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Zhao, Zhizhuang

One or more keywords matched the following items that are connected to Zhao, Zhizhuang

Item Type	Name
Concept	Janus Kinase Inhibitors
Concept	Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
Concept	Mitogen-Activated Protein Kinase 1
Concept	Protein Kinases
Concept	Protein-Tyrosine Kinases
Concept	Protein Kinase Inhibitors
Concept	p38 Mitogen-Activated Protein Kinases
Concept	Mitogen-Activated Protein Kinase 3
Concept	Receptor-Interacting Protein Serine-Threonine Kinases
Concept	Janus Kinases
Concept	Janus Kinase 2
Concept	Mitogen-Activated Protein Kinases
Concept	MAP Kinase Signaling System
Concept	fms-Like Tyrosine Kinase 3
Academic Article	MAPK-activated protein kinase-2 (MK2)-mediated formation and phosphorylation-regulated dissociation of the signal complex consisting of p38, MK2, Akt, and Hsp27.
Academic Article	Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice.
Academic Article	Aconitase regulation of erythropoiesis correlates with a novel licensing function in erythropoietin-induced ERK signaling.
Academic Article	The small molecule inhibitor G6 significantly reduces bone marrow fibrosis and the mutant burden in a mouse model of Jak2-mediated myelofibrosis.
Academic Article	Generation and characterization of a highly effective protein substrate for analysis of FLT3 activity.
Academic Article	SU11652 Inhibits tyrosine kinase activity of FLT3 and growth of MV-4-11 cells.
Academic Article	Elevated levels of mast cells are involved in pruritus associated with polycythemia vera in JAK2V617F transgenic mice.
Academic Article	Specific dephosphorylation of Janus Kinase 2 by protein tyrosine phosphatases.
Academic Article	Erlotinib is not effective in patients with JAK2V617F-positive polycythemia vera.
Academic Article	The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A.
Academic Article	Thrombopoietin is required for full phenotype expression in a JAK2V617F transgenic mouse model of polycythemia vera.
Academic Article	SPAP2, an Ig family receptor containing both ITIMs and ITAMs.
Academic Article	Role of tyrosine kinases and phosphatases in polycythemia vera.
Academic Article	Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth.
Academic Article	Characterization of a highly effective protein substrate for analysis of JAK2(V617F) Activity.
Academic Article	Development of a highly sensitive method for detection of JAK2V617F.
Academic Article	A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth.
Academic Article	Cardiac hypertrophy associated with myeloproliferative neoplasms in JAK2V617F transgenic mice.
Academic Article	Generation and characterization of a JAK2V617F-containing erythroleukemia cell line.
Academic Article	Tyrosine kinase inhibitors targeting FLT3 in the treatment of acute myeloid leukemia.
Academic Article	Blocking the function of tyrosine phosphatase SHP-2 by targeting its Src homology 2 domains.
Academic Article	Identification of an acquired JAK2 mutation in polycythemia vera.
Academic Article	Antagonism or synergism. Role of tyrosine phosphatases SHP-1 and SHP-2 in growth factor signaling.
Academic Article	Relevance of JAK2V617F positivity to hematological diseases--survey of samples from a clinical genetics laboratory.
Academic Article	The Jak2 inhibitor, G6, alleviates Jak2-V617F-mediated myeloproliferative neoplasia by providing significant therapeutic efficacy to the bone marrow.
Academic Article	Stem and progenitor cell subsets are affected by JAK2 signaling and can be monitored by flow cytometry.
Academic Article	JAK2(V617F): Prevalence in a large Chinese hospital population.
Academic Article	Detection of the JAK2V617F mutation by asymmetric PCR and melt curve analysis.
Academic Article	Tea contains potent inhibitors of tyrosine phosphatase PTP1B.
Academic Article	Identification of novel SAR properties of the Jak2 small molecule inhibitor G6: significance of the para-hydroxyl orientation.
Academic Article	Transposon mutagenesis reveals cooperation of ETS family transcription factors with signaling pathways in erythro-megakaryocytic leukemia.
Academic Article	Efficacy of ALK5 inhibition in myelofibrosis.
Academic Article	ASXL1 alteration cooperates with JAK2V617F to accelerate myelofibrosis.
Academic Article	miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2.
Grant	TYROSINE PHOSPHATASES IN SIGNAL TRANSDUCTION
Grant	Tyrosine Phosphatase PTP-MEG2 and Hematopoiesis
Grant	Tyrosine Kinase JAK2 and Myeloproliferative Disorders
Academic Article	Expression of a recombinant FLT3 ligand and its emtansine conjugate as a therapeutic candidate against acute myeloid leukemia cells with FLT3 expression.
Academic Article	Tyrosine Kinase ROR1 as a Target for Anti-Cancer Therapies.
Academic Article	HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression.
Academic Article	Bioinformatics analyses of combined databases identify shared differentially expressed genes in cancer and autoimmune disease.
Academic Article	Efficacy of SCF drug conjugate targeting c-KIT in gastrointestinal stromal tumor.
Academic Article	SHP-1 dephosphorylates 3BP2 and potentially downregulates 3BP2-mediated T cell antigen receptor signaling.
Academic Article	Enhanced RIPK3 kinase activity-dependent lytic cell death in M1 but not M2 macrophages.

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Phosphotransferases