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Tweten, Rodney

One or more keywords matched the following items that are connected to Tweten, Rodney

Item Type	Name
Concept	Cholesterol
Academic Article	Arresting pore formation of a cholesterol-dependent cytolysin by disulfide trapping synchronizes the insertion of the transmembrane beta-sheet from a prepore intermediate.
Academic Article	Mechanism of membrane insertion of a multimeric beta-barrel protein: perfringolysin O creates a pore using ordered and coupled conformational changes.
Academic Article	Membrane-dependent conformational changes initiate cholesterol-dependent cytolysin oligomerization and intersubunit beta-strand alignment.
Academic Article	Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin.
Academic Article	Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity.
Academic Article	The cholesterol-dependent cytolysin signature motif: a critical element in the allosteric pathway that couples membrane binding to pore assembly.
Academic Article	Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin.
Academic Article	Disulfide-bond scanning reveals assembly state and ß-strand tilt angle of the PFO ß-barrel.
Academic Article	The mechanism of membrane insertion for a cholesterol-dependent cytolysin: a novel paradigm for pore-forming toxins.
Academic Article	The cholesterol-dependent cytolysins.
Academic Article	Assembly and topography of the prepore complex in cholesterol-dependent cytolysins.
Academic Article	Prepore to pore transition of a cholesterol-dependent cytolysin visualized by electron microscopy.
Academic Article	Cholesterol-dependent cytolysins, a family of versatile pore-forming toxins.
Academic Article	Plasma membrane cholesterol content affects nitric oxide diffusion dynamics and signaling.
Academic Article	The Cholesterol-dependent Cytolysin Membrane-binding Interface Discriminates Lipid Environments of Cholesterol to Support ß-Barrel Pore Insertion.
Academic Article	A Key Motif in the Cholesterol-Dependent Cytolysins Reveals a Large Family of Related Proteins.
Academic Article	Structural insights into the membrane-anchoring mechanism of a cholesterol-dependent cytolysin.
Academic Article	The domains of a cholesterol-dependent cytolysin undergo a major FRET-detected rearrangement during pore formation.
Academic Article	Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins.
Academic Article	Characterization of a streptococcal cholesterol-dependent cytolysin with a lewis y and b specific lectin domain.
Academic Article	Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface.
Academic Article	Structural studies of Streptococcus pyogenes streptolysin O provide insights into the early steps of membrane penetration.
Academic Article	The Unique Molecular Choreography of Giant Pore Formation by the Cholesterol-Dependent Cytolysins of Gram-Positive Bacteria.
Academic Article	The molecular mechanism of pneumolysin, a virulence factor from Streptococcus pneumoniae.
Academic Article	The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane beta-hairpins.
Academic Article	Monomer-monomer interactions drive the prepore to pore conversion of a beta-barrel-forming cholesterol-dependent cytolysin.
Academic Article	Redefining cholesterol's role in the mechanism of the cholesterol-dependent cytolysins.
Academic Article	Human CD59 is a receptor for the cholesterol-dependent cytolysin intermedilysin.
Academic Article	Specific protein-membrane contacts are required for prepore and pore assembly by a cholesterol-dependent cytolysin.
Academic Article	Structural elements of the cholesterol-dependent cytolysins that are responsible for their cholesterol-sensitive membrane interactions.
Academic Article	Cholesterol exposure at the membrane surface is necessary and sufficient to trigger perfringolysin O binding.
Academic Article	Membrane assembly of the cholesterol-dependent cytolysin pore complex.
Academic Article	Monomer-monomer interactions propagate structural transitions necessary for pore formation by the cholesterol-dependent cytolysins.
Academic Article	Packing a punch: the mechanism of pore formation by cholesterol dependent cytolysins and membrane attack complex/perforin-like proteins.
Academic Article	Identification and characterization of the first cholesterol-dependent cytolysins from Gram-negative bacteria.
Academic Article	Mouse, but not human, ApoB-100 lipoprotein cholesterol is a potent innate inhibitor of Streptococcus pneumoniae pneumolysin.
Academic Article	An intermolecular electrostatic interaction controls the prepore-to-pore transition in a cholesterol-dependent cytolysin.
Academic Article	Stonefish toxin defines an ancient branch of the perforin-like superfamily.
Academic Article	Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins.
Academic Article	Cholesterol-dependent cytolysins: from water-soluble state to membrane pore.
Academic Article	Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form.
Grant	Pore Formation by Cholesterol Dependent Cytolysins
Grant	A Novel Cholesterol-Dependent Cytolysin Receptor
Grant	Pore Formation by Cholesterol Dependent Cytolysins
Academic Article	How protein engineering has revealed the molecular mechanisms of pore-forming toxins.
Academic Article	Cholesterol-dependent cytolysins: The outstanding questions.

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Cholesterol