Paul Cook to Models, Molecular
This is a "connection" page, showing publications Paul Cook has written about Models, Molecular.
Connection Strength
1.803
-
A three-dimensional homology model of the O-acetylserine sulfhydrylase-B from Salmonella typhimurium. Protein Pept Lett. 2006; 13(1):7-13.
Score: 0.232
-
Supporting role of lysine 13 and glutamate 16 in the acid-base mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae. Arch Biochem Biophys. 2012 Jun 01; 522(1):57-61.
Score: 0.090
-
The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH. Arch Biochem Biophys. 2011 Sep 15; 513(2):71-80.
Score: 0.085
-
Contribution of K99 and D319 to substrate binding and catalysis in the saccharopine dehydrogenase reaction. Arch Biochem Biophys. 2011 Oct; 514(1-2):8-15.
Score: 0.085
-
The multifaceted pyridoxal 5'-phosphate-dependent O-acetylserine sulfhydrylase. Biochim Biophys Acta. 2011 Nov; 1814(11):1497-510.
Score: 0.084
-
Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts. J Biol Chem. 2010 Jul 02; 285(27):20756-68.
Score: 0.078
-
(31)P NMR studies of O-acetylserine sulfhydrylase-B from Salmonella typhimurium. Arch Biochem Biophys. 2009 Jul 15; 487(2):85-90.
Score: 0.073
-
A lysine-tyrosine pair carries out acid-base chemistry in the metal ion-dependent pyridine dinucleotide-linked beta-hydroxyacid oxidative decarboxylases. Biochemistry. 2009 Apr 28; 48(16):3565-77.
Score: 0.073
-
Evidence for a catalytic dyad in the active site of homocitrate synthase from Saccharomyces cerevisiae. Biochemistry. 2008 Jul 01; 47(26):6851-8.
Score: 0.069
-
Examination of intrinsic sulfonamide resistance in Bacillus anthracis: a novel assay for dihydropteroate synthase. Biochim Biophys Acta. 2008 May; 1780(5):848-53.
Score: 0.067
-
Proper positioning of the nicotinamide ring is crucial for the Ascaris suum malic enzyme reaction. Biochemistry. 2008 Feb 26; 47(8):2539-46.
Score: 0.067
-
Proper orientation of the nicotinamide ring of NADP is important for the precatalytic conformational change in the 6-phosphogluconate dehydrogenase reaction. Biochemistry. 2008 Feb 19; 47(7):1862-70.
Score: 0.067
-
Structure, mechanism, and conformational dynamics of O-acetylserine sulfhydrylase from Salmonella typhimurium: comparison of A and B isozymes. Biochemistry. 2007 Jul 17; 46(28):8315-30.
Score: 0.064
-
Role of the S128, H186, and N187 triad in substrate binding and decarboxylation in the sheep liver 6-phosphogluconate dehydrogenase reaction. Biochemistry. 2006 Oct 24; 45(42):12680-6.
Score: 0.061
-
The 2'-phosphate of NADP is responsible for proper orientation of the nicotinamide ring in the oxidative decarboxylation reaction catalyzed by sheep liver 6-phosphogluconate dehydrogenase. J Biol Chem. 2006 Dec 01; 281(48):36803-10.
Score: 0.061
-
Importance in catalysis of the 6-phosphate-binding site of 6-phosphogluconate in sheep liver 6-phosphogluconate dehydrogenase. J Biol Chem. 2006 Sep 01; 281(35):25568-76.
Score: 0.060
-
Crystal structure of the his-tagged saccharopine reductase from Saccharomyces cerevisiae at 1.7-A resolution. Cell Biochem Biophys. 2006; 46(1):17-26.
Score: 0.058
-
The serine acetyltransferase reaction: acetyl transfer from an acylpantothenyl donor to an alcohol. Arch Biochem Biophys. 2005 Jan 01; 433(1):85-95.
Score: 0.054
-
Structure and mechanism of O-acetylserine sulfhydrylase. J Biol Chem. 2004 Jun 25; 279(26):26803-6.
Score: 0.051
-
Pyridoxal 5'-phosphate-dependent alpha,beta-elimination reactions: mechanism of O-acetylserine sulfhydrylase. Acc Chem Res. 2001 Jan; 34(1):49-59.
Score: 0.041
-
Identification of an allosteric anion-binding site on O-acetylserine sulfhydrylase: structure of the enzyme with chloride bound. J Mol Biol. 2000 Oct 20; 303(2):279-86.
Score: 0.040
-
O-acetylserine sulfhydrylase. Adv Enzymol Relat Areas Mol Biol. 2000; 74:185-234.
Score: 0.038
-
Cysteine 42 is important for maintaining an integral active site for O-acetylserine sulfhydrylase resulting in the stabilization of the alpha-aminoacrylate intermediate. Biochemistry. 1998 Jul 28; 37(30):10597-604.
Score: 0.035
-
Three-dimensional structure of O-acetylserine sulfhydrylase from Salmonella typhimurium. J Mol Biol. 1998; 283(1):121-33.
Score: 0.033
-
Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2012 Jan 31; 51(4):857-66.
Score: 0.022
-
Exploring O-acetylserine sulfhydrylase-B isoenzyme from Salmonella typhimurium by fluorescence spectroscopy. Arch Biochem Biophys. 2011 Jan 15; 505(2):178-85.
Score: 0.020
-
Design of O-acetylserine sulfhydrylase inhibitors by mimicking nature. J Med Chem. 2010 Jan 14; 53(1):345-56.
Score: 0.019
-
Crystal structures of ligand-bound saccharopine dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2007 Nov 06; 46(44):12512-21.
Score: 0.016
-
Kinetic analysis of YPD1-dependent phosphotransfer reactions in the yeast osmoregulatory phosphorelay system. Biochemistry. 2005 Jan 11; 44(1):377-86.
Score: 0.014
-
Crystal structure of the malic enzyme from Ascaris suum complexed with nicotinamide adenine dinucleotide at 2.3 A resolution. Biochemistry. 2002 Jun 04; 41(22):6928-38.
Score: 0.011
-
Ligand binding induces a large conformational change in O-acetylserine sulfhydrylase from Salmonella typhimurium. J Mol Biol. 1999 Aug 27; 291(4):941-53.
Score: 0.009
-
Crystal structure of the H256A mutant of rat testis fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase. Fructose 6-phosphate in the active site leads to mechanisms for both mutant and wild type bisphosphatase activities. J Biol Chem. 1999 Jan 22; 274(4):2176-84.
Score: 0.009
-
Chemical mechanism of the fructose-6-phosphate,2-kinase reaction from the pH dependence of kinetic parameters of site-directed mutants of active site basic residues. Biochemistry. 1997 Jul 22; 36(29):8775-84.
Score: 0.008
-
Comparison of the substrate specificities of cAMP-dependent protein kinase from bovine heart and Ascaris suum muscle. Biol Chem Hoppe Seyler. 1996 Mar; 377(3):203-9.
Score: 0.007