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One or more keywords matched the following items that are connected to Gaffney, Patrick
Item TypeName
Concept Interferon-Induced Helicase, IFIH1
Concept Interferon Type I
Concept Interferons
Concept Interferon-alpha
Concept Interferon-beta
Concept Receptors, Interferon
Concept Interferon Regulatory Factors
Academic Article Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus.
Academic Article Peripheral blood gene expression profiling in Sjögren's syndrome.
Academic Article Association of IFIH1 and pro-inflammatory mediators: Potential new clues in SLE-associated pathogenesis.
Academic Article Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.
Academic Article Exon 6 variants carried on systemic lupus erythematosus (SLE) risk haplotypes modulate IRF5 function.
Academic Article The role of genetic variation near interferon-kappa in systemic lupus erythematosus.
Academic Article IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus.
Academic Article Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.
Academic Article Effects of IRF5 lupus risk haplotype on pathways predicted to influence B cell functions.
Academic Article Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.
Academic Article Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.
Academic Article Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
Academic Article Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.
Academic Article Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus.
Academic Article The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
Academic Article Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.
Academic Article Human effector B lymphocytes express ARID3a and secrete interferon alpha.
Grant Epigenome-Guided Causal Variant Discovery and Mechanisms
Grant TNFAIP3 (A20) and Susceptibility to Systemic Lupus Erythematosus
Grant Comprehensive Candidate Pathway Analysis in SLE
Academic Article Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits.
Grant Disease and Race Specific Single-cell Epigenetic Mechanisms in Human SLE
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  • Interferons