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Lessard, Christopher

One or more keywords matched the following properties of Lessard, Christopher

Property	Value
phone	405/271-2539

One or more keywords matched the following items that are connected to Lessard, Christopher

Item Type	Name
Concept	ADAM17 Protein
Concept	Tumor Necrosis Factor alpha-Induced Protein 3
Concept	Animals
Concept	Apolipoprotein L1
Concept	Age Factors
Concept	c-Mer Tyrosine Kinase
Concept	Histocompatibility Antigens Class II
Concept	Antibodies, Antinuclear
Concept	Alleles
Concept	African Americans
Concept	B-Lymphocytes
Concept	Base Sequence
Concept	Bayes Theorem
Concept	Cell Line
Concept	Cell Line, Transformed
Concept	Cell Movement
Concept	Biopsy
Concept	Chromosomes, Human, Pair 11
Concept	Chromosomes, Human, Pair 6
Concept	Chromosomes, Human, Pair 8
Concept	Cross-Sectional Studies
Concept	Ethylnitrosourea
Concept	Europe
Concept	Exons
Concept	Encephalomyelitis, Autoimmune, Experimental
Concept	Enzyme-Linked Immunosorbent Assay
Concept	Dose-Response Relationship, Radiation
Concept	Epithelium
Concept	Fibrosis
Concept	Histological Techniques
Concept	HLA Antigens
Concept	Hodgkin Disease
Concept	Humans
Concept	Immunodiffusion
Concept	Lip
Concept	Lipoproteins, HDL
Concept	Liver Cirrhosis, Biliary
Concept	Keratoconjunctivitis Sicca
Concept	Klinefelter Syndrome
Concept	Lupus Nephritis
Concept	Lymphocyte Activation
Concept	Lymphocytes
Concept	Lymphoma
Concept	Macrophages
Concept	Major Histocompatibility Complex
Concept	United Kingdom
Concept	Inflammation
Concept	Neuromyelitis Optica
Concept	Interferon Type I
Concept	Interferon-gamma
Concept	Interferons
Concept	Interleukins
Concept	Mycosis Fungoides
Concept	Mice, Inbred C57BL
Concept	Molecular Sequence Data
Concept	Mosaicism
Concept	Predictive Value of Tests
Concept	Saliva
Concept	Salivary Glands
Concept	Salivary Glands, Minor
Concept	Sarcoidosis
Concept	Rheumatoid Factor
Concept	Ribonucleoproteins
Concept	Severity of Illness Index
Concept	Sex Chromosome Aberrations
Concept	Risk
Concept	Risk Factors
Concept	ROC Curve
Concept	Pyruvate Dehydrogenase Complex
Concept	Transcription, Genetic
Concept	Histocompatibility Antigens Class I
Concept	Receptors, Antigen, T-Cell
Concept	Xeroderma Pigmentosum
Concept	CD4-Positive T-Lymphocytes
Concept	Receptors, Fc
Concept	2',5'-Oligoadenylate Synthetase
Concept	CD4 Antigens
Concept	Meta-Analysis as Topic
Concept	Reproducibility of Results
Concept	HLA-DR3 Antigen
Concept	Cohort Studies
Concept	Sulfur Radioisotopes
Concept	In Situ Hybridization, Fluorescence
Concept	Vimentin
Concept	Vitamin B 12
Concept	Lymphoma, B-Cell, Marginal Zone
Concept	Hyaluronan Receptors
Concept	Epitopes, T-Lymphocyte
Concept	Mutagenesis
Concept	NF-kappa B
Concept	Interleukin-12
Concept	Myosin Heavy Chains
Concept	Vascular Cell Adhesion Molecule-1
Concept	Lymphoma, B-Cell
Concept	Reverse Transcriptase Polymerase Chain Reaction
Concept	Mice, Inbred NOD
Concept	Polymorphism, Single Nucleotide
Concept	RNA, Small Cytoplasmic
Concept	Interleukin-17
Concept	Interleukin-18
Concept	Germ-Line Mutation
Concept	Molecular Motor Proteins
Concept	Databases, Genetic
Concept	beta Karyopherins
Concept	Mice, Knockout
Concept	Promoter Regions, Genetic
Concept	Genetic Predisposition to Disease
Concept	Prospective Studies
Concept	American Native Continental Ancestry Group
Concept	Ubiquitin-Conjugating Enzymes
Concept	Ubiquitin-Protein Ligases
Concept	Somatic Hypermutation, Immunoglobulin
Concept	Sjogren's Syndrome
Concept	Skin Neoplasms
Concept	Mice
Concept	Genome-Wide Association Study
Concept	Trisomy
Concept	Turner Syndrome
Concept	Ultraviolet Rays
Concept	United States
Concept	Interleukin-6
Concept	Prevalence
Concept	Multivariate Analysis
Concept	Linear Models
Concept	Logistic Models
Concept	Odds Ratio
Concept	Case-Control Studies
Concept	Transcriptome
Concept	Immunophenotyping
Concept	HLA-DRB1 Chains
Concept	HLA-DQ beta-Chains
Concept	Thymocytes
Concept	Sex Distribution
Concept	Adaptor Proteins, Signal Transducing
Concept	Cell Proliferation
Concept	OX40 Ligand
Concept	Quantitative Trait Loci
Concept	Proteomics
Concept	Chromosomes, Human, X
Concept	Chromosomes, Human, Y
Concept	Antigen Presentation
Concept	NADPH Oxidases
