| Item Type | Name |
|
Concept
|
Histidine Kinase
|
|
Concept
|
Methyl-Accepting Chemotaxis Proteins
|
|
Concept
|
Protein Domains
|
|
Concept
|
Ammonium Sulfate
|
|
Concept
|
Antibodies, Monoclonal
|
|
Concept
|
Alcohol Oxidoreductases
|
|
Concept
|
Calcium
|
|
Concept
|
Acetyl Coenzyme A
|
|
Concept
|
Amino Acid Sequence
|
|
Concept
|
Acyl Coenzyme A
|
|
Concept
|
Carboxylic Ester Hydrolases
|
|
Concept
|
Bacillus subtilis
|
|
Concept
|
Base Sequence
|
|
Concept
|
Cations, Divalent
|
|
Concept
|
Cations, Monovalent
|
|
Concept
|
Cell Membrane
|
|
Concept
|
Cytosol
|
|
Concept
|
Computer Simulation
|
|
Concept
|
Deuterium
|
|
Concept
|
Cryptococcus neoformans
|
|
Concept
|
Cobalt
|
|
Concept
|
Cyclodextrins
|
|
Concept
|
Coenzyme A
|
|
Concept
|
Cysteine
|
|
Concept
|
Ferric Compounds
|
|
Concept
|
Ferrous Compounds
|
|
Concept
|
Drug Resistance, Microbial
|
|
Concept
|
Escherichia coli
|
|
Concept
|
Horses
|
|
Concept
|
Humans
|
|
Concept
|
Hydro-Lyases
|
|
Concept
|
Hydrogen Bonding
|
|
Concept
|
Genes, Regulator
|
|
Concept
|
Oxo-Acid-Lyases
|
|
Concept
|
Ketoglutaric Acids
|
|
Concept
|
Glutamine
|
|
Concept
|
Glutathione Transferase
|
|
Concept
|
Lysine
|
|
Concept
|
Magnesium
|
|
Concept
|
Manganese
|
|
Concept
|
Nitric Oxide
|
|
Concept
|
Nitrite Reductases
|
|
Concept
|
Nitrites
|
|
Concept
|
Nitroreductases
|
|
Concept
|
Nitroso Compounds
|
|
Concept
|
Myocardium
|
|
Concept
|
Myoglobin
|
|
Concept
|
NAD
|
|
Concept
|
NADP
|
|
Concept
|
Ions
|
|
Concept
|
Isocitrates
|
|
Concept
|
Plants
|
|
Concept
|
Methylation
|
|
Concept
|
Metronidazole
|
|
Concept
|
Phenotype
|
|
Concept
|
Phosphates
|
|
Concept
|
Potassium
|
|
Concept
|
Molecular Sequence Data
|
|
Concept
|
Phosphorylation
|
|
Concept
|
Phosphotransferases
|
|
Concept
|
Phylogeny
|
|
Concept
|
S-Adenosylmethionine
|
|
Concept
|
Saccharomyces cerevisiae
|
|
Concept
|
Saccharopine Dehydrogenases
|
|
Concept
|
Salmonella typhimurium
|
|
Concept
|
Seasons
|
|
Concept
|
Peptide Fragments
|
|
Concept
|
2-Aminoadipic Acid
|
|
Concept
|
2,6-Dichloroindophenol
|
|
Concept
|
Restriction Mapping
|
|
Concept
|
Structure-Activity Relationship
|
|
Concept
|
Sulfur
|
|
Concept
|
Vaccination
|
|
Concept
|
Point Mutation
|
|
Concept
|
Sequence Homology, Amino Acid
|
|
Concept
|
Sinorhizobium meliloti
|
|
Concept
|
Protein Structure, Secondary
|
|
Concept
|
Protein Structure, Tertiary
|
|
Concept
|
Oxidative Stress
|
|
Concept
|
Water
|
|
Concept
|
Water-Electrolyte Balance
|
|
Concept
|
Mutagenesis, Site-Directed
|
|
Concept
|
Glutamic Acid
|
|
Concept
|
Mutation, Missense
|
|
Concept
|
Catalytic Domain
|
|
Concept
|
Protein Renaturation
|
|
Concept
|
Regulon
|
|
Concept
|
Molecular Motor Proteins
|
|
Concept
|
Two-Hybrid System Techniques
|
|
Concept
|
Amino Acid Motifs
|
|
Concept
|
Crystallography, X-Ray
|
|
Concept
|
Escherichia coli Proteins
|
|
Concept
|
Amino Acid Substitution
|
|
Concept
|
Probability
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Drug Resistance, Fungal
|
|
Concept
|
Protein Kinases
|
|
Concept
|
Protein Processing, Post-Translational
|
|
Concept
|
Protons
|
|
Concept
|
2-Aminoadipate Transaminase
|
|
Concept
|
Sodium
|
|
Concept
|
Sodium Chloride
|
|
Concept
|
Spectrometry, Fluorescence
|
|
Concept
|
Tricarboxylic Acids
|
|
Concept
|
Gene Expression
|
|
Concept
|
Nucleotide Motifs
|
|
Concept
|
alpha-Cyclodextrins
|
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
|
Concept
|
Gene Regulatory Networks
|
|
Concept
|
Genes, Reporter
|
|
Concept
|
DNA Primers
|
|
Concept
|
Computational Biology
|
|
Concept
|
Antibodies, Neutralizing
|
|
Concept
|
Mitogen-Activated Protein Kinases
|
|
Concept
|
Genomics
|
|
Concept
