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Metabolism of a sulfur-containing heteroarotionoid antitumor agent, SHetA2, using liquid chromatography/tandem mass spectrometry.
Activity of oxygen-versus sulfur-containing analogs of the Flex-Het anticancer agent SHetA2.
Synthesis of flexible sulfur-containing heteroarotinoids that induce apoptosis and reactive oxygen species with discrimination between malignant and benign cells.
Selective growth inhibition of cancer cells by L-methioninase-containing fusion protein targeted to the urokinase receptor.