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ELOVL4 protein preferentially elongates 20:5n3 to very long chain PUFAs over 20:4n6 and 22:6n3.
Endoplasmic reticulum microenvironment and conserved histidines govern ELOVL4 fatty acid elongase activity.
Biosynthesis of very long-chain polyunsaturated fatty acids in hepatocytes expressing ELOVL4.
Deciphering mutant ELOVL4 activity in autosomal-dominant Stargardt macular dystrophy.
Dominant Stargardt Macular Dystrophy (STGD3) and ELOVL4.