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Connection

Paul Cook to Malate Dehydrogenase

This is a "connection" page, showing publications Paul Cook has written about Malate Dehydrogenase.
Connection Strength

3.904
  1. Role of residues in the adenosine binding site of NAD of the Ascaris suum malic enzyme. Biochim Biophys Acta. 2008 Dec; 1784(12):2059-64.
    View in: PubMed
    Score: 0.309
  2. Proper positioning of the nicotinamide ring is crucial for the Ascaris suum malic enzyme reaction. Biochemistry. 2008 Feb 26; 47(8):2539-46.
    View in: PubMed
    Score: 0.298
  3. Multiple roles of arginine 181 in binding and catalysis in the NAD-malic enzyme from Ascaris suum. Biochemistry. 2007 Dec 18; 46(50):14578-88.
    View in: PubMed
    Score: 0.295
  4. A catalytic triad is responsible for acid-base chemistry in the Ascaris suum NAD-malic enzyme. Biochemistry. 2005 Mar 08; 44(9):3626-35.
    View in: PubMed
    Score: 0.244
  5. Ascaris suum NAD-malic enzyme is activated by L-malate and fumarate binding to separate allosteric sites. Biochemistry. 2003 Aug 19; 42(32):9712-21.
    View in: PubMed
    Score: 0.219
  6. Alternative substrates for malic enzyme: oxidative decarboxylation of L-aspartate. Biochemistry. 2002 Oct 08; 41(40):12200-3.
    View in: PubMed
    Score: 0.207
  7. Lysine 199 is the general acid in the NAD-malic enzyme reaction. Biochemistry. 2000 Oct 03; 39(39):11955-60.
    View in: PubMed
    Score: 0.180
  8. Mapping the active site topography of the NAD-malic enzyme via alanine-scanning site-directed mutagenesis. Biochemistry. 1999 Aug 10; 38(32):10527-32.
    View in: PubMed
    Score: 0.166
  9. Alpha-secondary tritium kinetic isotope effects indicate hydrogen tunneling and coupled motion occur in the oxidation of L-malate by NAD-malic enzyme. Biochemistry. 1999 Apr 06; 38(14):4398-402.
    View in: PubMed
    Score: 0.162
  10. Expression, purification, and characterization of the recombinant NAD-malic enzyme from Ascaris suum. Protein Expr Purif. 1997 Jun; 10(1):51-4.
    View in: PubMed
    Score: 0.143
  11. Role of the divalent metal ion in the NAD:malic enzyme reaction: an ESEEM determination of the ground state conformation of malate in the E:Mn:malate complex. Protein Sci. 1996 Aug; 5(8):1648-54.
    View in: PubMed
    Score: 0.135
  12. Metal ion activator effects on intrinsic isotope effects for hydride transfer from decarboxylation in the reaction catalyzed by the NAD-malic enzyme from Ascaris suum. Biochemistry. 1995 Mar 14; 34(10):3253-60.
    View in: PubMed
    Score: 0.122
  13. Stepwise versus concerted oxidative decarboxylation catalyzed by malic enzyme: a reinvestigation. Biochemistry. 1994 Mar 01; 33(8):2096-103.
    View in: PubMed
    Score: 0.114
  14. Pre-steady-state kinetics reveal a slow isomerization of the enzyme-NAD complex in the NAD-malic enzyme reaction. Biochemistry. 1993 Mar 02; 32(8):1928-34.
    View in: PubMed
    Score: 0.106
  15. Mechanism of activation of the NAD-malic enzyme from Ascaris suum by fumarate. Arch Biochem Biophys. 1992 Dec; 299(2):214-9.
    View in: PubMed
    Score: 0.104
  16. Multiple isotope effects with alternative dinucleotide substrates as a probe of the malic enzyme reaction. Biochemistry. 1991 Jun 11; 30(23):5755-63.
    View in: PubMed
    Score: 0.094
  17. Modification of a thiol at the active site of the Ascaris suum NAD-malic enzyme results in changes in the rate-determining steps for oxidative decarboxylation of L-malate. Biochemistry. 1991 Jun 11; 30(23):5764-9.
