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Connection

Robert Matts to Humans

This is a "connection" page, showing publications Robert Matts has written about Humans.
Connection Strength

0.398
  1. A High-Throughput Screen for Inhibitors of the Hsp90-Chaperone Machine. Methods Mol Biol. 2018; 1709:87-96.
    View in: PubMed
    Score: 0.034
  2. Identification of proteins associated with Aha1 in HeLa cells by quantitative proteomics. Biochim Biophys Acta. 2015 May; 1854(5):365-80.
    View in: PubMed
    Score: 0.028
  3. Hsp90-dependent assembly of the DBC2/RhoBTB2-Cullin3 E3-ligase complex. PLoS One. 2014; 9(3):e90054.
    View in: PubMed
    Score: 0.026
  4. Characterization of the interaction of Aha1 with components of the Hsp90 chaperone machine and client proteins. Biochim Biophys Acta. 2012 Jun; 1823(6):1092-101.
    View in: PubMed
    Score: 0.023
  5. Approaches for defining the Hsp90-dependent proteome. Biochim Biophys Acta. 2012 Mar; 1823(3):656-67.
    View in: PubMed
    Score: 0.022
  6. Elucidation of the Hsp90 C-terminal inhibitor binding site. ACS Chem Biol. 2011 Aug 19; 6(8):800-7.
    View in: PubMed
    Score: 0.022
  7. A systematic protocol for the characterization of Hsp90 modulators. Bioorg Med Chem. 2011 Jan 01; 19(1):684-92.
    View in: PubMed
    Score: 0.021
  8. Assays for identification of Hsp90 inhibitors and biochemical methods for discriminating their mechanism of action. Curr Top Med Chem. 2009; 9(15):1462-78.
    View in: PubMed
    Score: 0.018
  9. High-throughput assay for the identification of Hsp90 inhibitors based on Hsp90-dependent refolding of firefly luciferase. Bioorg Med Chem. 2007 Mar 01; 15(5):1939-46.
    View in: PubMed
    Score: 0.016
  10. Cdk2: a genuine protein kinase client of Hsp90 and Cdc37. Biochemistry. 2005 Nov 22; 44(46):15287-95.
    View in: PubMed
    Score: 0.015
  11. Novobiocin induces a distinct conformation of Hsp90 and alters Hsp90-cochaperone-client interactions. Biochemistry. 2004 Jun 29; 43(25):8217-29.
    View in: PubMed
    Score: 0.013
  12. Phosphorylation of serine 13 is required for the proper function of the Hsp90 co-chaperone, Cdc37. J Biol Chem. 2003 Oct 03; 278(40):38117-20.
    View in: PubMed
    Score: 0.013
  13. Crystal structure of the middle and C-terminal domains of Hsp90a labeled with a coumarin derivative reveals a potential allosteric binding site as a drug target. Acta Crystallogr D Struct Biol. 2022 May 01; 78(Pt 5):571-585.
    View in: PubMed
    Score: 0.011
  14. Selective Inhibition of the Hsp90a Isoform. Angew Chem Int Ed Engl. 2021 05 03; 60(19):10547-10551.
    View in: PubMed
    Score: 0.011
  15. The heme-regulated eukaryotic initiation factor 2alpha kinase. A potential regulatory target for control of protein synthesis by diffusible gases. J Biol Chem. 2001 May 04; 276(18):14875-83.
    View in: PubMed
    Score: 0.011
  16. Hsp90 regulates p50(cdc37) function during the biogenesis of the activeconformation of the heme-regulated eIF2 alpha kinase. J Biol Chem. 2001 Jan 05; 276(1):206-14.
    View in: PubMed
    Score: 0.011
  17. p50(Cdc37) can buffer the temperature-sensitive properties of a mutant of Hck. Mol Cell Biol. 2000 Sep; 20(18):6984-95.
    View in: PubMed
    Score: 0.010
