Robert Matts to Lactams, Macrocyclic
This is a "connection" page, showing publications Robert Matts has written about Lactams, Macrocyclic.
Connection Strength
0.709
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Gambogic acid, a natural product inhibitor of Hsp90. J Nat Prod. 2011 May 27; 74(5):1085-92.
Score: 0.095
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A systematic protocol for the characterization of Hsp90 modulators. Bioorg Med Chem. 2011 Jan 01; 19(1):684-92.
Score: 0.092
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Hsp90 functions to balance the phosphorylation state of Akt during C2C12 myoblast differentiation. Cell Signal. 2005 Dec; 17(12):1477-85.
Score: 0.065
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Cdk2: a genuine protein kinase client of Hsp90 and Cdc37. Biochemistry. 2005 Nov 22; 44(46):15287-95.
Score: 0.065
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Differential effects of Hsp90 inhibition on protein kinases regulating signal transduction pathways required for myoblast differentiation. Exp Cell Res. 2005 Jul 01; 307(1):212-23.
Score: 0.062
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Novobiocin induces a distinct conformation of Hsp90 and alters Hsp90-cochaperone-client interactions. Biochemistry. 2004 Jun 29; 43(25):8217-29.
Score: 0.059
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Evidence that protein phosphatase 5 functions to negatively modulate the maturation of the Hsp90-dependent heme-regulated eIF2alpha kinase. Biochemistry. 2002 May 28; 41(21):6770-9.
Score: 0.051
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Hsp90 regulates p50(cdc37) function during the biogenesis of the activeconformation of the heme-regulated eIF2 alpha kinase. J Biol Chem. 2001 Jan 05; 276(1):206-14.
Score: 0.047
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Molybdate inhibits hsp90, induces structural changes in its C-terminal domain, and alters its interactions with substrates. Biochemistry. 1999 Mar 23; 38(12):3837-49.
Score: 0.041
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Hsp90 is obligatory for the heme-regulated eIF-2alpha kinase to acquire and maintain an activable conformation. J Biol Chem. 1997 Apr 25; 272(17):11648-56.
Score: 0.036
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Effect of geldanamycin on the kinetics of chaperone-mediated renaturation of firefly luciferase in rabbit reticulocyte lysate. Biochemistry. 1996 Oct 15; 35(41):13443-50.
Score: 0.035
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The anticancer drug AUY922 generates a proteomics fingerprint that is highly conserved among structurally diverse Hsp90 inhibitors. J Proteome Res. 2013 Aug 02; 12(8):3697-706.
Score: 0.028
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The molecular chaperone Hsp90 is required for signal transduction by wild-type Hck and maintenance of its constitutively active counterpart. Cell Growth Differ. 2001 Aug; 12(8):409-17.
Score: 0.012
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Effects of geldanamycin, a heat-shock protein 90-binding agent, on T cell function and T cell nonreceptor protein tyrosine kinases. J Immunol. 2000 Mar 15; 164(6):2915-23.
Score: 0.011
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Disruption of zebrafish somite development by pharmacologic inhibition of Hsp90. Dev Biol. 1999 Jun 01; 210(1):56-70.
Score: 0.010