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Design, synthesis, and biological activity of bicyclic radester analogues as Hsp90 inhibitors.
Design, synthesis, and biological evaluation of conformationally constrained cis-amide Hsp90 inhibitors.
Evolution of a 4-Benzyloxy-benzylamino Chemotype to Provide Efficacious, Potent, and Isoform Selective PPARa Agonists as Leads for Retinal Disorders.
Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding.
Development of a Grp94 inhibitor.
Total syntheses of (-)-pyrimidoblamic acid and P-3A.