  18. High Throughput Screening for Natural Host Defense Peptide-Inducing Compounds as Novel Alternatives to Antibiotics. Front Cell Infect Microbiol. 2018; 8:191.
    View in: PubMed
    Score: 0.009
  19. Structure-guided design of an Hsp90ß N-terminal isoform-selective inhibitor. Nat Commun. 2018 01 30; 9(1):425.
    View in: PubMed
    Score: 0.009
  20. Proteomic Profiling of Hsp90 Inhibitors. Methods Mol Biol. 2018; 1709:139-162.
    View in: PubMed
    Score: 0.009
  21. Cloning and characterization of cDNAs encoding the epsilon-subunit of eukaryotic initiation factor-2B from rabbit and human. Biochim Biophys Acta. 1996 Jul 17; 1307(3):309-17.
    View in: PubMed
    Score: 0.008
  22. Development of a high-throughput screening cancer cell-based luciferase refolding assay for identifying Hsp90 inhibitors. Assay Drug Dev Technol. 2013 Oct; 11(8):478-88.
    View in: PubMed
    Score: 0.006
  23. The anticancer drug AUY922 generates a proteomics fingerprint that is highly conserved among structurally diverse Hsp90 inhibitors. J Proteome Res. 2013 Aug 02; 12(8):3697-706.
    View in: PubMed
    Score: 0.006
  24. Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine. Mol Cell. 2012 Aug 10; 47(3):434-43.
    View in: PubMed
    Score: 0.006
  25. Development and characterization of a novel C-terminal inhibitor of Hsp90 in androgen dependent and independent prostate cancer cells. BMC Cancer. 2011 Oct 31; 11:468.
    View in: PubMed
    Score: 0.006
  26. Identification and initial SAR of silybin: an Hsp90 inhibitor. Bioorg Med Chem Lett. 2011 May 01; 21(9):2659-64.
    View in: PubMed
    Score: 0.005
  27. Characterization of a novel novobiocin analogue as a putative C-terminal inhibitor of heat shock protein 90 in prostate cancer cells. Prostate. 2010 Jan 01; 70(1):27-36.
    View in: PubMed
    Score: 0.005
  28. KU135, a novel novobiocin-derived C-terminal inhibitor of the 90-kDa heat shock protein, exerts potent antiproliferative effects in human leukemic cells. Mol Pharmacol. 2009 Dec; 76(6):1314-22.
    View in: PubMed
    Score: 0.005
  29. Synthesis and evaluation of Hsp90 inhibitors that contain the 1,4-naphthoquinone scaffold. Bioorg Med Chem. 2009 Jan 15; 17(2):634-40.
    View in: PubMed
    Score: 0.005
  30. Derrubone, an inhibitor of the Hsp90 protein folding machinery. J Nat Prod. 2007 Dec; 70(12):2014-8.
    View in: PubMed
    Score: 0.004
  31. Evidence for chaperone heterocomplexes containing both Hsp90 and VCP. Biochem Biophys Res Commun. 2005 Jun 17; 331(4):1331-7.
    View in: PubMed
    Score: 0.004
  32. Identification of crucial histidines for heme binding in the N-terminal domain of the heme-regulated eIF2alpha kinase. J Biol Chem. 2004 Feb 20; 279(8):6778-82.
    View in: PubMed
    Score: 0.003
  33. Identification of caspase 3-mediated cleavage and functional alteration of eukaryotic initiation factor 2alpha in apoptosis. J Biol Chem. 2000 Mar 31; 275(13):9314-23.
    View in: PubMed
    Score: 0.002
  34. Effects of geldanamycin, a heat-shock protein 90-binding agent, on T cell function and T cell nonreceptor protein tyrosine kinases. J Immunol. 2000 Mar 15; 164(6):2915-23.
    View in: PubMed
    Score: 0.002
  35. The outcome of poliovirus infections in K562 cells is cytolytic rather than persistent after hemin-induced differentiation. J Virol. 1996 Aug; 70(8):5525-32.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.