Concept	Computational Biology
Concept	DNA Breaks, Double-Stranded
Concept	Republic of Korea
Concept	Area Under Curve
Concept	Mannose-Binding Protein-Associated Serine Proteases
Concept	STAT4 Transcription Factor
Concept	Interferon Regulatory Factors
Concept	Receptors, CXCR5
Concept	Genomics
Concept	Electrophoretic Mobility Shift Assay
Concept	Receptors, Purinergic P2Y2
Concept	Receptors, Purinergic P2X7
Concept	Th17 Cells
Concept	Sex Chromosome Disorders of Sex Development
Concept	Microarray Analysis
Concept	Microscopy, Electron, Transmission
Concept	Ikaros Transcription Factor
Concept	Natural Cytotoxicity Triggering Receptor 3
Concept	Genetic Loci
Concept	Apolipoproteins
Concept	Arthritis, Rheumatoid
Concept	Asian Americans
Concept	Autoantibodies
Concept	Autoantigens
Concept	Cells, Cultured
Concept	Diagnostic Errors
Concept	Disease Models, Animal
Concept	Disease Susceptibility
Concept	DNA Repair
Concept	Florida
Concept	Flow Cytometry
Concept	Follow-Up Studies
Concept	France
Concept	Hypergammaglobulinemia
Concept	Immunohistochemistry
Concept	Indians, North American
Concept	Infertility, Male
Concept	Methionine
Concept	Oklahoma
Academic Article	Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica.
Academic Article	Brief Report: Patients With Primary Sjögren's Syndrome Who Are Positive for Autoantibodies to Tripartite Motif-Containing Protein 38 Show Greater Disease Severity.
Academic Article	Cytokine profiles show heterogeneity of interferon-ß response in multiple sclerosis patients.
Academic Article	Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations.
Academic Article	Peripheral blood gene expression profiling in Sjögren's syndrome.
Academic Article	Genetics of Sjögren's syndrome in the genome-wide association era.
Academic Article	Interferons in Sjögren's Syndrome: Genes, Mechanisms, and Effects.
Academic Article	Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.
Academic Article	Germline variation of TNFAIP3 in primary Sjögren's syndrome-associated lymphoma.
Academic Article	X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.
Academic Article	Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome.
Academic Article	A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases.
Academic Article	Effect of Tobacco Smoking on The Clinical, Histopathological, and Serological Manifestations of Sjögren's Syndrome.
Academic Article	Fatty infiltration of the minor salivary glands is a selective feature of aging but not Sjögren's syndrome.
Academic Article	American Indians Have a Higher Risk of Sjögren's Syndrome and More Disease Activity Than European Americans and African Americans.
Academic Article	Genes and Sjögren's syndrome.
Academic Article	Recent insights into the genetic basis of systemic lupus erythematosus.
Academic Article	Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study.
Academic Article	The genomics of autoimmune disease in the era of genome-wide association studies and beyond.
Academic Article	Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus.
Academic Article	Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.
Academic Article	Relation of sensory peripheral neuropathy in Sjögren syndrome to anti-Ro/SSA.
Academic Article	Germline and somatic genetic variations of TNFAIP3 in lymphoma complicating primary Sjogren's syndrome.
Academic Article	Detrimental effects of duplicate reads and low complexity regions on RNA- and ChIP-seq data.
Academic Article	Polygenic risk assessment reveals pleiotropy between sarcoidosis and inflammatory disorders in the context of genetic ancestry.
Academic Article	Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.
Academic Article	Evidence of Alternative Modes of B Cell Activation Involving Acquired Fab Regions of N-Glycosylation in Antibody-Secreting Cells Infiltrating the Labial Salivary Glands of Patients With Sjögren's Syndrome.
Academic Article	Transcriptomic and Network Analysis of Minor Salivary Glands of Patients With Primary Sjögren's Syndrome.
Academic Article	Alkaline unwinding flow cytometry assay to measure nucleotide excision repair.
Academic Article	Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.
Academic Article	Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.
