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Gorbsky, Gary
One or more keywords matched the following items that are connected to
Gorbsky, Gary
Item Type
Name
Concept
Kinetochores
Academic Article
Mad2 binding by phosphorylated kinetochores links error detection and checkpoint action in mitosis.
Academic Article
The 3F3/2 anti-phosphoepitope antibody binds the mitotically phosphorylated anaphase-promoting complex/cyclosome.
Academic Article
Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1.
Academic Article
Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint.
Academic Article
Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant.
Academic Article
Phosphatase-regulated recruitment of the spindle- and kinetochore-associated (Ska) complex to kinetochores.
Academic Article
Multiple determinants and consequences of cohesion fatigue in mammalian cells.
Academic Article
Microtubules of the kinetochore fiber turn over in metaphase but not in anaphase.
Academic Article
Differential expression of a phosphoepitope at the kinetochores of moving chromosomes.
Academic Article
Microinjection of mitotic cells with the 3F3/2 anti-phosphoepitope antibody delays the onset of anaphase.
Academic Article
MPM-2 antibody-reactive phosphorylations can be created in detergent-extracted cells by kinetochore-bound and soluble kinases.
Academic Article
Rapid exchange of mammalian topoisomerase II alpha at kinetochores and chromosome arms in mitosis.
Academic Article
Kinetochores, microtubules and the metaphase checkpoint.
Academic Article
The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment.
Academic Article
The spindle checkpoint and chromosome segregation in meiosis.
Academic Article
Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events.
Academic Article
Protein dynamics at the kinetochore: cell cycle regulation of the metaphase to anaphase transition.
Academic Article
Elevating the level of Cdc34/Ubc3 ubiquitin-conjugating enzyme in mitosis inhibits association of CENP-E with kinetochores and blocks the metaphase alignment of chromosomes.
Academic Article
Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells.
Academic Article
Lysed cell models and isolated chromosomes for the study of kinetochore/centromere biochemistry in vitro.
Academic Article
Ska3 is required for spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosis.
Academic Article
Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis.
Academic Article
The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores.
Academic Article
Active MAP kinase in mitosis: localization at kinetochores and association with the motor protein CENP-E.
Academic Article
Tension-sensitive kinetochore phosphorylation in vitro.
Academic Article
Kinetochore "memory" of spindle checkpoint signaling in lysed mitotic cells.
Academic Article
The dephosphorylated form of the anaphase-promoting complex protein Cdc27/Apc3 concentrates on kinetochores and chromosome arms in mitosis.
Academic Article
The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity.
Academic Article
Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores.
Academic Article
Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin.
Academic Article
The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit.
Academic Article
Chromosomes move poleward in anaphase along stationary microtubules that coordinately disassemble from their kinetochore ends.
Academic Article
Cell-cycle-regulated localization of tyrosine and threonine phosphoepitopes at the kinetochores of mitotic chromosomes.
Academic Article
Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint.
Grant
Chromosome Movement in Prometaphase
Grant
Understanding Cell Division
Grant
A Cell Dynamics Microscope for Live Cell Fluorescence
Academic Article
Mps1 promotes poleward chromosome movements in meiotic prometaphase.
Academic Article
More than two populations of microtubules comprise the dynamic mitotic spindle.
Search Criteria
Kinetochores