  160. Age-related focal loss of contractile vascular smooth muscle cells in retinal arterioles is accelerated by caveolin-1 deficiency. Neurobiol Aging. 2018 11; 71:1-12.
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  161. Short-term weight loss reverses obesity-induced microvascular endothelial dysfunction. Geroscience. 2018 Jun 18.
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  162. Simultaneous assessment of cognitive function, circadian rhythm, and spontaneous activity in aging mice. Geroscience. 2018 04; 40(2):123-137.
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  163. Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass. Redox Biol. 2018 07; 17:47-58.
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  164. Endothelial Cell Inflammation and Antioxidant Capacity are Associated With 6-Minute Walk Performance in Patients With Symptomatic Peripheral Artery Disease. Angiology. 2018 May; 69(5):416-423.
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  165. Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer's disease using functional laser speckle contrast imaging. Geroscience. 2017 Aug; 39(4):465-473.
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  166. IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan. Geroscience. 2017 04; 39(2):129-145.
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  167. Association between daily walking and antioxidant capacity in patients with symptomatic peripheral artery disease. J Vasc Surg. 2017 06; 65(6):1762-1768.
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  168. Pharmacological Strategies to Retard Cardiovascular Aging. Circ Res. 2016 05 13; 118(10):1626-42.
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  169. Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet. Aging (Albany NY). 2016 05; 8(5):899-916.
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  170. INFLUENCE OF DIABETES ON AMBULATION AND INFLAMMATION IN MEN AND WOMEN WITH SYMPTOMATIC PERIPHERAL ARTERY DISEASE. J Clin Transl Endocrinol. 2015 Dec 01; 2(4):137-143.
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  171. Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment. J Gerontol A Biol Sci Med Sci. 2016 Jan; 71(1):13-20.
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  172. Biotin-conjugated fusogenic liposomes for high-quality cell purification. J Biomater Appl. 2016 Jan; 30(6):846-56.
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  173. IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms. J Bone Miner Res. 2016 Feb; 31(2):443-54.
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  174. Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice. J Cereb Blood Flow Metab. 2015 Nov; 35(11):1871-81.
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  175. Endothelial Cell Inflammation and Antioxidant Capacity are Associated With Exercise Performance and Microcirculation in Patients With Symptomatic Peripheral Artery Disease. Angiology. 2015 Oct; 66(9):867-74.
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  176. Endothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1353-62.
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  177. Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells. Am J Physiol Heart Circ Physiol. 2014 Sep 15; 307(6):H858-68.
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  179. Greater endothelial apoptosis and oxidative stress in patients with peripheral artery disease. Int J Vasc Med. 2014; 2014:160534.
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  181. A heart that beats for 500 years: age-related changes in cardiac proteasome activity, oxidative protein damage and expression of heat shock proteins, inflammatory factors, and mitochondrial complexes in Arctica islandica, the longest-living noncolonial animal. J Gerontol A Biol Sci Med Sci. 2014 Dec; 69(12):1448-61.
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  182. Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications. J Vasc Res. 2013; 50(6):445-57.
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  184. Treatment with the cytochrome P450 ?-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats. Br J Pharmacol. 2013 Apr; 168(8):1878-88.
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  185. SRT1720 improves survival and healthspan of obese mice. Sci Rep. 2011; 1:70.
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  186. Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression. Neuroscience. 2011 Jun 30; 185:50-60.
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  187. Role of NAD(P)H oxidase in superoxide generation and endothelial dysfunction in Goto-Kakizaki (GK) rats as a model of nonobese NIDDM. PLoS One. 2010 Jul 26; 5(7):e11800.
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  188. Effect of prenatal glucocorticoids on cerebral vasculature of the developing brain. Stroke. 2010 Aug; 41(8):1766-73.
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  189. Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition. Brain. 2010 Aug; 133(Pt 8):2264-80.
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  190. Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy. Circ Res. 2010 Jun 25; 106(12):1893-903.
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  191. Effect of hyperoxic resuscitation on propensity of germinal matrix haemorrhage and cerebral injury. Neuropathol Appl Neurobiol. 2010 Aug; 36(5):448-58.
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  192. Caveolin-1 limits the contribution of BK(Ca) channel to EDHF-mediated arteriolar dilation: implications in diet-induced obesity. Cardiovasc Res. 2010 Sep 01; 87(4):732-9.
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  194. The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. Am J Pathol. 2009 Jan; 174(1):34-43.
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  195. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab. 2008 Aug; 8(2):157-68.
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  196. Maturational changes in laminin, fibronectin, collagen IV, and perlecan in germinal matrix, cortex, and white matter and effect of betamethasone. J Neurosci Res. 2008 May 15; 86(7):1482-500.
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  197. Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2325-30.
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  198. Paucity of pericytes in germinal matrix vasculature of premature infants. J Neurosci. 2007 Oct 31; 27(44):12012-24.
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  199. CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion. Am J Physiol Heart Circ Physiol. 2007 Oct; 293(4):H2210-8.
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  200. Inhibition of NAD(P)H oxidase attenuates aggregation of platelets from high-risk cardiac patients with aspirin resistance. Pharmacol Rep. 2007 Jul-Aug; 59(4):428-36.
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  201. Angiogenic inhibition reduces germinal matrix hemorrhage. Nat Med. 2007 Apr; 13(4):477-85.
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  203. Different roles of PKC and MAP kinases in arteriolar constrictions to pressure and agonists. Am J Physiol Heart Circ Physiol. 2002 Dec; 283(6):H2282-7.
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