|
Protein Interaction Domains and Motifs
|
|
Concept
|
Static Electricity
|
|
Concept
|
Molecular Dynamics Simulation
|
|
Concept
|
Apoenzymes
|
|
Concept
|
Arginine
|
|
Concept
|
Aspartic Acid
|
|
Concept
|
Cell Wall
|
|
Concept
|
Chemoreceptor Cells
|
|
Concept
|
DNA, Bacterial
|
|
Concept
|
Flagella
|
|
Concept
|
Flavin Mononucleotide
|
|
Concept
|
Organometallic Compounds
|
|
Concept
|
Osmosis
|
|
Concept
|
Osmotic Pressure
|
|
Concept
|
Oxaloacetates
|
|
Concept
|
Oxidation-Reduction
|
|
Academic Article
|
Immunodominance of antigenic site B over site A of hemagglutinin of recent H3N2 influenza viruses.
|
|
Academic Article
|
Purification, crystallization and preliminary X-ray diffraction analysis of the yeast phosphorelay protein YPD1.
|
|
Academic Article
|
Novel role for an HPt domain in stabilizing the phosphorylated state of a response regulator domain.
|
|
Academic Article
|
Interactions of organic nitroso compounds with metals.
|
|
Academic Article
|
Ssk1p response regulator binding surface on histidine-containing phosphotransfer protein Ypd1p.
|
|
Academic Article
|
The yeast YPD1/SLN1 complex: insights into molecular recognition in two-component signaling systems.
|
|
Academic Article
|
Kinetic analysis of YPD1-dependent phosphotransfer reactions in the yeast osmoregulatory phosphorelay system.
|
|
Academic Article
|
Acid-base chemical mechanism of homocitrate synthase from Saccharomyces cerevisiae.
|
|
Academic Article
|
Overall kinetic mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae.
|
|
Academic Article
|
Functional studies of the Ssk1p response regulator protein of Candida albicans as determined by phenotypic analysis of receiver domain point mutants.
|
|
Academic Article
|
Determinants of substrate specificity for saccharopine dehydrogenase from Saccharomyces cerevisiae.
|
|
Academic Article
|
Functional characterization of the phosphorelay protein Mpr1p from Schizosaccharomyces pombe.
|
|
Academic Article
|
Chemical mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
|
|
Academic Article
|
Potassium is an activator of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
|
|
Academic Article
|
Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts.
|
|
Academic Article
|
Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae.
|
|
Academic Article
|
Evidence for an induced conformational change in the catalytic mechanism of homoisocitrate dehydrogenase for Saccharomyces cerevisiae: Characterization of the D271N mutant enzyme.
|
|
Academic Article
|
Probing the chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae using site-directed mutagenesis.
|
|
Academic Article
|
Crystal structures of two nitroreductases from hypervirulent Clostridium difficile and functionally related interactions with the antibiotic metronidazole.
|
|
Academic Article
|
Role of the highly conserved G68 residue in the yeast phosphorelay protein Ypd1: implications for interactions between histidine phosphotransfer (HPt) and response regulator proteins.
|
|
Academic Article
|
Insights revealed by the co-crystal structure of the Saccharomyces cerevisiae histidine phosphotransfer protein Ypd1 and the receiver domain of its downstream response regulator Ssk1.
|
|
Academic Article
|
Conservation of structure and function among histidine-containing phosphotransfer (HPt) domains as revealed by the crystal structure of YPD1.
|
|
Academic Article
|
Histidine kinases and response regulator proteins in two-component signaling systems.
|
|
Academic Article
|
Co-crystallization of the yeast phosphorelay protein YPD1 with the SLN1 response-regulator domain and preliminary X-ray diffraction analysis.
