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Gaffney, Patrick
One or more keywords matched the following items that are connected to
Gaffney, Patrick
Item Type
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Concept
Interferon Regulatory Factors
Academic Article
Exon 6 variants carried on systemic lupus erythematosus (SLE) risk haplotypes modulate IRF5 function.
Academic Article
IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus.
Academic Article
Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.
Academic Article
Effects of IRF5 lupus risk haplotype on pathways predicted to influence B cell functions.
Academic Article
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.
Academic Article
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
Academic Article
Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.
Academic Article
The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
Academic Article
Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.
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Interferon Regulatory Factors