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One or more keywords matched the following items that are connected to Gorbsky, Gary
Item TypeName
Concept Kinetochores
Academic Article Mad2 binding by phosphorylated kinetochores links error detection and checkpoint action in mitosis.
Academic Article The 3F3/2 anti-phosphoepitope antibody binds the mitotically phosphorylated anaphase-promoting complex/cyclosome.
Academic Article Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1.
Academic Article Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint.
Academic Article Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant.
Academic Article Phosphatase-regulated recruitment of the spindle- and kinetochore-associated (Ska) complex to kinetochores.
Academic Article Multiple determinants and consequences of cohesion fatigue in mammalian cells.
Academic Article Microtubules of the kinetochore fiber turn over in metaphase but not in anaphase.
Academic Article Differential expression of a phosphoepitope at the kinetochores of moving chromosomes.
Academic Article Microinjection of mitotic cells with the 3F3/2 anti-phosphoepitope antibody delays the onset of anaphase.
Academic Article MPM-2 antibody-reactive phosphorylations can be created in detergent-extracted cells by kinetochore-bound and soluble kinases.
Academic Article Rapid exchange of mammalian topoisomerase II alpha at kinetochores and chromosome arms in mitosis.
Academic Article Kinetochores, microtubules and the metaphase checkpoint.
Academic Article The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment.
Academic Article The spindle checkpoint and chromosome segregation in meiosis.
Academic Article Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events.
Academic Article Protein dynamics at the kinetochore: cell cycle regulation of the metaphase to anaphase transition.
Academic Article Elevating the level of Cdc34/Ubc3 ubiquitin-conjugating enzyme in mitosis inhibits association of CENP-E with kinetochores and blocks the metaphase alignment of chromosomes.
Academic Article Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells.
Academic Article Lysed cell models and isolated chromosomes for the study of kinetochore/centromere biochemistry in vitro.
Academic Article Ska3 is required for spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosis.
Academic Article Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis.
Academic Article The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores.
Academic Article Active MAP kinase in mitosis: localization at kinetochores and association with the motor protein CENP-E.
Academic Article Tension-sensitive kinetochore phosphorylation in vitro.
Academic Article Kinetochore "memory" of spindle checkpoint signaling in lysed mitotic cells.
Academic Article The dephosphorylated form of the anaphase-promoting complex protein Cdc27/Apc3 concentrates on kinetochores and chromosome arms in mitosis.
Academic Article The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity.
Academic Article Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores.
Academic Article Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin.
Academic Article The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit.
Academic Article Chromosomes move poleward in anaphase along stationary microtubules that coordinately disassemble from their kinetochore ends.
Academic Article Cell-cycle-regulated localization of tyrosine and threonine phosphoepitopes at the kinetochores of mitotic chromosomes.
Academic Article Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint.
Grant Chromosome Movement in Prometaphase
Grant Understanding Cell Division
Grant A Cell Dynamics Microscope for Live Cell Fluorescence
Academic Article Mps1 promotes poleward chromosome movements in meiotic prometaphase.
Academic Article More than two populations of microtubules comprise the dynamic mitotic spindle.
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  • Kinetochores