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Saline Solution, Hypertonic
Hypertonic saline alteration of the PMN cytoskeleton: implications for signal transduction and the cytotoxic response.
Hypertonic saline attenuation of the neutrophil cytotoxic response is reversed upon restoration of normotonicity and reestablished by repeated hypertonic challenge.
Hyperosmolarity abrogates neutrophil cytotoxicity provoked by post-shock mesenteric lymph.
Hypertonic saline attenuation of polymorphonuclear neutrophil cytotoxicity: timing is everything.
Hypertonic saline activation of p38 MAPK primes the PMN respiratory burst.
Clinically relevant hypertonicity prevents stored blood- and lipid-mediated delayed neutrophil apoptosis independent of p38 MAPK or caspase-3 activation.
Hypertonic saline inhibits neutrophil (PMN) priming via attenuation of p38 MAPK signaling.