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SWI/SNF chromatin-remodeling enzymes Brahma-related gene 1 (BRG1) and Brahma (BRM) are dispensable in multiple models of postnatal angiogenesis but are required for vascular integrity in infant mice.
An inhibitor of endothelial ETS transcription factors promotes physiologic and therapeutic vessel regression.
Genetic analysis of sorting nexins 1 and 2 reveals a redundant and essential function in mice.