|
|
Academic Article
|
Discrimination between different methylation states of chemotaxis receptor Tar by receptor methyltransferase CheR.
|
|
Academic Article
|
Kinetic mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae.
|
|
Academic Article
|
A common docking site for response regulators on the yeast phosphorelay protein YPD1.
|
|
Academic Article
|
A proposed proton shuttle mechanism for saccharopine dehydrogenase from Saccharomyces cerevisiae.
|
|
Academic Article
|
Complete kinetic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
|
|
Academic Article
|
Overall kinetic mechanism of saccharopine dehydrogenase (L-glutamate forming) from Saccharomyces cerevisiae.
|
|
Academic Article
|
Chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae.
|
|
Academic Article
|
Site-directed mutagenesis as a probe of the acid-base catalytic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
|
|
Academic Article
|
Fungal Skn7 stress responses and their relationship to virulence.
|
|
Academic Article
|
Crystal structure and DNA binding activity of a PadR family transcription regulator from hypervirulent Clostridium difficile R20291.
|
|
Academic Article
|
Use of restrained molecular dynamics to predict the conformations of phosphorylated receiver domains in two-component signaling systems.
|
|
Academic Article
|
Stabilization and characterization of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae.
|
|
Academic Article
|
Regulatory mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. I. Kinetic studies.
|
|
Academic Article
|
Crystal structures of the nitrite and nitric oxide complexes of horse heart myoglobin.
|
|
Academic Article
|
Crystal structures of manganese- and cobalt-substituted myoglobin in complex with NO and nitrite reveal unusual ligand conformations.
|
|
Academic Article
|
Crystal structures of ligand-bound saccharopine dehydrogenase from Saccharomyces cerevisiae.
|
|
Academic Article
|
Evidence for a catalytic dyad in the active site of homocitrate synthase from Saccharomyces cerevisiae.
|
|
Academic Article
|
Effects of osmolytes on the SLN1-YPD1-SSK1 phosphorelay system from Saccharomyces cerevisiae.
|
|
Academic Article
|
Kinetic and chemical mechanisms of homocitrate synthase from Thermus thermophilus.
|
|
Academic Article
|
Supporting role of lysine 13 and glutamate 16 in the acid-base mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae.
|
|
Academic Article
|
Histidine phosphotransfer proteins in fungal two-component signal transduction pathways.
|
|
Academic Article
|
Functional roles of conserved amino acid residues surrounding the phosphorylatable histidine of the yeast phosphorelay protein YPD1.
|
|
Academic Article
|
Bright lights, abundant operons--fluorescence and genomic technologies advance studies of bacterial locomotion and signal transduction: review of the BLAST meeting, Cuernavaca, Mexico, 14 to 19 January 2001.
|
|
Academic Article
|
Crystal structures of ferrous horse heart myoglobin complexed with nitric oxide and nitrosoethane.
|
|
Academic Article
|
Crystal structure of the his-tagged saccharopine reductase from Saccharomyces cerevisiae at 1.7-A resolution.
|
|
Academic Article
|
The alpha-aminoadipate pathway for lysine biosynthesis in fungi.
|
|
Academic Article
|
Crystal structure of a complex between the phosphorelay protein YPD1 and the response regulator domain of SLN1 bound to a phosphoryl analog.
|
|
Academic Article
|
Kinetic studies of the yeast His-Asp phosphorelay signaling pathway.
|
|
Academic Article
|
Genetic and biochemical analysis of the SLN1 pathway in Saccharomyces cerevisiae.
|
|
Academic Article
|
The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH.
|
|
Academic Article
|
Contribution of K99 and D319 to substrate binding and catalysis in the saccharopine dehydrogenase reaction.
|
|
Academic Article
|
Extended N-terminal region of the essential phosphorelay signaling protein Ypd1 from Cryptococcus neoformans contributes to structural stability, phosphostability and binding of calcium ions.
|
|
Academic Article
|
Regulatory Targets of the Response Regulator RR_1586 from Clostridioides difficile Identified Using a Bacterial One-Hybrid Screen.
|
|
Academic Article
|
Purification, crystallization, and preliminary X-ray diffraction analyses of the bacterial chemotaxis receptor modifying enzymes.
|
|
Academic Article
|
Crystal structure of the catalytic domain of the chemotaxis receptor methylesterase, CheB.
|
|
Grant
|
Oklahoma COBRE in Structural Biology
|
|
Academic Article
|
Response Regulator CD1688 Is a Negative Modulator of Sporulation in Clostridioides difficile.
|