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Xia, Lijun

One or more keywords matched the following items that are connected to Xia, Lijun

Item Type	Name
Concept	Mice, Inbred C57BL
Concept	Mice, Inbred Strains
Concept	Mice, Transgenic
Concept	Mice, SCID
Concept	Mice, Inbred NOD
Concept	Mice, Knockout
Concept	Mice
Concept	Mice, 129 Strain
Academic Article	Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells.
Academic Article	Loss of mucin-type O-glycans impairs the integrity of the glomerular filtration barrier in the mouse kidney.
Academic Article	Platelet TGF-ß1 deficiency decreases liver fibrosis in a mouse model of liver injury.
Academic Article	P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flow.
Academic Article	Bone marrow dysfunction in mice lacking the cytokine receptor gp130 in endothelial cells.
Academic Article	Targeted disruption of the gene encoding core 1 beta1-3-galactosyltransferase (T-synthase) causes embryonic lethality and defective angiogenesis in mice.
Academic Article	Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice.
Academic Article	Core 1-derived O-glycans are essential E-selectin ligands on neutrophils.
Academic Article	Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling.
Academic Article	Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2.
Academic Article	Molecular and cellular mechanisms of lymphatic vascular maturation.
Academic Article	Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.
Academic Article	Podoplanin requires sialylated O-glycans for stable expression on lymphatic endothelial cells and for interaction with platelets.
Academic Article	Core 1- and 3-derived O-glycans collectively maintain the colonic mucus barrier and protect against spontaneous colitis in mice.
Academic Article	L-selectin mechanochemistry restricts neutrophil priming in vivo.
Academic Article	Divergent inducible expression of P-selectin and E-selectin in mice and primates.
Academic Article	Defective angiogenesis and fatal embryonic hemorrhage in mice lacking core 1-derived O-glycans.
Academic Article	Surface fucosylation of human cord blood cells augments binding to P-selectin and E-selectin and enhances engraftment in bone marrow.
Academic Article	Differential regulation of human and murine P-selectin expression and function in vivo.
Academic Article	Cytoplasmic domain of P-selectin glycoprotein ligand-1 facilitates dimerization and export from the endoplasmic reticulum.
Academic Article	Trisomy 8: a common finding in mouse embryonic stem (ES) cell lines.
Academic Article	Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma.
Academic Article	Loss of intestinal O-glycans promotes spontaneous duodenal tumors.
Academic Article	Mechanotransduction activates canonical Wnt/ß-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves.
Academic Article	Comparison of promoters for the murine and human P-selectin genes suggests species-specific and conserved mechanisms for transcriptional regulation in endothelial cells.
Academic Article	Tumor necrosis factor-alpha- or lipopolysaccharide-induced expression of the murine P-selectin gene in endothelial cells involves novel kappaB sites and a variant activating transcription factor/cAMP response element.
Academic Article	P-selectin glycoprotein ligand-1 is highly expressed on Ly-6Chi monocytes and a major determinant for Ly-6Chi monocyte recruitment to sites of atherosclerosis in mice.
Academic Article	Separable requirements for cytoplasmic domain of PSGL-1 in leukocyte rolling and signaling under flow.
Academic Article	Core 3-derived O-glycans are essential for intestinal mucus barrier function.
Academic Article	Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency.
Academic Article	Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development.
Academic Article	O-glycans direct selectin ligands to lipid rafts on leukocytes.
Academic Article	Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice.
Academic Article	Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development.
Academic Article	Proximal colon-derived O-glycosylated mucus encapsulates and modulates the microbiota.
Academic Article	N-terminal residues in murine P-selectin glycoprotein ligand-1 required for binding to murine P-selectin.
Academic Article	Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans.
Academic Article	Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice.
Academic Article	Carcinoma mucins trigger reciprocal activation of platelets and neutrophils in a murine model of Trousseau syndrome.
Academic Article	Activation of AMP-activated protein kinase a2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo.
Academic Article	Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice.
Grant	Role of Mucin-type O-glycans in Intestinal Inflammation
Grant	Protein-glycan interactions in the vascular system
Grant	Platelet CLEC-2 regulation of vascular integrity during inflammation
Grant	Podoplanin-mediated platelet activation and vascular integrity in the developing brain
Grant	Site-1 protease-mediated lipid metabolism in lymphatic vascular development
Grant	Platelet CLEC-2 in Arterial Thrombosis
Academic Article	Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin.
Academic Article	Endothelial VWF is critical for the pathogenesis of vaso-occlusive episode in a mouse model of sickle cell disease.

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