Academic Article	A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus.
Academic Article	Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren's syndrome.
Academic Article	Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription.
Academic Article	Single-cell analysis of glandular T cell receptors in Sjögren's syndrome.
Academic Article	Genetics in Sjögren Syndrome.
Academic Article	Rare X Chromosome Abnormalities in Systemic Lupus Erythematosus and Sjögren's Syndrome.
Academic Article	Minor salivary gland fibrosis in Sjögren's syndrome is elevated, associated with focus score and not solely a consequence of aging.
Academic Article	Corrigendum to "Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome" [Clin. Immunol. 168 (2016) 25-29].
Academic Article	Gene expression profiling of epithelium-associated FcRL4+ B cells in primary Sjögren's syndrome reveals a pathogenic signature.
Academic Article	Sjögren's Syndrome Minor Salivary Gland CD4+ Memory T Cells Associate with Glandular Disease Features and have a Germinal Center T Follicular Helper Transcriptional Profile.
Academic Article	Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.
Academic Article	Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus.
Academic Article	Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis.
Academic Article	NCR3/NKp30 contributes to pathogenesis in primary Sjogren's syndrome.
Academic Article	Comparison of the American-European Consensus Group Sjogren's syndrome classification criteria to newly proposed American College of Rheumatology criteria in a large, carefully characterised sicca cohort.
Academic Article	Antibody-secreting cell specificity in labial salivary glands reflects the clinical presentation and serology in patients with Sjögren's syndrome.
Academic Article	The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
Academic Article	Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.
Academic Article	Previous diagnosis of Sjögren's Syndrome as rheumatoid arthritis or systemic lupus erythematosus.
Academic Article	Sjögren Syndrome without Focal Lymphocytic Infiltration of the Salivary Glands.
Academic Article	Reproducibility of Ocular Surface Staining in the Assessment of Sjögren Syndrome-Related Keratoconjunctivitis Sicca: Implications on Disease Classification.
Grant	Functional Evaluation of Established Sjogren's Syndrome Immune Response Loci
Grant	Discovery and Characterization of Genetic Risk Loci in Sjogren's Syndrome
Academic Article	Mutagenesis-generated mouse models of human infertility with abnormal sperm.
Academic Article	Defective Efferocytosis in a Murine Model of Sjögren's Syndrome Is Mediated by Dysfunctional Mer Tyrosine Kinase Receptor.
Academic Article	Genetic variants at the RTP4/MASP1 locus are associated with fatigue in Scandinavian patients with primary Sjögren's syndrome.
Academic Article	Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells.
Academic Article	Variability of Primary Sjögren's Syndrome Is Driven by Interferon a and Interferon a Blood Levels Are Associated With the Class II HLA-DQ Locus.
Academic Article	Dysregulated long non-coding RNA in Sjögren's disease impacts both interferon and adaptive immune responses.
Academic Article	Author Correction: Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells.
Academic Article	Ancestral origins are associated with SARS-CoV-2 susceptibility and protection in a Florida patient population.
Academic Article	Author Correction: Genome-wide association study identifies Sj?gren's risk loci with functional implications in immune and glandular cells.
Academic Article	Identification of new candidate drugs for primary Sj?gren's syndrome using a drug repurposing transcriptomic approach.
Academic Article	Anti-vimentin antibodies are associated with higher severity of Sj?gren's disease.
Academic Article	Autoantibodies identify primary Sj?gren's syndrome in patients lacking serum IgG specific for Ro/SS-A and La/SS-B.
Academic Article	TScan-II: A genome-scale platform for the de novo identification of CD4+ T?cell epitopes.
Academic Article	GZMK+CD8+ T cells Target a Specific Acinar Cell Type in Sj?gren's Disease.

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