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Paul Cook to Saccharomyces cerevisiae

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This is a "connection" page, showing publications Paul Cook has written about Saccharomyces cerevisiae.
Paul Cook
Connection Strength
5.811
Saccharomyces cerevisiae
  1. Probing the chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae using site-directed mutagenesis. Arch Biochem Biophys. 2015 Oct 15; 584:98-106.
    View in: PubMed
    Score: 0.442
  2. Evidence for an induced conformational change in the catalytic mechanism of homoisocitrate dehydrogenase for Saccharomyces cerevisiae: Characterization of the D271N mutant enzyme. Arch Biochem Biophys. 2015 Oct 15; 584:20-7.
    View in: PubMed
    Score: 0.441
  3. Supporting role of lysine 13 and glutamate 16 in the acid-base mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae. Arch Biochem Biophys. 2012 Jun 01; 522(1):57-61.
    View in: PubMed
    Score: 0.349
  4. Contribution of K99 and D319 to substrate binding and catalysis in the saccharopine dehydrogenase reaction. Arch Biochem Biophys. 2011 Oct; 514(1-2):8-15.
    View in: PubMed
    Score: 0.332
  5. Site-directed mutagenesis as a probe of the acid-base catalytic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2009 Aug 04; 48(30):7305-12.
    View in: PubMed
    Score: 0.290
  6. Chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae. Biochemistry. 2009 Jun 30; 48(25):5899-907.
    View in: PubMed
    Score: 0.288
  7. Potassium is an activator of homoisocitrate dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2008 Oct 07; 47(40):10809-15.
    View in: PubMed
    Score: 0.272
  8. Evidence for a catalytic dyad in the active site of homocitrate synthase from Saccharomyces cerevisiae. Biochemistry. 2008 Jul 01; 47(26):6851-8.
    View in: PubMed
    Score: 0.267
  9. Overall kinetic mechanism of saccharopine dehydrogenase (L-glutamate forming) from Saccharomyces cerevisiae. Biochemistry. 2008 May 13; 47(19):5417-23.
    View in: PubMed
    Score: 0.265
  10. Chemical mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2008 Apr 01; 47(13):4169-80.
    View in: PubMed
    Score: 0.263
  11. Determinants of substrate specificity for saccharopine dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2007 Jun 26; 46(25):7625-36.
    View in: PubMed
    Score: 0.249
  12. A proposed proton shuttle mechanism for saccharopine dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2007 Jan 23; 46(3):871-82.
    View in: PubMed
    Score: 0.243
  13. Complete kinetic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2007 Jan 23; 46(3):890-8.
    View in: PubMed
    Score: 0.243
  14. Acid-base chemical mechanism of homocitrate synthase from Saccharomyces cerevisiae. Biochemistry. 2006 Oct 03; 45(39):12136-43.
    View in: PubMed
    Score: 0.238
  15. Overall kinetic mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2006 Oct 03; 45(39):12156-66.
    View in: PubMed
    Score: 0.238
  16. Regulatory mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. II. Theory. J Biol Chem. 2005 Sep 09; 280(36):31633-40.
    View in: PubMed
    Score: 0.216
  17. Regulatory mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. I. Kinetic studies. J Biol Chem. 2005 Sep 09; 280(36):31624-32.
    View in: PubMed
    Score: 0.216
  18. Kinetic mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. Biochemistry. 2004 Sep 21; 43(37):11790-5.
    View in: PubMed
    Score: 0.207
  19. Stabilization and characterization of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. Arch Biochem Biophys. 2004 Jan 15; 421(2):243-54.
    View in: PubMed
    Score: 0.197
  20. Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2012 Jan 31; 51(4):857-66.
    View in: PubMed
    Score: 0.086
  21. Mechanism of the aromatic aminotransferase encoded by the Aro8 gene from Saccharomyces cerevisiae. Arch Biochem Biophys. 2011 Dec 01; 516(1):67-74.
    View in: PubMed
    Score: 0.084
  22. The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH. Arch Biochem Biophys. 2011 Sep 15; 513(2):71-80.
    View in: PubMed
    Score: 0.083
  23. Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts. J Biol Chem. 2010 Jul 02; 285(27):20756-68.
    View in: PubMed
    Score: 0.076
  24. Kinetic studies of the yeast His-Asp phosphorelay signaling pathway. Methods Enzymol. 2010; 471:59-75.
    View in: PubMed
    Score: 0.075
  25. Crystal structures of ligand-bound saccharopine dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2007 Nov 06; 46(44):12512-21.
    View in: PubMed
    Score: 0.064
  26. Product dependence of deuterium isotope effects in enzyme-catalyzed reactions. Biochemistry. 1993 Feb 23; 32(7):1795-802.
    View in: PubMed
    Score: 0.023
  27. Effects of osmolytes on the SLN1-YPD1-SSK1 phosphorelay system from Saccharomyces cerevisiae. Biochemistry. 2009 Aug 25; 48(33):8044-50.
    View in: PubMed
    Score: 0.018
  28. Kinetic analysis of YPD1-dependent phosphotransfer reactions in the yeast osmoregulatory phosphorelay system. Biochemistry. 2005 Jan 11; 44(1):377-86.
    View in: PubMed
    Score: 0.013
  29. Solvent isotope effects on the reaction catalyzed by yeast hexokinase. Eur J Biochem. 1983 Aug 15; 134(3):571-4.
    View in: PubMed
    Score: 0.012
  30. pH variation of isotope effects in enzyme-catalyzed reactions. 1. Isotope- and pH-dependent steps the same. Biochemistry. 1981 Mar 31; 20(7):1797-805.
    View in: PubMed
    Score: 0.010
  31. pH variation of isotope effects in enzyme-catalyzed reactions. 2. Isotope-dependent step not pH dependent. Kinetic mechanism of alcohol dehydrogenase. Biochemistry. 1981 Mar 31; 20(7):1805-16.
    View in: PubMed
    Score: 0.010
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.