| Item Type | Name |
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Concept
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ELAV-Like Protein 1
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Concept
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Protein Biosynthesis
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Concept
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Receptors, G-Protein-Coupled
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Concept
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Protein Isoforms
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Concept
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Protein Binding
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Concept
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Protein Kinases
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Concept
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Adenomatous Polyposis Coli Protein
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Concept
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Protein Interaction Mapping
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Concept
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bcl-X Protein
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Concept
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BH3 Interacting Domain Death Agonist Protein
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Concept
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bcl-2-Associated X Protein
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Concept
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Oncogene Protein v-akt
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Concept
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Tumor Suppressor Protein p53
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Concept
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CDC2 Protein Kinase
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Concept
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Protein Kinase Inhibitors
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Concept
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JNK Mitogen-Activated Protein Kinases
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Concept
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p38 Mitogen-Activated Protein Kinases
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Concept
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Amyloid Precursor Protein Secretases
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Concept
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Mitogen-Activated Protein Kinases
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Concept
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Zonula Occludens-1 Protein
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Concept
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Protein Transport
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Concept
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Protein Sorting Signals
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Concept
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Ataxia Telangiectasia Mutated Proteins
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|
Concept
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Myeloid Cell Leukemia Sequence 1 Protein
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|
Concept
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TNF Receptor-Associated Death Domain Protein
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|
Concept
|
Twist-Related Protein 1
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Concept
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Lysosomal-Associated Membrane Protein 1
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Academic Article
|
DCLK1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition.
|
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Academic Article
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Hepatitis C virus-induced cancer stem cell-like signatures in cell culture and murine tumor xenografts.
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Academic Article
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APSA Awardee Submission: Tumor/cancer stem cell marker doublecortin-like kinase 1 in liver diseases.
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Academic Article
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XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism.
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Academic Article
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Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1.
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Academic Article
|
Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells.
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Academic Article
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Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases.
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Academic Article
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Intestinal tuft cells regulate the ATM mediated DNA Damage response via Dclk1 dependent mechanism for crypt restitution following radiation injury.
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Academic Article
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Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells.
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Academic Article
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Dietary Pectin Increases Intestinal Crypt Stem Cell Survival following Radiation Injury.
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Academic Article
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Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis.
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Academic Article
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Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewal.
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Academic Article
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Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism.
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Academic Article
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DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer.
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Academic Article
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Brief report: Dclk1 deletion in tuft cells results in impaired epithelial repair after radiation injury.
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Academic Article
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Fluvastatin interferes with hepatitis C virus replication via microtubule bundling and a doublecortin-like kinase-mediated mechanism.
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Academic Article
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Inhibition of Notch signaling reduces the number of surviving Dclk1+ reserve crypt epithelial stem cells following radiation injury.
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Academic Article
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Doublecortin-like kinase 1 promotes hepatocyte clonogenicity and oncogenic programming via non-canonical ß-catenin-dependent mechanism.
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Academic Article
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Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2.
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Academic Article
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Dysregulation of Reg gene expression occurs early in gastrointestinal tumorigenesis and regulates anti-apoptotic genes.
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Academic Article
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Novel intestinal splice variants of RNA-binding protein CUGBP2: isoform-specific effects on mitotic catastrophe.
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Academic Article
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Translation inhibition during cell cycle arrest and apoptosis: Mcl-1 is a novel target for RNA binding protein CUGBP2.
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Academic Article
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CUGBP2 downregulation by prostaglandin E2 protects colon cancer cells from radiation-induced mitotic catastrophe.
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Academic Article
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Activation of apoptosis by 1-hydroxy-5,7-dimethoxy-2-naphthalene-carboxaldehyde, a novel compound from Aegle marmelos.
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Academic Article
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HuR and TTP: two RNA binding proteins that deliver message from the 3' end.
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Academic Article
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Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis.
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Academic Article
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Identification of a novel putative pancreatic stem/progenitor cell marker DCAMKL-1 in normal mouse pancreas.
