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One or more keywords matched the following items that are connected to
Gaffney, Patrick
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Concept
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Interferon-Induced Helicase, IFIH1
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Concept
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Interferon Type I
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Concept
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Interferons
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Concept
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Interferon-alpha
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Concept
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Interferon-beta
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Concept
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Receptors, Interferon
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Concept
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Interferon Regulatory Factors
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Academic Article
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Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus.
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Academic Article
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Peripheral blood gene expression profiling in Sjögren's syndrome.
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Academic Article
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Association of IFIH1 and pro-inflammatory mediators: Potential new clues in SLE-associated pathogenesis.
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Academic Article
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Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.
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Academic Article
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Exon 6 variants carried on systemic lupus erythematosus (SLE) risk haplotypes modulate IRF5 function.
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Academic Article
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The role of genetic variation near interferon-kappa in systemic lupus erythematosus.
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Academic Article
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IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus.
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Academic Article
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Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.
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Academic Article
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Effects of IRF5 lupus risk haplotype on pathways predicted to influence B cell functions.
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Academic Article
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Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.
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Academic Article
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Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.
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Academic Article
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Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
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Academic Article
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Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.
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Academic Article
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Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus.
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Academic Article
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The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
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Academic Article
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Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.
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Academic Article
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Human effector B lymphocytes express ARID3a and secrete interferon alpha.
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Grant
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Epigenome-Guided Causal Variant Discovery and Mechanisms
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Grant
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TNFAIP3 (A20) and Susceptibility to Systemic Lupus Erythematosus
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Grant
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Comprehensive Candidate Pathway Analysis in SLE
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Academic Article
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Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits.
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Grant
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Disease and Race Specific Single-cell Epigenetic Mechanisms in Human SLE
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