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Erlotinib is not effective in patients with JAK2V617F-positive polycythemia vera.
Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth.
Identification of an acquired JAK2 mutation in polycythemia vera.
The Jak2 inhibitor, G6, alleviates Jak2-V617F-mediated myeloproliferative neoplasia by providing significant therapeutic efficacy to the bone marrow.