    View in: PubMed
    Score: 0.094
  18. Kinetic mechanism of NAD:malic enzyme from Ascaris suum in the direction of reductive carboxylation. J Biol Chem. 1991 Feb 15; 266(5):2732-8.
    View in: PubMed
    Score: 0.092
  19. Substrate activation by malate induced by oxalate in the Ascaris suum NAD-malic enzyme reaction. Biochemistry. 1989 Jul 25; 28(15):6334-40.
    View in: PubMed
    Score: 0.083
  20. Isotope partitioning for NAD-malic enzyme from Ascaris suum confirms a steady-state random kinetic mechanism. Biochemistry. 1988 Jan 12; 27(1):212-9.
    View in: PubMed
    Score: 0.074
  21. Modification of an arginine residue essential for the activity of NAD-malic enzyme from Ascaris suum. Arch Biochem Biophys. 1987 May 15; 255(1):8-13.
    View in: PubMed
    Score: 0.071
  22. pH dependence of kinetic parameters for oxalacetate decarboxylation and pyruvate reduction reactions catalyzed by malic enzyme. Biochemistry. 1986 Jul 01; 25(13):3752-9.
    View in: PubMed
    Score: 0.067
  23. Protonation mechanism and location of rate-determining steps for the Ascaris suum nicotinamide adenine dinucleotide-malic enzyme reaction from isotope effects and pH studies. Biochemistry. 1986 Jan 14; 25(1):227-36.
    View in: PubMed
    Score: 0.065
  24. Diethylpyrocarbonate inactivation of NAD-malic enzyme from Ascaris suum. Arch Biochem Biophys. 1985 Aug 15; 241(1):67-74.
    View in: PubMed
    Score: 0.063
  25. The pH dependence of the reductive carboxylation of pyruvate by malic enzyme. Biochim Biophys Acta. 1985 Jun 10; 829(2):295-8.
    View in: PubMed
    Score: 0.062
  26. Kinetic mechanism in the direction of oxidative decarboxylation for NAD-malic enzyme from Ascaris suum. Biochemistry. 1984 Nov 06; 23(23):5446-53.
    View in: PubMed
    Score: 0.060
  27. Determination of dissociation constants for enzyme-reactant complexes for NAD-malic enzyme by modulation of the thiol inactivation rate. Biochemistry. 1984 Nov 06; 23(23):5454-9.
    View in: PubMed
    Score: 0.060
  28. Crystallographic studies on Ascaris suum NAD-malic enzyme bound to reduced cofactor and identification of an effector site. J Biol Chem. 2003 Sep 26; 278(39):38051-8.
    View in: PubMed
    Score: 0.054
  29. Crystal structure of the malic enzyme from Ascaris suum complexed with nicotinamide adenine dinucleotide at 2.3 A resolution. Biochemistry. 2002 Jun 04; 41(22):6928-38.
    View in: PubMed
    Score: 0.050
  30. Mechanism from isotope effects. Isotopes Environ Health Stud. 1998; 34(1-2):3-17.
    View in: PubMed
    Score: 0.037
  31. Cloning and nucleotide sequence of a full-length cDNA encoding Ascaris suum malic enzyme. Arch Biochem Biophys. 1993 Jan; 300(1):231-7.
    View in: PubMed
    Score: 0.026
  32. Crystallization of the NAD-dependent malic enzyme from the parasitic nematode Ascaris suum. J Mol Biol. 1992 Jul 20; 226(2):565-9.
    View in: PubMed
    Score: 0.025
  33. pH variation of isotope effects in enzyme-catalyzed reactions. 1. Isotope- and pH-dependent steps the same. Biochemistry. 1981 Mar 31; 20(7):1797-805.
    View in: PubMed
    Score: 0.012
  34. Primary and secondary deuterium isotope effects on equilibrium constants for enzyme-catalyzed reactions. Biochemistry. 1980 Oct 14; 19(21):4853-8.
    View in: PubMed
    Score: 0.011
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.