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One or more keywords matched the following items that are connected to Gaffney, Patrick
Item TypeName
Concept Genome, Protozoan
Concept Genome-Wide Association Study
Concept Genome, Human
Academic Article Genome scan of human systemic lupus erythematosus by regression modeling: evidence of linkage and epistasis at 4p16-15.2.
Academic Article Genetic associations of LYN with systemic lupus erythematosus.
Academic Article Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations.
Academic Article Variation in the upstream region of P-Selectin (SELP) is a risk factor for SLE.
Academic Article Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
Academic Article Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
Academic Article GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.
Academic Article Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
Academic Article Identification of a New Susceptibility Locus for Systemic Lupus Erythematosus on Chromosome 12 in Individuals of European Ancestry.
Academic Article Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.
Academic Article From association to mechanism in complex disease genetics: the role of the 3D genome.
Academic Article Identification of new SLE-associated genes with a two-step Bayesian study design.
Academic Article Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.
Academic Article The genomics of autoimmune disease in the era of genome-wide association studies and beyond.
Academic Article Encore: Genetic Association Interaction Network centrality pipeline and application to SLE exome data.
Academic Article Forward genetic screening identifies a small molecule that blocks Toxoplasma gondii growth by inhibiting both host- and parasite-encoded kinases.
Academic Article Genome screening in human systemic lupus erythematosus: results from a second Minnesota cohort and combined analyses of 187 sib-pair families.
Academic Article Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.
Academic Article Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries.
Academic Article Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.
Academic Article Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.
Academic Article Disease mechanisms in rheumatology--tools and pathways: defining functional genetic variants in autoimmune diseases.
Academic Article Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.
Academic Article Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks.
Academic Article A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families.
Academic Article Meta-analysis of genome-wide linkage studies of systemic lupus erythematosus.
Academic Article Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
Academic Article Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.
Academic Article A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap.
Academic Article Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.
Academic Article Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31.
Academic Article Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus.
Grant Candidate Causal Variants in Systemic Lupus Erythematosus
Grant Epigenome-Guided Causal Variant Discovery and Mechanisms
Grant Comprehensive Candidate Pathway Analysis in SLE
Grant Functional Mechanisms of Causal Variants in Systemic Lupus Erythematosus
Grant Comprehensive Candidate Pathway Analysis in SLE
Academic Article CD4+?T cells from children with active juvenile idiopathic arthritis show altered chromatin features associated with transcriptional abnormalities.
Academic Article Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits.
Grant Disease and Race Specific Single-cell Epigenetic Mechanisms in Human SLE
Academic Article Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells.
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