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Gorbsky, Gary

One or more keywords matched the following items that are connected to Gorbsky, Gary

Item Type	Name
Concept	HeLa Cells
Academic Article	The 3F3/2 anti-phosphoepitope antibody binds the mitotically phosphorylated anaphase-promoting complex/cyclosome.
Academic Article	Regulation of microtubule stability and mitotic progression by survivin.
Academic Article	Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1.
Academic Article	Live-cell fluorescence imaging for phenotypic analysis of mitosis.
Academic Article	CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation.
Academic Article	MPM-2 antibody-reactive phosphorylations can be created in detergent-extracted cells by kinetochore-bound and soluble kinases.
Academic Article	Both alpha and beta isoforms of mammalian DNA topoisomerase II associate with chromosomes in mitosis.
Academic Article	Survivin dynamics increases at centromeres during G2/M phase transition and is regulated by microtubule-attachment and Aurora B kinase activity.
Academic Article	The reversibility of mitotic exit in vertebrate cells.
Academic Article	Cohesion fatigue induces chromatid separation in cells delayed at metaphase.
Academic Article	Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events.
Academic Article	Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells.
Academic Article	Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105.
Academic Article	A high throughput, whole cell screen for small molecule inhibitors of the mitotic spindle checkpoint identifies OM137, a novel Aurora kinase inhibitor.
Academic Article	Ska3 is required for spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosis.
Academic Article	Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis.
Academic Article	Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited.
Academic Article	The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores.
Academic Article	Active MAP kinase in mitosis: localization at kinetochores and association with the motor protein CENP-E.
Academic Article	Tension-sensitive kinetochore phosphorylation in vitro.
Academic Article	Casein kinase II catalyzes a mitotic phosphorylation on threonine 1342 of human DNA topoisomerase IIalpha, which is recognized by the 3F3/2 phosphoepitope antibody.
Academic Article	The dephosphorylated form of the anaphase-promoting complex protein Cdc27/Apc3 concentrates on kinetochores and chromosome arms in mitosis.
Academic Article	PKD2 interacts and co-localizes with mDia1 to mitotic spindles of dividing cells: role of mDia1 IN PKD2 localization to mitotic spindles.
Academic Article	Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores.
Academic Article	Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons.
Academic Article	Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation.
Academic Article	The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit.
Academic Article	GTSE1 regulates spindle microtubule dynamics to control Aurora B kinase and Kif4A chromokinesin on chromosome arms.

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HeLa Cells