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Academic Article
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Identification of the putative intestinal stem cell marker doublecortin and CaM kinase-like-1 in Barrett's esophagus and esophageal adenocarcinoma.
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Academic Article
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Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism.
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Academic Article
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Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
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Academic Article
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DCLK1 is detectable in plasma of patients with Barrett's esophagus and esophageal adenocarcinoma.
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Academic Article
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Dynamic antagonism between RNA-binding protein CUGBP2 and cyclooxygenase-2-mediated prostaglandin E2 in radiation damage.
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Academic Article
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PEGylated murine Granulocyte-macrophage colony-stimulating factor: production, purification, and characterization.
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Academic Article
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Gastrin-mediated interleukin-8 and cyclooxygenase-2 gene expression: differential transcriptional and posttranscriptional mechanisms.
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Academic Article
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Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastrophe.
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Academic Article
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Knockdown of RNA binding protein musashi-1 leads to tumor regression in vivo.
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Academic Article
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Selective blockade of DCAMKL-1 results in tumor growth arrest by a Let-7a MicroRNA-dependent mechanism.
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Academic Article
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14-3-3sigma-dependent resistance to cisplatin.
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Academic Article
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Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression.
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Academic Article
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Survival of Patients with Gastrointestinal Cancers Can Be Predicted by a Surrogate microRNA Signature for Cancer Stem-like Cells Marked by DCLK1 Kinase.
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Academic Article
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ZIP4 Promotes Muscle Wasting and Cachexia in Mice With Orthotopic Pancreatic Tumors by Stimulating RAB27B-Regulated Release of Extracellular Vesicles From Cancer Cells.
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Academic Article
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ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin a3ß1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells.
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Academic Article
|
Apobec-1 protects intestine from radiation injury through posttranscriptional regulation of cyclooxygenase-2 expression.
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|
Academic Article
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Functional antagonism between RNA binding proteins HuR and CUGBP2 determines the fate of COX-2 mRNA translation.
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Academic Article
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Doublecortin and CaM kinase-like-1 and leucine-rich-repeat-containing G-protein-coupled receptor mark quiescent and cycling intestinal stem cells, respectively.
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Academic Article
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DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism.
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Academic Article
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DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma.
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Academic Article
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Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer.
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|
Academic Article
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ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism.
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Academic Article
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Dclk1 in tuft cells promotes inflammation-driven epithelial restitution and mitigates chronic colitis.
|
|
Academic Article
|
Identification of a novel putative gastrointestinal stem cell and adenoma stem cell marker, doublecortin and CaM kinase-like-1, following radiation injury and in adenomatous polyposis coli/multiple intestinal neoplasia mice.
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|
Academic Article
|
Cancer stem cells: a novel paradigm for cancer prevention and treatment.
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|
Academic Article
|
RNA binding protein CUGBP2/CELF2 mediates curcumin-induced mitotic catastrophe of pancreatic cancer cells.
|
|
Academic Article
|
Dclk1 Defines Quiescent Pancreatic Progenitors that Promote Injury-Induced Regeneration and Tumorigenesis.
|
|
Academic Article
|
DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization.
|
|
Grant
|
Targeting DCLK1 kinase activity in pancreatic cancer
|
|
Grant
|
PROSTAGLANDIN E2 RECEPTORS IN GASTROINTESTINAL INJURY
|
|
Grant
|
Isolation and Characterization of Intestinal Stem Cells Using Novel Markers (RP)
|
|
Grant
|
PROSTAGLANDINS AND GASTROINTESTINAL DNA DAMAGE
|
|
Academic Article
|
Reg4 Interacts with CD44 to Regulate Proliferation and Stemness of Colorectal and Pancreatic Cancer Cells.
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|
Academic Article
|
Epigenetic Landscape and Therapeutic Implication of Gene Isoforms of Doublecortin-Like Kinase 1 for Cancer Stem Cells.
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